دورية أكاديمية

Effectiveness of face masks in blocking the transmission of SARS-CoV-2: A preliminary evaluation of masks used by SARS-CoV-2-infected individuals.

التفاصيل البيبلوغرافية
العنوان: Effectiveness of face masks in blocking the transmission of SARS-CoV-2: A preliminary evaluation of masks used by SARS-CoV-2-infected individuals.
المؤلفون: Mello VM; Viral Hepatitis Laboratory, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil., Eller CM; Biosafety Level 3 Facility (BSL-3), Oswaldo Cruz Foundation, Rio de Janeiro, Brazil., Salvio AL; COVID-19 Analytical Center, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil., Nascimento FF; COVID-19 Analytical Center, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil., Figueiredo CM; COVID-19 Analytical Center, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil., Silva ESRF; COVID-19 Analytical Center, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil., Sousa PSF; Viral Hepatitis Laboratory, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil., Costa PF; COVID-19 Analytical Center, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil., Paiva AAP; Flavivirus Laboratory, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil., Mares-Guias MAMM; Flavivirus Laboratory, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil., Lemos ERS; Hantavirosis and Rickettsiosis Laboratory, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil., Horta MAP; Biosafety Level 3 Facility (BSL-3), Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.
المصدر: PloS one [PLoS One] 2022 Feb 23; Vol. 17 (2), pp. e0264389. Date of Electronic Publication: 2022 Feb 23 (Print Publication: 2022).
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
أسماء مطبوعة: Original Publication: San Francisco, CA : Public Library of Science
مواضيع طبية MeSH: COVID-19/*diagnosis , Masks/*virology, Adult ; Aged ; Asymptomatic Diseases ; COVID-19/transmission ; COVID-19/virology ; Female ; Humans ; Male ; Middle Aged ; Nasopharynx/virology ; RNA, Viral/analysis ; RNA, Viral/metabolism ; Real-Time Polymerase Chain Reaction ; SARS-CoV-2/genetics ; SARS-CoV-2/isolation & purification ; Viral Load ; Young Adult
مستخلص: In 2019, a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is transmitted via the airborne route, caused a new pandemic namely, "coronavirus disease 2019" (COVID-19). Although the effectiveness of face masks to prevent the transmission of SARS-CoV-2 is debated, no study has evaluated the virus-blocking efficacy of masks used by patients. We aimed to evaluate this efficacy of masks used by SARS-CoV-2-infected individuals. Data, masks used, and nasopharyngeal swab samples were obtained from these patients. Forty-five paired samples of nasopharyngeal swabs and masks were obtained and processed; the majority of masks were woven. Viral RNAs were amplified using quantitative reverse-transcription polymerase chain reaction and detected only on the inner parts of masks. Median viral load (VL) values of swabs and masks were 1.954x106 and 2,51x103, respectively. Statistically, there was a difference of approximately 1000 RNA copies/mL between swabs and masks and no significant difference in VL values among different types of masks. There were statistically significant differences in VL values between men and women and between symptomatic and asymptomatic patients. Our findings suggest the blocking of virus transmission by different types of masks and reinforce the use of masks by both infected and non-infected individuals.
Competing Interests: The authors have declared that no competing interests exist.
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المشرفين على المادة: 0 (RNA, Viral)
تواريخ الأحداث: Date Created: 20220223 Date Completed: 20220307 Latest Revision: 20220307
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC8865648
DOI: 10.1371/journal.pone.0264389
PMID: 35196363
قاعدة البيانات: MEDLINE
الوصف
تدمد:1932-6203
DOI:10.1371/journal.pone.0264389