دورية أكاديمية
Dihydrophenanthrenes and phenanthrenes from Dendrobium terminale .
| العنوان: | Dihydrophenanthrenes and phenanthrenes from Dendrobium terminale . |
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| المؤلفون: | Cheng L; Key Laboratory of Basic Pharmacology of Guizhou Province and School of Pharmacy, Zunyi Medical University, Zunyi, China.; Department of Pharmacy, The First People's Hospital of Bijie, Bijie, China., Fang YK; Key Laboratory of Basic Pharmacology of Guizhou Province and School of Pharmacy, Zunyi Medical University, Zunyi, China., Zhang MS; Key Laboratory of Basic Pharmacology of Guizhou Province and School of Pharmacy, Zunyi Medical University, Zunyi, China., Gang Wang; Key Laboratory of Basic Pharmacology of Guizhou Province and School of Pharmacy, Zunyi Medical University, Zunyi, China., Dong MJ; Key Laboratory of Basic Pharmacology of Guizhou Province and School of Pharmacy, Zunyi Medical University, Zunyi, China., Sun CX; Key Laboratory of Basic Pharmacology of Guizhou Province and School of Pharmacy, Zunyi Medical University, Zunyi, China., Xiao SJ; Key Laboratory of Basic Pharmacology of Guizhou Province and School of Pharmacy, Zunyi Medical University, Zunyi, China.; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medcial University, Guiyang, China.; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, China. |
| المصدر: | Natural product research [Nat Prod Res] 2023 Jul; Vol. 37 (14), pp. 2375-2382. Date of Electronic Publication: 2022 Mar 04. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Taylor & Francis Health Sciences Country of Publication: England NLM ID: 101167924 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-6427 (Electronic) Linking ISSN: 14786419 NLM ISO Abbreviation: Nat Prod Res Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Milton Park, UK : Taylor & Francis Health Sciences, c2003- |
| مواضيع طبية MeSH: | Dendrobium*/chemistry , Phenanthrenes*/pharmacology , Phenanthrenes*/chemistry, Plant Extracts/chemistry ; Magnetic Resonance Spectroscopy ; Cell Line, Tumor ; Molecular Structure |
| مستخلص: | Two previously undescribed dihydrophenanthrene derivatives ( 1 and 2 ) were isolated along with twelve known analogues from the whole plant of Dendrobium terminale . The structures of the new compounds were elucidated on the basis of detailed spectroscopic analysis. The NMR data of known phenanthrene derivatives ( 7 and 9 ) were revised by 2D NMR. The isolated compounds were evaluated for cytotoxicity against three kinds of tumor cell lines (sw1990, HCT-116, and HepG2). Especially compounds 11 and 14 showed stronger antitumor effects, and the structure-activity relationship of these compounds was discussed. |
| فهرسة مساهمة: | Keywords: Dendrobium terminale; cytotoxicity; dihydrophenanthrene; phenanthrene |
| المشرفين على المادة: | 0 (Phenanthrenes) 0 (Plant Extracts) |
| تواريخ الأحداث: | Date Created: 20220304 Date Completed: 20230615 Latest Revision: 20230615 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1080/14786419.2022.2048379 |
| PMID: | 35245427 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1478-6427 |
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| DOI: | 10.1080/14786419.2022.2048379 |