دورية أكاديمية
Hyperglycemia and Cytopenias as Signs of SARS-CoV-2 Delta Variant Infection in Preterm Infants.
| العنوان: | Hyperglycemia and Cytopenias as Signs of SARS-CoV-2 Delta Variant Infection in Preterm Infants. |
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| المؤلفون: | Boly TJ; Stead Family Department of Pediatrics, University of Iowa, Iowa City, Iowa., Reyes-Hernandez ME; Stead Family Department of Pediatrics, University of Iowa, Iowa City, Iowa., Daniels EC; Stead Family Department of Pediatrics, University of Iowa, Iowa City, Iowa., Kibbi N; Stead Family Department of Pediatrics, University of Iowa, Iowa City, Iowa., Bermick JR; Stead Family Department of Pediatrics, University of Iowa, Iowa City, Iowa.; Iowa Inflammation Program, University of Iowa, Iowa City, Iowa., Elgin TG; Stead Family Department of Pediatrics, University of Iowa, Iowa City, Iowa. |
| المصدر: | Pediatrics [Pediatrics] 2022 Jun 01; Vol. 149 (6). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: American Academy of Pediatrics Country of Publication: United States NLM ID: 0376422 Publication Model: Print Cited Medium: Internet ISSN: 1098-4275 (Electronic) Linking ISSN: 00314005 NLM ISO Abbreviation: Pediatrics Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Elk Grove Village Il : American Academy of Pediatrics Original Publication: Springfield, Ill., Thomas. |
| مواضيع طبية MeSH: | COVID-19*/diagnosis , Hyperglycemia*/diagnosis , Leukopenia* , Pregnancy Complications, Infectious*/diagnosis , Premature Birth*/epidemiology , Thrombocytopenia*, Adult ; Female ; Humans ; Infant ; Infant, Newborn ; Infant, Premature ; Infectious Disease Transmission, Vertical ; Pregnancy ; Pregnancy Outcome/epidemiology ; SARS-CoV-2 |
| مستخلص: | Information regarding severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in premature infants remains limited. Early in the pandemic, several studies reported that the risk of infection in infants was relatively small and that affected infants had a milder disease than what was seen in adults. Since the increase of the delta variant (SARS-CoV-2 B.1.617.2) within the population, there have been increased reports of more severe disease in infants. We present 3 cases of premature, very low birth weight infants with confirmed SARS-CoV-2 infection who presented with significant hyperglycemia and bone marrow dysfunction. Two infants had presumed vertical transmission, and 1 infant was infected by respiratory transmission. Despite the mode of transmission, symptom onset and duration were similar in all infants. All resolved with symptomatic management. In the context of the continuing pandemic, evaluation for SARS-CoV-2 infection should be considered in premature very low birth weight infants who demonstrate certain patterns of acute metabolic and hematologic abnormalities. (Copyright © 2022 by the American Academy of Pediatrics.) |
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| معلومات مُعتمدة: | T32 AI007343 United States AI NIAID NIH HHS |
| SCR Organism: | SARS-CoV-2 variants |
| تواريخ الأحداث: | Date Created: 20220303 Date Completed: 20220602 Latest Revision: 20230505 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC10158391 |
| DOI: | 10.1542/peds.2021-055331 |
| PMID: | 35237826 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1098-4275 |
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| DOI: | 10.1542/peds.2021-055331 |