دورية أكاديمية
أعرض في EDS

A fungal protease named AsES triggers antiviral immune responses and effectively restricts virus infection in arabidopsis and Nicotiana benthamiana plants.

التفاصيل البيبلوغرافية
العنوان: A fungal protease named AsES triggers antiviral immune responses and effectively restricts virus infection in arabidopsis and Nicotiana benthamiana plants.
المؤلفون: Caro MDP; Instituto de Agrobiotecnología y Biología Molecular (IABIMO), CICVyA, Instituto Nacional de Tecnología Agropecuaria (INTA), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), De los Reseros y N. Repetto s/n, Hurlingham B1686IGC, Argentina.; Estación Experimental Agropecuaria Famaillá, Instituto Nacional de Tecnología Agropecuaria (INTA), Ruta Provincial 301 Km 32, Tucumán, Argentina.; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina., Venturuzzi AL; Instituto de Agrobiotecnología y Biología Molecular (IABIMO), CICVyA, Instituto Nacional de Tecnología Agropecuaria (INTA), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), De los Reseros y N. Repetto s/n, Hurlingham B1686IGC, Argentina., Moschen S; Estación Experimental Agropecuaria Famaillá, Instituto Nacional de Tecnología Agropecuaria (INTA), Ruta Provincial 301 Km 32, Tucumán, Argentina.; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina., Salazar SM; Estación Experimental Agropecuaria Famaillá, Instituto Nacional de Tecnología Agropecuaria (INTA), Ruta Provincial 301 Km 32, Tucumán, Argentina., Díaz-Ricci JC; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina.; Instituto Superior de Investigaciones Biológicas (INSIBIO), CONICET-UNT, and Instituto de Química Biológica 'Dr. Bernabé Bloj', Facultad de Bioquímica, Química y Farmacia, UNT, San Miguel de Tucumán, Argentina., Asurmendi S; Instituto de Agrobiotecnología y Biología Molecular (IABIMO), CICVyA, Instituto Nacional de Tecnología Agropecuaria (INTA), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), De los Reseros y N. Repetto s/n, Hurlingham B1686IGC, Argentina.
المصدر: Annals of botany [Ann Bot] 2022 Apr 13; Vol. 129 (5), pp. 593-606.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0372347 Publication Model: Print Cited Medium: Internet ISSN: 1095-8290 (Electronic) Linking ISSN: 03057364 NLM ISO Abbreviation: Ann Bot Subsets: MEDLINE
أسماء مطبوعة: Publication: 2002- : Oxford, UK : Oxford University Press
Original Publication: Oxford [etc.]
مواضيع طبية MeSH: Arabidopsis*/genetics , Tobacco Mosaic Virus*/physiology , Virus Diseases*, Antiviral Agents/metabolism ; Immunity ; Peptide Hydrolases/metabolism ; Plant Diseases ; Salicylic Acid/metabolism ; Salicylic Acid/pharmacology ; Nicotiana/genetics
مستخلص: Background and Aims: Plants have evolved complex mechanisms to fight against pathogens. Among these mechanisms, pattern-triggered immunity (PTI) relies on the recognition of conserved microbe- or pathogen-associated molecular patterns (MAMPs or PAMPs, respectively) by membrane-bound receptors. Indeed, PTI restricts virus infection in plants and, in addition, BRI1-associated kinase 1 (BAK1), a central regulator of PTI, plays a role in antiviral resistance. However, the compounds that trigger antiviral defences, along with their molecular mechanisms of action, remain mostly elusive. Herein, we explore the role of a fungal extracellular subtilase named AsES in its capacity to trigger antiviral responses.
Methods: In this study, we obtained AsES by recombinant expression, and evaluated and characterized its capacity to trigger antiviral responses against Tobacco mosaic virus (TMV) by performing time course experiments, analysing gene expression, virus movement and callose deposition.
Key Results: The results of this study provide direct evidence that exogenous treatment with recombinant AsES increases a state of resistance against TMV infection, in both arabidopsis and Nicotiana benthamiana plants. Also, the antiviral PTI response exhibited by AsES in arabidopsis is mediated by the BAK1/SERK3 and BKK1/SERK4 co-receptors. Moreover, AsES requires a fully active salicylic acid (SA) signalling pathway to restrict the TMV movement by inducing callose deposition. Additionally, treatment with PSP1, a biostimulant based on AsES as the active compound, showed an increased resistance against TMV in N. benthamiana and tobacco plants.
Conclusions: AsES is a fungal serine protease which triggers antiviral responses relying on a conserved mechanism by means of the SA signalling pathway and could be exploited as an effective and sustainable biotechnology strategy for viral disease management in plants.
