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mHealth Intervention to Improve Treatment Outcomes Among People With HIV Who Use Cocaine: Protocol for a Pilot Randomized Controlled Trial.

التفاصيل البيبلوغرافية
العنوان: mHealth Intervention to Improve Treatment Outcomes Among People With HIV Who Use Cocaine: Protocol for a Pilot Randomized Controlled Trial.
المؤلفون: Ranjit YS; Department of Communication, University of Missouri, Columbia, MO, United States., Krishnan A, Ghosh D; Department of Geography, University of Connecticut, Storrs, CT, United States., Cravero C; Harvard T H Chan School of Public Health, Harvard University, Boston, MA, United States., Zhou X; Department of Internal Medicine, Section of Infectious Diseases, Yale University, New Haven, CT, United States., Altice FL; Department of Internal Medicine, Section of Infectious Diseases, Yale University, New Haven, CT, United States.
المصدر: JMIR research protocols [JMIR Res Protoc] 2022 Mar 07; Vol. 11 (3), pp. e28332. Date of Electronic Publication: 2022 Mar 07.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: JMIR Publications Country of Publication: Canada NLM ID: 101599504 Publication Model: Electronic Cited Medium: Print ISSN: 1929-0748 (Print) Linking ISSN: 19290748 NLM ISO Abbreviation: JMIR Res Protoc Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Toronto : JMIR Publications
مستخلص: Background: Antiretroviral therapy is effective in reducing HIV-related morbidity, mortality, and transmission among people with HIV. However, adherence and persistence to antiretroviral therapy are crucial for successful HIV treatment outcomes. People with HIV who use cocaine have poor access to HIV services and lower retention in care.
Objective: The primary goal of this paper is to provide a detailed description of a mobile health intervention. This study is designed to improve medication adherence among people with HIV who use cocaine. A secondary goal is to list the important challenges and adaptations incorporated in the study design.
Methods: This study, titled Project SMART, used a wireless technology-based intervention, including cellular-enabled electronic pillboxes called TowerView Health and smartphones, to provide reminders and feedback on adherence behavior. The intervention design was based on the theoretical frameworks provided by the self-determination theory and the Motivation Technology Model. The 12-week pilot randomized controlled trial with four arms provided three types of feedback: automated feedback, automated+clinician feedback, and automated feedback+social network feedback.
Results: The study was funded by the National Institute of Drug Abuse (R21DA039842) on August 1, 2016. The institutional review board for the study was approved by Yale University on March 21, 2017. Data collection lasted from June 2017 to January 2020. The final enrollment was 71 participants, of whom 57 (80%) completed the study. The data are currently undergoing analysis, and the manuscript is being developed for publication in early 2022.
Conclusions: Implementing complex mobile health interventions for high-risk and marginalized populations with multicomponent interventions poses certain challenges, such as finding companies with adequate technology for clients and financial stability and minimizing the research-related burden for the study population. Conducting feasibility studies is important to recognize these challenges and the opportunity to address these challenges with solutions while keeping the design of a randomized controlled trial as true as possible.
Trial Registration: Clinicaltrials.gov NCT04418076; https://clinicaltrials.gov/ct2/show/NCT04418076.
International Registered Report Identifier (irrid): DERR1-10.2196/28332.
(©Yerina S Ranjit, Archana Krishnan, Debarchana Ghosh, Claire Cravero, Xin Zhou, Frederick L Altice. Originally published in JMIR Research Protocols (https://www.researchprotocols.org), 07.03.2022.)
التعليقات: Erratum in: JMIR Res Protoc. 2022 Apr 7;11(4):e37925. (PMID: 35389873)
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معلومات مُعتمدة: UL1 TR001863 United States TR NCATS NIH HHS
فهرسة مساهمة: Keywords: antiretroviral therapy; cocaine use; description of feasibility and acceptability; mHealth intervention; mobile phone; people with HIV; smart pillbox; smartphone
سلسلة جزيئية: ClinicalTrials.gov NCT04418076
تواريخ الأحداث: Date Created: 20220307 Latest Revision: 20220409
رمز التحديث: 20240829
مُعرف محوري في PubMed: PMC8938831
DOI: 10.2196/28332
PMID: 35254270
قاعدة البيانات: MEDLINE
الوصف
تدمد:1929-0748
DOI:10.2196/28332