دورية أكاديمية
Medication adherence in young adults with youth-onset type 2 diabetes: iCount, an observational study.
| العنوان: | Medication adherence in young adults with youth-onset type 2 diabetes: iCount, an observational study. |
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| المؤلفون: | Trief PM; State University of New York (SUNY) Upstate Medical University, 750 E. Adams St., Syracuse, NY 13210, USA. Electronic address: triefp@upstate.edu., Kalichman SC; University of Connecticut, 2006 Hillside Road, Storrs, CT 06269-1020, USA. Electronic address: seth.k@uconn.edu., Wang D; State University of New York (SUNY) Upstate Medical University, 750 E. Adams St., Syracuse, NY 13210, USA. Electronic address: wangd@upstate.edu., Drews KL; George Washington University, 6110 Executive Blvd., Rockville, MD 20852, USA. Electronic address: kdrews@bsc.gwu.edu., Anderson BJ; Baylor College of Medicine, 1102 Bates Ave., Houston, TX 77030, USA. Electronic address: bja@bcm.edu., Bulger JD; State University of New York (SUNY) Upstate Medical University, 750 E. Adams St., Syracuse, NY 13210, USA. Electronic address: bulgerj@upstate.edu., Weinstock RS; State University of New York (SUNY) Upstate Medical University, 750 E. Adams St., Syracuse, NY 13210, USA. Electronic address: weinstor@upstate.edu. |
| المصدر: | Diabetes research and clinical practice [Diabetes Res Clin Pract] 2022 Feb; Vol. 184, pp. 109216. Date of Electronic Publication: 2022 Jan 24. |
| نوع المنشور: | Journal Article; Observational Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Scientific Publishers Country of Publication: Ireland NLM ID: 8508335 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8227 (Electronic) Linking ISSN: 01688227 NLM ISO Abbreviation: Diabetes Res Clin Pract Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 1993- : Limerick : Elsevier Scientific Publishers Original Publication: Amsterdam : Elsevier Science Publishers B.V., c1985- |
| مواضيع طبية MeSH: | Diabetes Mellitus, Type 2*/drug therapy , Diabetes Mellitus, Type 2*/epidemiology, Adolescent ; Adult ; Blood Glucose ; Female ; Glycated Hemoglobin/analysis ; Hispanic or Latino ; Humans ; Hypoglycemic Agents/therapeutic use ; Insulin/therapeutic use ; Male ; Medication Adherence ; Young Adult |
| مستخلص: | Aims: To assess prevalence of, and factors associated with, medication adherence of young adults with youth-onset type 2 diabetes. Methods: Oral hypoglycaemia agent (OHA) adherence was measured with unannounced telephone pill counts, insulin adherence was self-reported. Those taking ≥ 80% of pills/insulin were classified "high-adherent," <80% of pills/insulin "low-adherent." Analyses included unadjusted, and adjusted linear and logistic regressions assessing associations of participant factors with adherence. Results: For people taking OHAs (N = 212, mean age 26 yrs, 67% women, 18% non-Hispanic White, 35% non-Hispanic Black, 41% Hispanic), 69.8% were low-adherent. HbA1c was lower in the high-adherent group (9.2%/77 mmol/mol vs. 10.0%/86 mmol/mol, p < 0.04). More non-Hispanic Blacks were low-adherent (85.7%) than Hispanics (60.2%) and non-Hispanic whites (55.3%, p < 0.002); 91.4% of participants without healthcare coverage were low-adherent vs. 65.5% of those with coverage (p < 0.004). After adjustment, gender (p = 0.024), race/ethnicity (p < 0.001) and healthcare coverage (p = 0.001) remained related to OHA adherence. For insulin (N = 192), 37% were low-adherent. HbA1c was associated with insulin adherence (low = 11.2%/99 mmol/mol vs. high = 10.0%/86 mmol/mol, p < 0.001) with and without adjustment. Conclusions: Young adults with youth-onset type 2 diabetes, especially females, non-Hispanic Blacks and those without healthcare coverage, commonly had low-OHA adherence. Glycaemic control was also poor. Interventions to improve medication adherence are needed for this vulnerable group. (Copyright © 2022 Elsevier B.V. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Adults; Ethnic differences; Insulin therapy; Oral therapies; Self-management; Type 2 diabetes |
| المشرفين على المادة: | 0 (Blood Glucose) 0 (Glycated Hemoglobin A) 0 (Hypoglycemic Agents) 0 (Insulin) |
| تواريخ الأحداث: | Date Created: 20220127 Date Completed: 20220310 Latest Revision: 20221207 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1016/j.diabres.2022.109216 |
| PMID: | 35085644 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1872-8227 |
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| DOI: | 10.1016/j.diabres.2022.109216 |