(© The Author(s) 2022. Published by Oxford University Press on behalf of the Annals of Botany Company. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
References: Trends Plant Sci. 2011 Jun;16(6):300-9. (PMID: 21482172)
PLoS One. 2013 Aug 05;8(8):e70289. (PMID: 23940555)
J Exp Bot. 2014 Mar;65(5):1229-40. (PMID: 24253197)
Mol Plant Pathol. 2015 Jun;16(5):529-40. (PMID: 25220680)
Mol Plant Microbe Interact. 2014 Jun;27(6):567-77. (PMID: 24450774)
New Phytol. 2015 Feb;205(3):1296-1307. (PMID: 25365924)
Cell Host Microbe. 2016 May 11;19(5):641-50. (PMID: 27173932)
Front Plant Sci. 2014 Dec 19;5:739. (PMID: 25566306)
Proc Natl Acad Sci U S A. 1996 Aug 6;93(16):8776-81. (PMID: 8710948)
Plant J. 2018 Feb;93(4):592-613. (PMID: 29266555)
Plant Physiol. 2007 Dec;145(4):1232-40. (PMID: 17720752)
Ann Bot. 2017 Mar 01;119(5):737-747. (PMID: 27941090)
Phytopathology. 2006 Mar;96(3):255-63. (PMID: 18944440)
BMC Plant Biol. 2014 Aug 03;14:210. (PMID: 25084837)
J Exp Bot. 2015 May;66(10):2839-56. (PMID: 25788732)
Plant Cell. 2001 Jul;13(7):1499-510. (PMID: 11449047)
Nature. 2021 Apr;592(7852):110-115. (PMID: 33692545)
Clin Chem. 2009 Apr;55(4):611-22. (PMID: 19246619)
Mol Plant Microbe Interact. 2013 Nov;26(11):1271-80. (PMID: 23902263)
J Proteomics. 2011 Mar 1;74(3):337-49. (PMID: 21130907)
Mol Plant Microbe Interact. 2010 Nov;23(11):1403-12. (PMID: 20687788)
Mol Plant Microbe Interact. 2018 Apr;31(4):403-409. (PMID: 29135338)
Plant Cell. 2013 May;25(5):1489-505. (PMID: 23709626)
Front Plant Sci. 2014 Nov 21;5:655. (PMID: 25484886)
Nature. 2016 Nov 23;539(7630):524-529. (PMID: 27882964)
Front Microbiol. 2015 Nov 09;6:1237. (PMID: 26617580)
Mol Plant Pathol. 2017 Aug;18(6):878-886. (PMID: 27301551)
Int J Mol Sci. 2019 May 23;20(10):. (PMID: 31126102)
Annu Rev Plant Biol. 2009;60:379-406. (PMID: 19400727)
Plant J. 2006 May;46(3):477-91. (PMID: 16623907)
Viruses. 2012 Oct 29;4(11):2578-97. (PMID: 23202495)
J Biol Chem. 2010 Mar 26;285(13):9444-9451. (PMID: 20103591)
J Exp Bot. 2021 May 4;72(10):3526-3539. (PMID: 33687058)
Plant Cell. 2013 Jun;25(6):2315-29. (PMID: 23749844)
Anal Biochem. 1976 May 7;72:248-54. (PMID: 942051)
Mol Plant Microbe Interact. 2018 Dec;31(12):1257-1270. (PMID: 29877166)
Phytochemistry. 2009 Sep;70(13-14):1560-70. (PMID: 19796781)
Curr Opin Virol. 2018 Oct;32:88-99. (PMID: 30388659)
Annu Rev Plant Biol. 2018 Apr 29;69:209-236. (PMID: 29489394)
Proc Natl Acad Sci U S A. 2019 Oct 15;116(42):21274-21284. (PMID: 31575745)
Mol Plant Microbe Interact. 2018 Jan;31(1):46-60. (PMID: 28635519)
Curr Opin Virol. 2016 Apr;17:32-38. (PMID: 26800310)
PLoS Pathog. 2013;9(6):e1003445. (PMID: 23818851)
Plant Dis. 2001 May;85(5):481-488. (PMID: 30823123)
FEMS Microbiol Lett. 2010 Dec;313(2):120-6. (PMID: 21062346)
Elife. 2016 Sep 29;5:. (PMID: 27685353)
J Microbiol Biotechnol. 2008 Jan;18(1):67-73. (PMID: 18239419)
Plant Biol (Stuttg). 2020 Nov;22(6):1030-1040. (PMID: 32757407)
Front Plant Sci. 2018 Jun 12;9:763. (PMID: 29946326)
Nat Rev Immunol. 2019 Jan;19(1):31-44. (PMID: 30301972)
Curr Issues Mol Biol. 2017;23:1-16. (PMID: 28154243)
Science. 1994 Nov 18;266(5188):1247-50. (PMID: 17810266)
J Exp Bot. 2018 Nov 26;69(22):5325-5339. (PMID: 30165704)
J Biol Chem. 2013 May 17;288(20):14098-14113. (PMID: 23530047)
Mol Plant Microbe Interact. 2012 Oct;25(10):1370-84. (PMID: 22712510)
Nature. 2021 Apr;592(7852):105-109. (PMID: 33692546)
