دورية أكاديمية
"It was an important part of my treatment": a qualitative study of Norwegian breast Cancer patients' experiences with mainstreamed genetic testing.
العنوان: | "It was an important part of my treatment": a qualitative study of Norwegian breast Cancer patients' experiences with mainstreamed genetic testing. |
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المؤلفون: | Strømsvik N; Department of Health and Caring Sciences, Western Norway University of Applied Sciences, Bergen, Norway. nina@tbt.no.; Northern Norway Familial Cancer Center, Department of Medical Genetics, University Hospital of North Norway, Tromsø, Norway. nina@tbt.no., Olsson P; Department of Surgery, Section of Breast and Endocrine Surgery, Innlandet Hospital, Hamar, Norway., Gravdehaug B; Department of Breast and Endocrine Surgery, Akershus University Hospital, Lørenskog, Norway., Lurås H; Health Services Research Unit, Akershus University Hospital, Lørenskog, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Schlichting E; Section for Breast and Endocrine Surgery, Department of Cancer, Oslo University Hospital, Oslo, Norway., Jørgensen K; Department of Medical Genetics, Oslo University Hospital, Oslo, Norway., Wangensteen T; Department of Medical Genetics, Oslo University Hospital, Oslo, Norway., Vamre T; Department of Medical Genetics, Oslo University Hospital, Oslo, Norway., Heramb C; Department of Medical Genetics, Oslo University Hospital, Oslo, Norway., Mæhle L; Department of Medical Genetics, Oslo University Hospital, Oslo, Norway., Grindedal EM; Department of Medical Genetics, Oslo University Hospital, Oslo, Norway. |
المصدر: | Hereditary cancer in clinical practice [Hered Cancer Clin Pract] 2022 Feb 05; Vol. 20 (1), pp. 6. Date of Electronic Publication: 2022 Feb 05. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: BioMed Central Country of Publication: Poland NLM ID: 101231179 Publication Model: Electronic Cited Medium: Print ISSN: 1731-2302 (Print) Linking ISSN: 17312302 NLM ISO Abbreviation: Hered Cancer Clin Pract Subsets: PubMed not MEDLINE |
أسماء مطبوعة: | Publication: 2008- : London : BioMed Central Original Publication: Poznań, Poland : Termedia Pub. House, 2003- |
مستخلص: | Background: In South-Eastern Norway, genetic testing for BRCA1 and BRCA2 is offered to breast cancer patients by their treating surgeon or oncologist. Genetic counselling from a geneticist or a genetic counsellor is offered only to those who test positive for a pathogenic variant or have a family history of cancer. This practice is termed "mainstreamed genetic testing". The aim of this study was to learn about patients' experience of this healthcare service. Methods: Qualitative in-depth interviews were conducted with 22 breast cancer patients who had been diagnosed during the first half of 2016 or 2017 at one regional and one university hospital and who had been offered testing by their treating physician. A six-phase thematic approach was used to analyse the data. Results: The participants had varied experiences of how and when testing was offered. Three main themes emerged from the analysis: 1. informational and communicational needs and challenges during a chaotic time, 2. the value of genetic testing and 3. the importance of standardised routines for mainstreamed genetic testing. Conclusions: Despite the shock of their diagnosis and the varying experiences they had in respect of how and when testing was offered, all of the participants emphasised that genetic testing had been an important part of their diagnosis and treatment. Our results indicate that there is a need for continuous collaboration between geneticists, surgeons, oncologists and laboratory specialists in order to establish simple and robust routines so as to ensure that all eligible breast cancer patients are offered testing at a point when the test result can have an impact on treatment. (© 2022. The Author(s).) |
References: | Gynecol Oncol. 2014 Aug;134(2):326-30. (PMID: 24910453) Clin Genet. 2010 Apr;77(4):350-4. (PMID: 19930416) Fam Cancer. 2019 Jul;18(3):293-301. (PMID: 30689103) Lancet. 2001 Aug 11;358(9280):483-8. (PMID: 11513933) Br J Cancer. 2014 Feb 18;110(4):1081-7. (PMID: 24423928) JAMA. 2017 Jun 20;317(23):2402-2416. (PMID: 28632866) J Clin Oncol. 2015 Jun 10;33(17):1895-901. (PMID: 25847929) J Med Libr Assoc. 2005 Jul;93(3):353-62. (PMID: 16059425) Psychooncology. 2007 Dec;16(12):1111-20. (PMID: 17345558) BMJ. 2014 Feb 11;348:g226. (PMID: 24519767) Eur J Cancer Care (Engl). 2005 Jul;14(3):272-81. (PMID: 15952973) J Genet Couns. 2010 Jun;19(3):228-34. (PMID: 20119700) J Genet Couns. 2018 May 11;:. (PMID: 29752676) Med J Aust. 1999 Oct 4;171(7):362-6. (PMID: 10590725) Gynecol Oncol. 2015 Jul;138(1):109-14. (PMID: 25933682) Fam Cancer. 2017 Apr;16(2):187-193. (PMID: 28120249) Fam Cancer. 2020 Apr;19(2):133-142. (PMID: 32002722) Genet Med. 2016 Feb;18(2):137-44. (PMID: 25905441) Future Oncol. 2019 Jul;15(20):2327-2335. (PMID: 31304797) J Psychosoc Oncol. 2011;29(4):450-73. (PMID: 21966727) J Clin Oncol. 2001 Apr 1;19(7):2049-56. (PMID: 11283138) Psychooncology. 1999 Mar-Apr;8(2):155-66. (PMID: 10335559) Ann Oncol. 2014 Jan;25(1):57-63. (PMID: 24276029) Cancer. 1995 Jul 15;76(2):167-77. (PMID: 8625088) Int J Gynecol Cancer. 2013 Mar;23(3):431-6. (PMID: 23354368) Support Care Cancer. 2012 Nov;20(11):2949-58. (PMID: 22441502) N Engl J Med. 2017 Aug 10;377(6):523-533. (PMID: 28578601) Int J Emerg Ment Health. 2000 Spring;2(2):119-25. (PMID: 11232174) J Surg Oncol. 2017 Dec;116(8):1029-1039. (PMID: 28703900) N Engl J Med. 2018 Aug 23;379(8):753-763. (PMID: 30110579) Support Care Cancer. 2015 Jul;23(7):2033-43. (PMID: 25524004) Eur J Hum Genet. 2016 Jun;24(6):881-8. (PMID: 26350514) Fam Cancer. 2013 Dec;12(4):675-82. (PMID: 23604858) |
معلومات مُعتمدة: | 194790-2017 Kreftforeningen |
فهرسة مساهمة: | Keywords: BRCA1, BRCA2; Breast cancer; Genetic testing for breast cancer; Mainstreamed genetic testing; Qualitative study |
تواريخ الأحداث: | Date Created: 20220206 Latest Revision: 20220216 |
رمز التحديث: | 20240628 |
مُعرف محوري في PubMed: | PMC8818154 |
DOI: | 10.1186/s13053-022-00212-6 |
PMID: | 35123550 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1731-2302 |
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DOI: | 10.1186/s13053-022-00212-6 |