دورية أكاديمية
أعرض في EDS

Advances of Genomic Medicine in Psoriatic Arthritis.

التفاصيل البيبلوغرافية
العنوان: Advances of Genomic Medicine in Psoriatic Arthritis.
المؤلفون: Laborde CM; Dreamgenics, 33010 Oviedo, Spain., Larzabal L; Dreamgenics, 33010 Oviedo, Spain., González-Cantero Á; Department of Dermatology, Hospital Universitario Ramon y Cajal, 28034 Madrid, Spain.; Faculty of Medicine, Universidad Francisco de Vitoria, Ctra. Pozuelo-Majadahonda, 28223 Pozuelo de Alarcón, 28034 Madrid, Spain., Castro-Santos P; Immunology, Centro de Investigaciones Biomédicas (CINBIO), Universidad de Vigo, 36310 Vigo, Spain., Díaz-Peña R; Faculty of Health Sciences, Universidad Autónoma de Chile, Talca 3460000, Chile.
المصدر: Journal of personalized medicine [J Pers Med] 2022 Jan 03; Vol. 12 (1). Date of Electronic Publication: 2022 Jan 03.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101602269 Publication Model: Electronic Cited Medium: Print ISSN: 2075-4426 (Print) Linking ISSN: 20754426 NLM ISO Abbreviation: J Pers Med Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI AG, 2011-
مستخلص: Psoriatic arthritis (PsA) is a common type of inflammatory arthritis found in up to 40% of patients with psoriasis. Although early diagnosis is important for reducing the risk of irreversible structural damage, there are no adequate screening tools for this purpose, and there are no clear markers of predisposition to the disease. Much evidence indicates that PsA disorder is complex and heterogeneous, where genetic and environmental factors converge to trigger inflammatory events and the development of the disease. Nevertheless, the etiologic events that underlie PsA are complex and not completely understood. In this review, we describe the existing data in PsA in order to highlight the need for further research in this disease to progress in the knowledge of its pathobiology and to obtain early diagnosis tools for these patients.
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فهرسة مساهمة: Keywords: epigenomics; genome-wide association studies; genomics; personalized medicine; psoriatic arthritis; spondyloarthropathies; transcriptomics
تواريخ الأحداث: Date Created: 20220121 Latest Revision: 20220128
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC8780979
DOI: 10.3390/jpm12010035
PMID: 35055350
قاعدة البيانات: MEDLINE
الوصف
تدمد:2075-4426
DOI:10.3390/jpm12010035