Mol Plant Pathol. 2018 Apr;19(4):1017-1028. (PMID: 28524452)
Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):12217-22. (PMID: 17626179)
Sci Rep. 2016 Feb 03;6:20579. (PMID: 26838475)
Curr Opin Plant Biol. 2002 Aug;5(4):325-31. (PMID: 12179966)
PLoS Genet. 2011 Apr;7(4):e1002046. (PMID: 21593986)
Planta. 2012 Sep;236(3):765-79. (PMID: 22767200)
Plant Sci. 2015 Dec;241:120-7. (PMID: 26706064)
Int J Mol Sci. 2020 Jan 31;21(3):. (PMID: 32024003)
Nucleic Acids Res. 2001 May 1;29(9):e45. (PMID: 11328886)
Mol Plant Pathol. 2019 Sep;20(9):1191-1195. (PMID: 31094075)
Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):12157-62. (PMID: 17615233)
Mol Cell. 2021 Sep 2;81(17):3449-3467. (PMID: 34403694)
Sci Rep. 2016 May 18;6:26144. (PMID: 27189192)
Front Plant Sci. 2018 Jul 24;9:844. (PMID: 30087681)
Mol Plant Microbe Interact. 2010 May;23(5):558-65. (PMID: 20367464)
Planta. 2011 Feb;233(2):299-308. (PMID: 21046144)
New Phytol. 2016 Aug;211(3):1008-19. (PMID: 27030513)
BMC Plant Biol. 2016 Jan 13;16:15. (PMID: 26757721)
Nat Rev Genet. 2010 Aug;11(8):539-48. (PMID: 20585331)
Proc Natl Acad Sci U S A. 2016 May 10;113(19):E2740-9. (PMID: 27118842)
Mol Plant Pathol. 2020 Feb;21(2):147-159. (PMID: 31769595)
Science. 1993 Aug 6;261(5122):754-6. (PMID: 17757215)
Proc Natl Acad Sci U S A. 2013 May 21;110(21):E1963-71. (PMID: 23650359)
Nature. 2015 Apr 30;520(7549):679-82. (PMID: 25707794)
Nat Rev Immunol. 2016 Sep;16(9):537-52. (PMID: 27477127)
Mol Plant Microbe Interact. 2007 Jun;20(6):659-70. (PMID: 17555274)
PLoS One. 2015 Aug 03;10(8):e0134719. (PMID: 26237414)
Mol Plant Pathol. 2019 Sep;20(9):1203-1210. (PMID: 30942534)
Trends Plant Sci. 2016 Dec;21(12):1017-1033. (PMID: 27660030)
Virus Genes. 1998;16(2):173-6. (PMID: 9608662)
Mol Plant Microbe Interact. 2000 Oct;13(10):1139-44. (PMID: 11043475)
Annu Rev Cell Dev Biol. 2012;28:489-521. (PMID: 22559264)
Annu Rev Plant Biol. 2014;65:473-503. (PMID: 24579988)
J Virol Methods. 2000 Nov;90(2):135-42. (PMID: 11064114)
Plant Physiol. 2006 May;141(1):178-87. (PMID: 16531487)
New Phytol. 2016 Aug;211(3):1020-34. (PMID: 27120694)
Plant Cell Environ. 2021 May;44(5):1399-1416. (PMID: 33554358)
Trends Ecol Evol. 2004 Oct;19(10):535-44. (PMID: 16701319)
Front Microbiol. 2017 Jan 05;7:2139. (PMID: 28105028)
Plant J. 2021 May;106(4):896-912. (PMID: 33837606)
Plant Physiol. 2006 Jan;140(1):249-62. (PMID: 16377744)
Mol Plant Microbe Interact. 2021 Jan;34(1):3-14. (PMID: 33048599)
Nature. 2007 Jul 26;448(7152):497-500. (PMID: 17625569)
New Phytol. 2015 May;206(3):932-947. (PMID: 25623163)
Environ Sci Pollut Res Int. 2015 Feb;22(4):2935-44. (PMID: 25226839)
Cell. 2009 May 29;137(5):860-72. (PMID: 19490895)
Annu Rev Phytopathol. 2017 Aug 4;55:257-286. (PMID: 28617654)
Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14732-7. (PMID: 18799732)
Nucleic Acids Res. 2009 Apr;37(6):e45. (PMID: 19237396)
فهرسة مساهمة: Keywords: Tobacco mosaic virus (TMV); BAK1; BKK1; Protease; callose; plant immunity; salicylic acid (SA)
المشرفين على المادة: 0 (Antiviral Agents)
EC 3.4.- (Peptide Hydrolases)
O414PZ4LPZ (Salicylic Acid)
تواريخ الأحداث: Date Created: 20220208 Date Completed: 20220415 Latest Revision: 20231213
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC9007096
DOI: 10.1093/aob/mcac013
PMID: 35134835
قاعدة البيانات: MEDLINE
الوصف
تدمد:1095-8290
DOI:10.1093/aob/mcac013