دورية أكاديمية
High proportions of rectal and pharyngeal chlamydia and gonorrhoea cases among cisgender men are missed using current CDC screening recommendations.
| العنوان: | High proportions of rectal and pharyngeal chlamydia and gonorrhoea cases among cisgender men are missed using current CDC screening recommendations. |
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| المؤلفون: | Assaf RD; Health Services, Los Angeles LGBT Center, Los Angeles, California, USA rassaf@lalgbtcenter.org.; Epidemiology, University of California Los Angeles Jonathan and Karin Fielding School of Public Health, Los Angeles, California, USA., Cunningham NJ; Health Services, Los Angeles LGBT Center, Los Angeles, California, USA., Adamson PC; Division of Infectious Diseases, David Geffen School of Medicine, Los Angeles, California, USA., Jann JT; Health Services, Los Angeles LGBT Center, Los Angeles, California, USA., Bolan RK; Health Services, Los Angeles LGBT Center, Los Angeles, California, USA. |
| المصدر: | Sexually transmitted infections [Sex Transm Infect] 2022 Dec; Vol. 98 (8), pp. 586-591. Date of Electronic Publication: 2022 Feb 25. |
| نوع المنشور: | Journal Article; Research Support, N.I.H., Extramural |
| اللغة: | English |
| بيانات الدورية: | Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 9805554 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1472-3263 (Electronic) Linking ISSN: 13684973 NLM ISO Abbreviation: Sex Transm Infect Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: London : BMJ Pub. Group, c1998- |
| مواضيع طبية MeSH: | Gonorrhea*/diagnosis , Gonorrhea*/epidemiology , Chlamydia Infections*/diagnosis , Chlamydia Infections*/epidemiology, Humans ; Female ; Male ; United States/epidemiology ; Neisseria gonorrhoeae/genetics ; Cross-Sectional Studies ; Nucleic Acid Amplification Techniques ; Chlamydia trachomatis/genetics ; Mass Screening ; Prevalence ; Centers for Disease Control and Prevention, U.S. ; Homosexuality, Male |
| مستخلص: | Objectives: Pharyngeal and rectal Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections are often undiagnosed due to their asymptomatic nature. This study aims to determine (1) the prevalence of CT/NG infections by anatomical site among cisgender men; (2) the proportion of missed CT/NG rectal/pharyngeal infections if urogenital testing alone was performed or screening depended on self-reported behaviour alone; and (3) the predictive probability of self-reported behaviours for rectal CT/NG. Methods: This cross-sectional study used electronic health records collected at a sexual health clinic in Los Angeles from 18 November 2018 until 28 February 2020. The included patients were ≥18 years of age cisgender men who received CT/NG testing at least once during the study period. We calculated the proportion of missed pharyngeal/rectal CT/NG infections if only urogenital testing had been done and if testing was based only on self-reported anal sex. Separately, we ran logistic regressions for predictive probability of self-reported anal sex on CT/NG rectal infections. Results: Overall, there were 13 476 unique patients with 26 579 visits. The prevalence of any extragenital CT/NG infection was 37.28%. Over 80% rectal/pharyngeal CT cases and over 65% rectal/pharyngeal NG cases would be missed if urogenital testing alone was performed. Likewise, over 35% rectal CT/NG cases would be missed had testing relied on self-reported sexual behaviours alone. Conclusions: The proportion of missed rectal and pharyngeal CT/NG infections is high. Our data from a sexual health clinic lend support to three-site opt-out testing for cisgender men attending a sexual health/Lesbian, Gay, Bisexual, Transgender, Queer/Questioning (LGBTQ+) specialty clinic regardless of their sexual orientation or reported sexual behaviours. Competing Interests: Competing interests: None declared. (© Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ.) |
| معلومات مُعتمدة: | K01 TW012170 United States TW FIC NIH HHS; T32 MH080634 United States MH NIMH NIH HHS |
| فهرسة مساهمة: | Keywords: Chlamydia trachomatis; Neisseria gonorrhoeae; epidemiology; men; sexual health |
| تواريخ الأحداث: | Date Created: 20220226 Date Completed: 20221121 Latest Revision: 20231202 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC9402804 |
| DOI: | 10.1136/sextrans-2021-055361 |
| PMID: | 35217590 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1472-3263 |
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| DOI: | 10.1136/sextrans-2021-055361 |