دورية أكاديمية
Delayed haemolytic transfusion reaction due to Kidd antibodies.
| العنوان: | Delayed haemolytic transfusion reaction due to Kidd antibodies. |
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| المؤلفون: | Deb J; Department of Transfusion Medicine and Blood Bank, AIIMS Rishikesh, Rishikesh 249203, India., Kaur D; Department of Transfusion Medicine and Blood Bank, AIIMS Rishikesh, Rishikesh 249203, India. Electronic address: docdaljit@gmail.com., Sil S; Department of Transfusion Medicine and Blood Bank, AIIMS Rishikesh, Rishikesh 249203, India., Bava D; Department of Transfusion Medicine and Blood Bank, AIIMS Rishikesh, Rishikesh 249203, India., Mohan KA; Department of Transfusion Medicine and Blood Bank, AIIMS Rishikesh, Rishikesh 249203, India., Jain A; Department of Transfusion Medicine and Blood Bank, AIIMS Rishikesh, Rishikesh 249203, India., Negi G; Department of Transfusion Medicine and Blood Bank, AIIMS Rishikesh, Rishikesh 249203, India. |
| المصدر: | Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine [Transfus Clin Biol] 2022 Aug; Vol. 29 (3), pp. 269-272. Date of Electronic Publication: 2022 Mar 11. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Science Country of Publication: France NLM ID: 9423846 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1953-8022 (Electronic) Linking ISSN: 12467820 NLM ISO Abbreviation: Transfus Clin Biol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Paris : Elsevier Science Original Publication: Paris : Arnette Blackwell, c1994- |
| مواضيع طبية MeSH: | Transfusion Reaction*/etiology, Hemoglobins ; Hemolysis ; Humans ; Isoantibodies |
| مستخلص: | A delayed haemolytic transfusion reaction (DHTR) encompasses a positive direct antiglobulin test (DAT) developed anytime between 24 hours to 28days after cessation of transfusion, a positive eluate or a newly identified alloantibody in the plasma or serum along with features of haemolysis in the patient. Routinely, it is expected that with the transfusion of one unit of packed red cells in a patient of average height and weight, the haemoglobin level and hematocrit increase by 1 g/dL and 3% respectively. However, in a patient with DHTR, an inadequate rise of post-transfusion haemoglobin (<1 g/dL) or rapid fall in haemoglobin back to pre-transfusion levels is observed. Kidd antibodies are particularly known to cause DHTR, maybe alone or in unison with other antibodies. Detection of these alloantibodies is consequential in providing good transfusion support to these patients. These events may be difficult to detect as they may present as varied clinical features or immunological nuisances. In this case series, we have presented three cases of DHTR with special emphasis on their clinical presentations, immunohaematological evaluations, laboratory parameters and the role of proper transfusion support in these patients to avoid further complications. (Copyright © 2022 Société française de transfusion sanguine (SFTS). Published by Elsevier Masson SAS. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Alloimmunization; Anamnestic response; Anti-Jk(a) antibodies; Delayed haemolytic transfusion reaction; Kidd blood group antigen system |
| المشرفين على المادة: | 0 (Hemoglobins) 0 (Isoantibodies) |
| تواريخ الأحداث: | Date Created: 20220315 Date Completed: 20220823 Latest Revision: 20220823 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1016/j.tracli.2022.03.001 |
| PMID: | 35288280 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1953-8022 |
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| DOI: | 10.1016/j.tracli.2022.03.001 |