دورية أكاديمية
Co-circulation of two SARS-CoV-2 variant strains within imported pet hamsters in Hong Kong.
| العنوان: | Co-circulation of two SARS-CoV-2 variant strains within imported pet hamsters in Hong Kong. |
|---|---|
| المؤلفون: | Kok KH; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.; bCentre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Hong Kong Special Administrative Region, People's Republic of China., Wong SC; Infection Control Team, Queen Mary Hospital, Hong Kong West Cluster, Hong Kong Special Administrative Region, People's Republic of China., Chan WM; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China., Wen L; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China., Chu AW; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China., Ip JD; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China., Lee LK; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region, People's Republic of China., Wong IT; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region, People's Republic of China., Lo HW; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region, People's Republic of China., Cheng VC; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.; Infection Control Team, Queen Mary Hospital, Hong Kong West Cluster, Hong Kong Special Administrative Region, People's Republic of China.; Department of Microbiology, Queen Mary Hospital, Hong Kong Special Administrative Region, People's Republic of China., Ho AY; Department of Pathology, Princess Margaret Hospital, Hong Kong Special Administrative Region, People's Republic of China., Lam BH; Department of Pathology, Princess Margaret Hospital, Hong Kong Special Administrative Region, People's Republic of China., Tse H; Department of Pathology, Hong Kong Children's Hospital, Hong Kong Special Administrative Region, People's Republic of China., Lung D; Department of Pathology, Queen Elizabeth Hospital, Hong Kong Special Administrative Region, People's Republic of China., Ng KNH; Centre for Health Protection, Department of Health, Hong Kong Special Administrative Region, People's Republic of China., Au AK; Centre for Health Protection, Department of Health, Hong Kong Special Administrative Region, People's Republic of China., Siu GK; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region, People's Republic of China., Yuen KY; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.; bCentre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Hong Kong Special Administrative Region, People's Republic of China.; Department of Microbiology, Queen Mary Hospital, Hong Kong Special Administrative Region, People's Republic of China. |
| المصدر: | Emerging microbes & infections [Emerg Microbes Infect] 2022 Dec; Vol. 11 (1), pp. 689-698. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101594885 Publication Model: Print Cited Medium: Internet ISSN: 2222-1751 (Electronic) Linking ISSN: 22221751 NLM ISO Abbreviation: Emerg Microbes Infect Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2019- : [Philadelphia, PA] : Taylor & Francis Original Publication: New York : NPG, 2012-2018. |
| مواضيع طبية MeSH: | COVID-19* , SARS-CoV-2*/genetics, Animals ; Cricetinae ; Hong Kong ; Humans ; Molecular Docking Simulation ; Spike Glycoprotein, Coronavirus/chemistry |
| مستخلص: | During the investigation of a pet shop outbreak of severe acute respiratory coronavirus 2 (SARS-CoV-2) with probable hamster-to-human transmission, the environmental and hamster samples in epidemiologically linked pet shops were found positive for SARS-CoV-2 Delta variant AY.127 strains which are phylogenetically closely related to patients and reported European strains. This interspecies' spill-over has triggered transmission in 58 patients epidemiologically linked to three pet shops. Incidentally, three dwarf hamsters imported from the Netherlands and centralized in a warehouse distributing animals to pet shops were positive for SARS-CoV-2 spike variant phylogenetically related to European B.1.258 strains from March 2020. This B.1.258 strain almost disappeared in July 2021. While no hamster-to-human transmission of B.1.258-like strain was found in this outbreak, molecular docking showed that its spike receptor-binding domain (RBD) has a similar binding energy to human ACE2 compared to that of Delta variant AY.127. Therefore, the potential of this B.1.258-related spike variant for interspecies jumping cannot be ignored. The co-circulation of B.1.258-related spike variants with Delta AY.127, which originated in Europe and was not previously found in Hong Kong, suggested that hamsters in our wholesale warehouse and retail pet shops more likely have acquired these viruses in the Netherlands or stopovers during delivery by aviation than locally. The risk of human-to-hamster reverse zoonosis by multiple SARS-CoV-2 variants leading to further adaptive spike mutations with subsequent transmission back to humans cannot be underestimated as an outbreak source of COVID-19. Testing imported pet animals susceptible to SARS-CoV-2 is warranted to prevent future outbreaks. |
| References: | Clin Microbiol Rev. 2015 Apr;28(2):465-522. (PMID: 25810418) Science. 2021 Jan 8;371(6525):172-177. (PMID: 33172935) Clin Infect Dis. 2021 Jul 1;73(1):137-142. (PMID: 32756996) Emerg Microbes Infect. 2020 Dec;9(1):221-236. (PMID: 31987001) N Engl J Med. 1974 Sep 19;291(12):610-2. (PMID: 4604712) Emerg Infect Dis. 2009 May;15(5):781-4. (PMID: 19402968) Clin Infect Dis. 2020 Dec 3;71(9):2428-2446. (PMID: 32215622) Nucleic Acids Res. 2000 Jan 1;28(1):235-42. (PMID: 10592235) Emerg Infect Dis. 1998 Jan-Mar;4(1):117-21. (PMID: 9452406) Clin Infect Dis. 2021 Sep 18;:. (PMID: 34536277) Bull World Health Organ. 1975;52(4-6):549-53. (PMID: 1085210) Virus Genes. 2021 Dec;57(6):556-560. (PMID: 34448987) Mol Biol Evol. 2020 May 1;37(5):1530-1534. (PMID: 32011700) EBioMedicine. 2021 Nov;73:103643. (PMID: 34689086) Clin Infect Dis. 2020 Nov 19;71(16):2139-2149. (PMID: 32472679) Trends Microbiol. 2013 Oct;21(10):544-55. (PMID: 23770275) Lancet Microbe. 2020 May;1(1):e14-e23. (PMID: 32835326) Clin Microbiol Rev. 2007 Oct;20(4):660-94. (PMID: 17934078) Rev Med Virol. 2007 Mar-Apr;17(2):67-91. (PMID: 17042030) Mol Biol Evol. 1987 Jul;4(4):406-25. (PMID: 3447015) Annu Rev Biochem. 2008;77:363-82. (PMID: 18410248) Clin Infect Dis. 2021 Sep 09;:. (PMID: 34498683) Euro Surveill. 2020 Jun;25(23):. (PMID: 32553059) Clin Infect Dis. 2022 Mar 02;:. (PMID: 35234870) PLoS One. 2014 Feb 26;9(2):e89309. (PMID: 24586679) Nucleic Acids Res. 2019 Jan 8;47(D1):D506-D515. (PMID: 30395287) Nature. 2020 Jul;583(7818):834-838. (PMID: 32408338) Cell Rep Med. 2020 Oct 20;1(7):100121. (PMID: 32984855) Nucleic Acids Res. 2004 Mar 19;32(5):1792-7. (PMID: 15034147) |
| فهرسة مساهمة: | Keywords: Animal; SARS-CoV-2; coronavirus; hamster; interspecies; transmission |
| المشرفين على المادة: | 0 (Spike Glycoprotein, Coronavirus) |
| SCR Organism: | SARS-CoV-2 variants |
| تواريخ الأحداث: | Date Created: 20220209 Date Completed: 20220301 Latest Revision: 20220304 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC8890519 |
| DOI: | 10.1080/22221751.2022.2040922 |
| PMID: | 35135441 |
| قاعدة البيانات: | MEDLINE |
PDF full text from Publisher 
Full Text Finder | تدمد: | 2222-1751 |
|---|---|
| DOI: | 10.1080/22221751.2022.2040922 |