دورية أكاديمية

Could the perioperative use of opioids influence cancer outcomes after surgery? A scoping review protocol.

التفاصيل البيبلوغرافية
العنوان: Could the perioperative use of opioids influence cancer outcomes after surgery? A scoping review protocol.
المؤلفون: Cascella M; Division of Anesthesia and Pain Medicine, Istituto Nazionale Tumori, IRCCS Fondazione G. Pascale, Napoli, Italy m.cascella@istitutotumori.na.it., Cuomo A; Division of Anesthesia and Pain Medicine, Istituto Nazionale Tumori, IRCCS Fondazione G. Pascale, Napoli, Italy., Bifulco F; Division of Anesthesia and Pain Medicine, Istituto Nazionale Tumori, IRCCS Fondazione G. Pascale, Napoli, Italy., Perri F; Department of Head/Neck and Sarcoma Oncology, INT IRCCS G Pascale, Napoli, Italy., Carbone F; Dipartimento di Sanità Pubblica, Unversità di Napoli Federico II, Napoli, Italy., Aprea M; Division of Anesthesia, Roma, Italy., Forte CA; Division of Anesthesia and Pain Medicine, Istituto Nazionale Tumori, IRCCS Fondazione G. Pascale, Napoli, Italy., Fiore M; Università degli Studi della Campania Luigi Vanvitelli, Napoli, Italy.
المصدر: BMJ open [BMJ Open] 2022 Mar 15; Vol. 12 (3), pp. e054520. Date of Electronic Publication: 2022 Mar 15.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [London] : BMJ Publishing Group Ltd, 2011-
مواضيع طبية MeSH: Neoplasms*/surgery , Opioid-Related Disorders*, Analgesics, Opioid/adverse effects ; Humans ; Research Design ; Retrospective Studies ; Review Literature as Topic ; Systematic Reviews as Topic
مستخلص: Background: During and after general anaesthesia, opioids are commonly used for pain treatment. Since preclinical studies underlined the potential immunosuppressive activity of these drugs, it was postulated that their perioperative administration could influence cancer outcomes after surgery. Nevertheless, clinical data have been extrapolated mainly from retrospective analyses. Consequently, the precise link between perioperative opioid use and cancer recurrence/metastasis or cancer-related mortality/morbidity is still an unsolved issue.
Methods and Analysis: This scoping review is planned to follow the Joanna Briggs Institute recommendations. The authors will conduct a literature review through the PRISMA statement using PubMed and EMBASE databases; the Grey literature will be explored using Google Scholar and Conference Proceedings Citation Index (via Web of Science). The search strategy will be limited to articles published in the English language and to human studies. The database searches are planned from the inception to January 2022. Two reviewers will independently screen titles and abstracts, followed by a full-text screening of potentially relevant articles with standardised data extraction. Any disagreement for the inclusion between the two reviewers will be discussed with a third reviewer.
Ethics and Dissemination: The review aims to map the available literature, focusing on a possible association between perioperative opioid use and cancer outcomes in patients undergoing surgery. The proposed approach will be useful to identify and analyse the knowledge gap in the field and serve as a prerequisite for future research.
Scoping Review Registration: Open Science Framework https://osf.io/vfhw6/ DOI 10.17605/OSF.IO/VFHW6.
Competing Interests: Competing interests: None declared.
(© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
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فهرسة مساهمة: Keywords: Cancer Outcomes; Cancer Surgery; Opioid-free Anaesthesia; Opioids; Postoperative Analgesia
المشرفين على المادة: 0 (Analgesics, Opioid)
تواريخ الأحداث: Date Created: 20220316 Date Completed: 20220405 Latest Revision: 20220523
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC8928327
DOI: 10.1136/bmjopen-2021-054520
PMID: 35292495
قاعدة البيانات: MEDLINE
الوصف
تدمد:2044-6055
DOI:10.1136/bmjopen-2021-054520