دورية أكاديمية
أعرض في EDS

"It was an important part of my treatment": a qualitative study of Norwegian breast Cancer patients' experiences with mainstreamed genetic testing.

التفاصيل البيبلوغرافية
العنوان: "It was an important part of my treatment": a qualitative study of Norwegian breast Cancer patients' experiences with mainstreamed genetic testing.
المؤلفون: Strømsvik N; Department of Health and Caring Sciences, Western Norway University of Applied Sciences, Bergen, Norway. nina@tbt.no.; Northern Norway Familial Cancer Center, Department of Medical Genetics, University Hospital of North Norway, Tromsø, Norway. nina@tbt.no., Olsson P; Department of Surgery, Section of Breast and Endocrine Surgery, Innlandet Hospital, Hamar, Norway., Gravdehaug B; Department of Breast and Endocrine Surgery, Akershus University Hospital, Lørenskog, Norway., Lurås H; Health Services Research Unit, Akershus University Hospital, Lørenskog, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Schlichting E; Section for Breast and Endocrine Surgery, Department of Cancer, Oslo University Hospital, Oslo, Norway., Jørgensen K; Department of Medical Genetics, Oslo University Hospital, Oslo, Norway., Wangensteen T; Department of Medical Genetics, Oslo University Hospital, Oslo, Norway., Vamre T; Department of Medical Genetics, Oslo University Hospital, Oslo, Norway., Heramb C; Department of Medical Genetics, Oslo University Hospital, Oslo, Norway., Mæhle L; Department of Medical Genetics, Oslo University Hospital, Oslo, Norway., Grindedal EM; Department of Medical Genetics, Oslo University Hospital, Oslo, Norway.
المصدر: Hereditary cancer in clinical practice [Hered Cancer Clin Pract] 2022 Feb 05; Vol. 20 (1), pp. 6. Date of Electronic Publication: 2022 Feb 05.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: Poland NLM ID: 101231179 Publication Model: Electronic Cited Medium: Print ISSN: 1731-2302 (Print) Linking ISSN: 17312302 NLM ISO Abbreviation: Hered Cancer Clin Pract Subsets: PubMed not MEDLINE
أسماء مطبوعة: Publication: 2008- : London : BioMed Central
Original Publication: Poznań, Poland : Termedia Pub. House, 2003-
مستخلص: Background: In South-Eastern Norway, genetic testing for BRCA1 and BRCA2 is offered to breast cancer patients by their treating surgeon or oncologist. Genetic counselling from a geneticist or a genetic counsellor is offered only to those who test positive for a pathogenic variant or have a family history of cancer. This practice is termed "mainstreamed genetic testing". The aim of this study was to learn about patients' experience of this healthcare service.
Methods: Qualitative in-depth interviews were conducted with 22 breast cancer patients who had been diagnosed during the first half of 2016 or 2017 at one regional and one university hospital and who had been offered testing by their treating physician. A six-phase thematic approach was used to analyse the data.
Results: The participants had varied experiences of how and when testing was offered. Three main themes emerged from the analysis: 1. informational and communicational needs and challenges during a chaotic time, 2. the value of genetic testing and 3. the importance of standardised routines for mainstreamed genetic testing.
Conclusions: Despite the shock of their diagnosis and the varying experiences they had in respect of how and when testing was offered, all of the participants emphasised that genetic testing had been an important part of their diagnosis and treatment. Our results indicate that there is a need for continuous collaboration between geneticists, surgeons, oncologists and laboratory specialists in order to establish simple and robust routines so as to ensure that all eligible breast cancer patients are offered testing at a point when the test result can have an impact on treatment.
(© 2022. The Author(s).)
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معلومات مُعتمدة: 194790-2017 Kreftforeningen
فهرسة مساهمة: Keywords: BRCA1, BRCA2; Breast cancer; Genetic testing for breast cancer; Mainstreamed genetic testing; Qualitative study
تواريخ الأحداث: Date Created: 20220206 Latest Revision: 20220216
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC8818154
DOI: 10.1186/s13053-022-00212-6
PMID: 35123550
قاعدة البيانات: MEDLINE
الوصف
تدمد:1731-2302
DOI:10.1186/s13053-022-00212-6