دورية أكاديمية
Evaluation of Free Available Chlorine of Sodium Hypochlorite When Admixed with 0.2% Chitosan: A Preliminary Study.
| العنوان: | Evaluation of Free Available Chlorine of Sodium Hypochlorite When Admixed with 0.2% Chitosan: A Preliminary Study. |
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| المؤلفون: | Rajachar PB; Department of Conservative Dentistry and Endodontics, KLE Society's Institute of Dental Sciences, Bengaluru, Karnataka, India, Phone: + 91 9449638113, email: drprashanthraj@gmail.com., Vidhya MS; Department of Conservative Dentistry and Endodontics, KLE Society's Institute of Dental Sciences, Bengaluru, Karnataka, India., Karale R; Department of Conservative Dentistry and Endodontics, KLE Society's Institute of Dental Sciences, Bengaluru, Karnataka, India., Govindaraju VK; Department of Conservative Dentistry and Endodontics, KLE Society's Institute of Dental Sciences, Bengaluru, Karnataka, India., Shetty NK; Faculty of Dental Science, MS Ramaiah University of Applied Science, Bengaluru, Karnataka, India. |
| المصدر: | The journal of contemporary dental practice [J Contemp Dent Pract] 2021 Oct 01; Vol. 22 (10), pp. 1171-1174. Date of Electronic Publication: 2021 Oct 01. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Jaypee Brothers Medical Publishers Country of Publication: India NLM ID: 101090552 Publication Model: Electronic Cited Medium: Internet ISSN: 1526-3711 (Electronic) Linking ISSN: 15263711 NLM ISO Abbreviation: J Contemp Dent Pract Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2011- : [New Delhi] : Jaypee Brothers Medical Publishers Original Publication: [Cincinnati, OH] : Procter & Gamble Co., [1999- |
| مواضيع طبية MeSH: | Chitosan* , Smear Layer*, Chlorine ; Edetic Acid ; Humans ; Root Canal Irrigants/chemistry ; Sodium Hypochlorite |
| مستخلص: | Aim and Objective: The aim of the study was to evaluate the changes in free available chlorine (FAC) when 6% sodium hypochlorite (NaOCl) is admixed with irrigants 17% ethylenediaminetetraacetic acid (EDTA), 2% chlorhexidine (CHX), and 0.2% chitosan in varying proportions of 90:10, 80:20, and 50:50. Materials and Methods: The 25 mL aliquots of 6% NaOCl were admixed in varying proportions of 90:10, 80:20, and 50:50 with secondary irrigation solutions: (a) 17% EDTA, (b) 2% CHX, (c) 0.2% chitosan. Iodometric titration was done to evaluate the change in FAC. Statistical Analysis Used: Kruskal-Wallis and Mann-Whitney tests. Results: On titration, the mean FAC value of NaOCl at baseline was 1.99 g%. On mixing NaOCl with EDTA, the FAC decreased in all the three proportions and the values were 0.17 g%, 0.17 g%, and 0.06 g% at 90:10, 80:20, and 50:50 ratios, respectively. pH obtained was 9.55 at 50:50 ratio. On mixing NaOCl with CHX, FAC reduced and the values were 1.84 g%, 1.72 g%, and 0.27 g% at 90:10, 80:20, and 50:50 ratios, respectively. pH obtained was 10.87 at 50:50 ratio. On mixing NaOCl and chitosan, the FAC remained unaltered in all the three proportions and the values were 1.64 g%, 1.51 g%, and 1.63 g% at 90:10, 80:20, and 50:50 ratios, respectively. pH obtained was 11 at 50:50 ratio. Conclusion: Combination of NaOCl and chitosan did not lead to a reduction in FAC and the pH of the solution remained unaltered, suggesting that tissue-dissolving property of NaOCl might be preserved. Clinical Significance: The combination of chitosan with NaOCl is advantageous in two ways. Firstly, FAC remained unaltered and the pH of the solution was also maintained at 11.05 indicating that the tissue-dissolving property of NaOCl prevailed. Secondly, chitosan is known for its chelating property and is effective in smear layer removal. With further in vivo and in vitro studies, a combination of chitosan and NaOCl can be proposed as a novel irrigant. |
| فهرسة مساهمة: | Keywords: Chitosan; Chlorhexidine; Ethylenediaminetetraacetic acid; Free available chlorine; Iodometric titration Sodium hypochlorite. |
| المشرفين على المادة: | 0 (Root Canal Irrigants) 4R7X1O2820 (Chlorine) 9012-76-4 (Chitosan) 9G34HU7RV0 (Edetic Acid) DY38VHM5OD (Sodium Hypochlorite) |
| تواريخ الأحداث: | Date Created: 20220224 Date Completed: 20220225 Latest Revision: 20220225 |
| رمز التحديث: | 20240628 |
| PMID: | 35197386 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1526-3711 |
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