دورية أكاديمية
Incidence of Deep Vein Thrombosis in Cerebral Palsy Following an Orthopaedic Surgical Event.
العنوان: | Incidence of Deep Vein Thrombosis in Cerebral Palsy Following an Orthopaedic Surgical Event. |
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المؤلفون: | Sees JP; Nemours/Alfred I. duPont Hospital for Children, Wilmington, DE., Maguire K, Prestowitz S, Rogers KJ, Miller F |
المصدر: | Journal of pediatric orthopedics [J Pediatr Orthop] 2022 May-Jun 01; Vol. 42 (5), pp. 285-288. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 8109053 Publication Model: Print Cited Medium: Internet ISSN: 1539-2570 (Electronic) Linking ISSN: 02716798 NLM ISO Abbreviation: J Pediatr Orthop Subsets: MEDLINE |
أسماء مطبوعة: | Publication: 2000- : Philadelphia : Lippincott Williams & Wilkins Original Publication: New York Ny : Raven Press |
مواضيع طبية MeSH: | Cerebral Palsy*/complications , Cerebral Palsy*/epidemiology , Orthopedic Procedures*/adverse effects , Superior Vena Cava Syndrome*/complications , Venous Thromboembolism*/epidemiology , Venous Thrombosis*/epidemiology , Venous Thrombosis*/etiology , Venous Thrombosis*/prevention & control, Child ; Humans ; Incidence ; Risk Factors |
مستخلص: | Purpose: The purpose of this study was to identify the incidence of venous thromboembolism (VTE) and characterize the demographics, comorbidities, and risk factors for patients with cerebral palsy (CP) having orthopaedic surgery. Methods: All patients diagnosed with CP who underwent an orthopaedic surgical procedure at one institution between 2008 and 2017 were identified. Diagnosis codes and associated patient events were recovered from the electronic medical record. Each VTE event was reviewed to ascertain an actual VTE episode related to a surgical event. Results: The review included 2583 orthopaedic surgical events in 1371 patients. Of the initial 88 cases identified, 28 cases had a deep thrombosis documented. Six cases of VTE occurred within 3 months following the surgical event. Three of these cases had thigh thrombosis, and 2 patients had upper arm thrombosis, and 1 patient had a superior vena cava thrombosis. On further workup, 5 of these 6 patients were identified as having a congenital hypercoagulable condition. Conclusions: VTE is a relatively rare occurrence after orthopaedic surgery in pediatric patients with CP, but when it occurs, a full hematologic workup for a congenital hypercoagulable condition is indicated. Based on the low incidence of thigh thrombosis, routine pharmacological or intermittent mechanical calf compression is not recommended. A careful clinical and family history should be performed to identify patients with possible genetic hypercoagulable conditions who would merit prophylaxis. Level of Evidence: Level IV. Competing Interests: The authors declare no conflicts of interest. (Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.) |
References: | Mahajerin A, Croteau SE. Epidemiology and risk assessment of pediatric venous thromboembolism. Front Pediatr. 2017;5:68. Meier KA, Clark E, Tarango C, et al. Venous thromboembolism in hospitalized adolescents: an approach to risk assessment and prophylaxis. Hosp Pediatr. 2015;5:44–51. Tormene D, Simioni P, Prandoni P, et al. The incidence of venous thromboembolism in thrombophilic children: a prospective cohort study. Blood. 2002;100:2403–2405. Ries MD, Wolff D, Shaul JA. Hip arthroplasty in mentally impaired patients. Clin Orthop Relat Res. 1994;308:146–154. Knaus A, Terjesen T. Proximal femoral resection arthroplasty for patients with cerebral palsy and dislocated hips: 20 patients followed for 1-6 years. Acta Orthop. 2009;80:32–36. Torres VM, Saddi VA. Systematic review: hereditary thrombophilia associated to pediatric strokes and cerebral palsy. J Pediatr (Rio J). 2015;91:22–29. Sebire G. Factor V Leiden as a cause of hemiplegic cerebral palsy, neonatal stroke, and placental thrombosis? Ann Neurol. 1998;44:426–427. Andrew M, David M, Adams M, et al. Venous thromboembolic complications (VTE) in children: first analyses of the Canadian registry of VTE. Blood. 1994;83:1251–1257. Stein PD, Kayali F, Olson RE. Incidence of venous thromboembolism in infants and children: data from the National Hospital Discharge Survey. J Pediatr. 2004;145:563–565. van Ommen CH, Heijboer H, Büller HR, et al. Venous thromboembolism in childhood: a prospective two-year registry in The Netherlands. J Pediatr. 2001;139:676–681. Georgopoulos G, Hotchkiss MS, McNair B, et al. Incidence of deep vein thrombosis and pulmonary embolism in the elective pediatric orthopaedic patient. J Pediatr Orthop. 2016;36:101–109. Murphy NA. Deep venous thrombosis as a result of hypotonia secondary to intrathecal baclofen therapy: a case report. Arch Phys Med Rehabil. 2002;83:1311–1312. Faustino EVS, Shabanova V, Pinto MG, et al. Epidemiology of lower extremity deep venous thrombosis in critically ill adolescents. J Pediatr. 2018;201:176.e2–183.e2. Biss T, Alikhan R, Payne J, et al. Venous thromboembolism occurring during adolescence. Arch Dis Child. 2016;101:427–432. Campello E, Spiezia L, Simioni P. Diagnosis and management of factor V Leiden. Expert Rev Hematol. 2016;9:1139–1149. Chima RS, Hanson SJ. Venous throboembolism in critical illness and trauma: pediatric perspectives. Front Pediatr. 2017;5:47. Ho KM, Tan JA. Stratified meta-analysis of intermittent pneumatic compression of the lower limbs to prevent venous thromboembolism in hospitalized patients. Circulation. 2013;128:1003–1020. |
تواريخ الأحداث: | Date Created: 20220218 Date Completed: 20220413 Latest Revision: 20220413 |
رمز التحديث: | 20240628 |
DOI: | 10.1097/BPO.0000000000002113 |
PMID: | 35180727 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1539-2570 |
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DOI: | 10.1097/BPO.0000000000002113 |