دورية أكاديمية
Obesity and COVID-19 in-hospital fatality in southern Brazil: impact by age and skin color.
| العنوان: | Obesity and COVID-19 in-hospital fatality in southern Brazil: impact by age and skin color. |
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| المؤلفون: | Houvèssou GM; Universidade Federal de Pelotas. Faculdade de Medicina. Programa de Pós-Graduação em Epidemiologia. Pelotas, RS, Brasil., Leventhal DGP; Universidade Federal de Pelotas. Faculdade de Medicina. Programa de Pós-Graduação em Epidemiologia. Pelotas, RS, Brasil., Silva EVD; Universidade Federal de Pelotas. Faculdade de Medicina. Programa de Pós-Graduação em Epidemiologia. Pelotas, RS, Brasil.; Centro de Vigilância em Saúde do Estado do Rio Grande do Sul. Porto Alegre, RS, Brasil. |
| المصدر: | Revista de saude publica [Rev Saude Publica] 2022 Feb 23; Vol. 56, pp. 4. Date of Electronic Publication: 2022 Feb 23 (Print Publication: 2022). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Universidade De Sao Paulo. Faculdade De Higiene E Saude Publica Country of Publication: Brazil NLM ID: 0135043 Publication Model: eCollection Cited Medium: Internet ISSN: 1518-8787 (Electronic) Linking ISSN: 00348910 NLM ISO Abbreviation: Rev Saude Publica Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Sao Paulo : Universidade De Sao Paulo. Faculdade De Higiene E Saude Publica |
| مواضيع طبية MeSH: | COVID-19*, Adolescent ; Adult ; Brazil/epidemiology ; Hospitalization ; Hospitals ; Humans ; Male ; Middle Aged ; Obesity/complications ; Obesity/epidemiology ; Retrospective Studies ; Risk Factors ; SARS-CoV-2 ; Skin Pigmentation ; Young Adult |
| مستخلص: | Objectives: To estimate the relative risk (RR) of death associated with obesity, the attributable fraction in the exposed/with obesity (AFo), and the hospitalized population attributable risk (hospitalized PAR) associated with obesity of death among all adults and among Black and non-Black adults hospitalized for severe COVID-19 in the state of Rio Grande do Sul, Brazil. Methods: This retrospective cohort study of prognostic factors analyzed all cases of adults hospitalized for severe COVID-19 in the state of Rio Grande do Sul, Brazil. The occurrence of obesity was measured using secondary data from hospital teams' surveillance records. The outcome assessed was hospital deaths caused by severe COVID-19. Poisson regression was used to estimate RRs and 95% confidence intervals (95%CI). Results: The study sample consisted of 100,099 patients hospitalized for severe COVID-19, most of whom were White (84.7%) and male (54.7%). The effect of obesity was strongly modified by age, being higher in younger age groups. For the 18-39-year-old age group, RR = 2.54 (95%CI: 2.33-2.77), and in individuals 70 years and above, RR = 1.09 (95%CI: 1.05-1.13). For the 18-39-year-old age range, AFo = 60.6% and AFo = 42.5% in individuals 40-59 years old. For all hospitalizations, Hospitalized PAR measuring obesity for individuals 18-39 years old was 25.3%, while in the 40-59-year-old range, the hospitalized PAR = 11.2%. The hospitalized PAR was 31.7% in the Black population aged 18-39 years and 24.8% in non-Blacks. The hospitalized PAR was also larger in Blacks aged 40-59 years. Conclusions: Obesity largely impacted in-hospital case-fatality rates among young adults and Black people contaminated by COVID-19. These data highlight the extent of the risk concerning obesity, a highly prevalent chronic condition. |
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| تواريخ الأحداث: | Date Created: 20220303 Date Completed: 20220307 Latest Revision: 20220307 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC8849284 |
| DOI: | 10.11606/s1518-8787.2022056004329 |
| PMID: | 35239926 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1518-8787 |
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| DOI: | 10.11606/s1518-8787.2022056004329 |