دورية أكاديمية
أعرض في EDS

Olfactory system and energy metabolism: a two-way street.

التفاصيل البيبلوغرافية
العنوان: Olfactory system and energy metabolism: a two-way street.
المؤلفون: Jovanovic P; Center for Neural Science and Medicine, Biomedical Sciences Department and Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, 127 South San Vicente Boulevard, Los Angeles, CA 90048, USA., Riera CE; Center for Neural Science and Medicine, Biomedical Sciences Department and Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, 127 South San Vicente Boulevard, Los Angeles, CA 90048, USA; Department of Neurology, Cedars-Sinai Medical Center, Movement Disorder Program, 127 South San Vicente Boulevard, Los Angeles, CA 90048, USA; David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA. Electronic address: Celine.riera@cshs.org.
المصدر: Trends in endocrinology and metabolism: TEM [Trends Endocrinol Metab] 2022 Apr; Vol. 33 (4), pp. 281-291. Date of Electronic Publication: 2022 Feb 14.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review
اللغة: English
بيانات الدورية: Publisher: Elsevier Science Pub. Co Country of Publication: United States NLM ID: 9001516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3061 (Electronic) Linking ISSN: 10432760 NLM ISO Abbreviation: Trends Endocrinol Metab Subsets: MEDLINE
أسماء مطبوعة: Original Publication: New York : Elsevier Science Pub. Co., [c1989-
مواضيع طبية MeSH: Energy Metabolism* , Olfactory Bulb*/physiology, Animals ; Energy Intake ; Homeostasis ; Humans ; Mammals ; Obesity ; Smell/physiology
مستخلص: Olfactory perception guides daily decisions regarding food consumption, social interactions, and predator avoidance in all mammalian species. Volatile inputs, comprising odorants and pheromones, are relayed to the olfactory bulb (OB) from nasal sensory neurons cells and transferred to secondary processing regions within the brain. Olfaction has recently been shown to shape homeostatic and maladaptive processes of energy intake and expenditure through neuronal circuits involving the medial basal hypothalamus. Reciprocally, gastrointestinal hormones, such as ghrelin and leptin, the secretion of which depends on satiety and adiposity levels, might also influence olfactory sensitivity to alter food-seeking behaviors. Here, in addition to reviewing recent updates on identifying these neuronal networks, we also discuss how bidirectional neurocircuits existing between olfactory and energy processing centers can become dysregulated during obesity.
Competing Interests: Declaration of interests The authors have no conflict of interest to disclose.
(Copyright © 2022 Elsevier Ltd. All rights reserved.)
فهرسة مساهمة: Keywords: arcuate nucleus; hormonal feedback; hypothalamus; olfaction; sensory perception; thermogenesis
تواريخ الأحداث: Date Created: 20220218 Date Completed: 20220427 Latest Revision: 20220427
رمز التحديث: 20240628
DOI: 10.1016/j.tem.2022.01.004
PMID: 35177346
قاعدة البيانات: MEDLINE
الوصف
تدمد:1879-3061
DOI:10.1016/j.tem.2022.01.004