دورية أكاديمية

Postnatal exposure to PM 2.5 and weight trajectories in early childhood.

التفاصيل البيبلوغرافية
العنوان: Postnatal exposure to PM 2.5 and weight trajectories in early childhood.
المؤلفون: Vanoli J; Department of Environmental Health, T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts.; Department of Statistics and Quantitative Methods, Universita degli Studi di Milano-Bicocca, Milan, Italy., Coull BA; Department of Biostatistics, T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts., Ettinger de Cuba S; Department of Pediatrics, School of Medicine, Boston University, Boston, Massachusetts., Fabian PM; Department of Environmental Health, School of Public Health, Boston University, Boston, Massachusetts., Carnes F; Department of Environmental Health, School of Public Health, Boston University, Boston, Massachusetts., Massaro MA; Department of Environmental Health, School of Public Health, Boston University, Boston, Massachusetts., Poblacion A; Department of Pediatrics, School of Medicine, Boston University, Boston, Massachusetts., Bellocco R; Department of Statistics and Quantitative Methods, Universita degli Studi di Milano-Bicocca, Milan, Italy.; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Kloog I; Department of Geography and Environmental Development, Ben-Gurion University of the Negev, Beer Sheva, Israel., Schwartz J; Department of Environmental Health, T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts.; Department of Epidemiology, T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts., Laden F; Department of Environmental Health, T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts.; Department of Epidemiology, T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Zanobetti A; Department of Environmental Health, T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts.
المصدر: Environmental epidemiology (Philadelphia, Pa.) [Environ Epidemiol] 2021 Dec 16; Vol. 6 (1), pp. e181. Date of Electronic Publication: 2021 Dec 16 (Print Publication: 2022).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Wolters Kluwer Country of Publication: United States NLM ID: 101719527 Publication Model: eCollection Cited Medium: Internet ISSN: 2474-7882 (Electronic) Linking ISSN: 24747882 NLM ISO Abbreviation: Environ Epidemiol Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Philadelphia, PA : Wolters Kluwer, [2017]-
مستخلص: Background: Inconsistent evidence has assessed the impact of air pollution exposure on children's growth trajectories. We investigated the role of 90-day average postnatal fine particulate matter (PM 2.5 ) exposures by estimating the magnitude of effects at different ages, and the change in child weight trajectory by categories of exposure.
Methods: We obtained weight values from electronic health records at each hospital visit (males = 1859, females = 1601) from birth to 6 years old children recruited into the Boston-based Children's HealthWatch cohort (2009-2014). We applied mixed models, adjusting for individual and maternal confounders using (1) varying-coefficient models allowing for smooth non-linear interaction between age and PM 2.5 , (2) factor-smooth interaction between age and PM 2.5 quartiles. Additionally, we stratified by sex and low birthweight (LBW) status (≤2500 g).
Results: Using varying-coefficient models, we found that PM 2.5 significantly modified the association between age and weight in males, with a positive association in children younger than 3 years and a negative association afterwards. In boys, for each 10 µg/m 3 increase in PM 2.5 we found a 2.6% increase (95% confidence interval = 0.8, 4.6) in weight at 1 year of age and a -0.6% (95% confidence interval = -3.9, 2.9) at 5 years. We found similar but smaller changes in females, and no differences comparing growth trajectories across quartiles of PM 2.5 . Most of the effects were in LBW children and null for normal birthweight children.
Conclusions: This study suggests that medium-term postnatal PM 2.5 may modify weight trajectories nonlinearly in young children, and that LBW babies are more susceptible than normal-weight infants.
Competing Interests: The authors declare that they have no conflicts of interest with regard to the content of this report.
(Copyright © 2021 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The Environmental Epidemiology. All rights reserved.)
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معلومات مُعتمدة: P30 ES000002 United States ES NIEHS NIH HHS; P50 MD010428 United States MD NIMHD NIH HHS; T32 ES007069 United States ES NIEHS NIH HHS
فهرسة مساهمة: Keywords: Children’s weight trajectories; Fine particulate matter; Low-income families; Postnatal exposure; Varying coefficient models
تواريخ الأحداث: Date Created: 20220216 Latest Revision: 20240229
رمز التحديث: 20240229
مُعرف محوري في PubMed: PMC8835545
DOI: 10.1097/EE9.0000000000000181
PMID: 35169661
قاعدة البيانات: MEDLINE
الوصف
تدمد:2474-7882
DOI:10.1097/EE9.0000000000000181