دورية أكاديمية
أعرض في EDS

Evaluation of the Viability of Untreated Leiomyomas Using Computed Tomography-Detected Calcification Patterns.

التفاصيل البيبلوغرافية
العنوان: Evaluation of the Viability of Untreated Leiomyomas Using Computed Tomography-Detected Calcification Patterns.
المؤلفون: Crane EP; From the Department of Radiology, Medstar Georgetown University Hospital, Washington, DC., Fenlon EP 3rd; Morgan Stanley Children's Hospital-New York Presbyterian Hospital, Columbia University Irving Medical Center, New York, NY., Ascher SM; From the Department of Radiology, Medstar Georgetown University Hospital, Washington, DC., Balaji D; Case Western Reserve School of Medicine, Cleveland Ohio., Siegelman ES; Department of Radiology, Hospital of the University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA.
المصدر: Journal of computer assisted tomography [J Comput Assist Tomogr] 2022 Jan-Feb 01; Vol. 46 (1), pp. 6-10.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 7703942 Publication Model: Print Cited Medium: Internet ISSN: 1532-3145 (Electronic) Linking ISSN: 03638715 NLM ISO Abbreviation: J Comput Assist Tomogr Subsets: MEDLINE
أسماء مطبوعة: Publication: <2000->: Hagerstown, MD : Lippincott Williams & Wilkins
Original Publication: New York, Raven Press.
مواضيع طبية MeSH: Calcinosis*/diagnostic imaging , Calcinosis*/etiology , Calcinosis*/pathology , Leiomyoma*/complications , Leiomyoma*/diagnostic imaging , Leiomyoma*/pathology , Uterine Neoplasms*/complications , Uterine Neoplasms*/diagnostic imaging , Uterine Neoplasms*/pathology, Female ; Humans ; Middle Aged ; Retrospective Studies ; Tomography, X-Ray Computed/methods ; Uterus/diagnostic imaging
مستخلص: Objective: To evaluate the relationship between computed tomography (CT)-detected calcification patterns and Magnetic Resonance Imaging (MRI) enhancement as a surrogate for viability in untreated uterine leiomyomas.
Methods: We queried 2 university hospital databases to identify patients with: (1) at least 1 calcified leiomyoma on CT greater than 1 cm (2) contrast-enhanced MRI of the pelvis performed within 5 years of the CT, and (3) no prior history of uterine fibroid embolization (UFE). Computed tomography was used to analyze calcification pattern and contrast-enhanced MRI to analyze size and viability.
Results: There were 12,862 reports that fit the criteria. After exclusion, 50 patients with 74 calcified untreated leiomyomas were analyzed. Three calcification patterns were identified: rim (n = 22), diffuse (n = 9), and coarse either less than or greater than 50% (n = 43). Four of 22 (18%) of leiomyomas with rim calcification were viable. Three of 9 (33%) of leiomyomas with diffuse calcification were viable. All leiomyomas with coarse calcifications were viable, 43 of 43 (100%).
Conclusions: Leiomyomas with coarse calcifications are viable, whereas the majority with rim or diffuse calcification are not. This information may be helpful when triaging symptomatic women to treatment.
Competing Interests: The authors declare no conflict of interest.
(Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.)
References: Zimmermann A, Bernuit D, Gerlinger C, et al. Prevalence, symptoms and management of uterine fibroids: an international internet-based survey of 21,746 women. BMC Womens Health. 2012;12:6.
Murase E, Siegelman ES, Outwater EK, et al. Uterine leiomyomas: histopathologic features, MR imaging findings, differential diagnosis, and treatment. Radiographics. 1999;19:1179–1197.
Casillas J, Joseph RC, Guerra JJ Jr. CT appearance of uterine leiomyomas. Radiographics. 1990;10:999–1007.
Fleischer A, Entman SS, Porrath, James AE, et al. The principles and practice of ultrasonography in obstetrics and gynecology. Sonographic evaluation of uterine malformations and disorders. 3rd ed. Norwalk: Appleton-Century-Crofts; 1985:531–568.
Verma SK, Gonsalves CF, Baltarowich OH, et al. Spectrum of imaging findings on MRI and CT after uterine artery embolization. Abdom Imaging. 2010;35:118–128.
Nicholson TA, Pelage JP, Ettles DF. Fibroid calcification after uterine artery embolization: ultrasonographic appearance and pathology. J Vasc Interv Radiol. 2001;12:443–446.
Ho VB, Allen SF, Hood MN, et al. Renal masses: quantitative assessment of enhancement with dynamic MR imaging. Radiology. 2002;224:695–700.
Johnson L. What Treatments are Available for My Calcified Fibroids? [Fibroid Treatment Collective] March 29, 2016; Available at: https://fibroids.com/blog/treatments-available-calcified-fibroids. Accessed February 20, 2019.
Ueda H, Togashi K, Konishi I, et al. Unusual appearances of uterine leiomyomas: MR imaging findings and their histopathologic backgrounds. Radiographics. 1999. 19 Spec No;S131–S145.
Bradley J, Quade SJR. In: Robboy GLM, Stanley J, Prat Jaime, Bently Rex C, et al, eds. Robboy's Pathology of the Female Reproductive Tract. 2nd ed. 2009.
Cirkel U, Ochs H, Roehl A, et al. Estrogen and progesterone receptor content of enucleated uterine myomata after luteinizing hormone-releasing hormone. Analogue depot therapy. Acta Obstet Gynecol Scand. 1994;73:328–332.
تواريخ الأحداث: Date Created: 20220131 Date Completed: 20220203 Latest Revision: 20220203
رمز التحديث: 20231215
DOI: 10.1097/RCT.0000000000001245
PMID: 35099130
قاعدة البيانات: MEDLINE
الوصف
تدمد:1532-3145
DOI:10.1097/RCT.0000000000001245