دورية أكاديمية
What is the role of heat shock protein in abdominal organ transplantation?
| العنوان: | What is the role of heat shock protein in abdominal organ transplantation? |
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| المؤلفون: | Calil IL; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., Tustumi F; Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil., Sousa JHB; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., Tomazini BM; Hospital Sírio-Libanês, São Paulo, SP, Brazil., Cruz RJ Jr; School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Saliba GN; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., Pécora RAA; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., D'Albuquerque LAC; Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil. |
| المصدر: | Einstein (Sao Paulo, Brazil) [Einstein (Sao Paulo)] 2022 Mar 11; Vol. 20, pp. eRB6181. Date of Electronic Publication: 2022 Mar 11 (Print Publication: 2022). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Instituto de Ensino e Pesquisa Albert Einstein Country of Publication: Brazil NLM ID: 101281800 Publication Model: eCollection Cited Medium: Internet ISSN: 2317-6385 (Electronic) Linking ISSN: 16794508 NLM ISO Abbreviation: Einstein (Sao Paulo) Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: São Paulo, SP : Instituto de Ensino e Pesquisa Albert Einstein |
| مواضيع طبية MeSH: | Organ Transplantation* , Reperfusion Injury*, Heat-Shock Proteins/metabolism ; Humans ; Ischemia |
| مستخلص: | Ischemia-reperfusion injury is a pathophysiological event occuring after abdominal organ transplantation, and has a significant influence on prognosis and survival of the graft. It is involved in delaying the primary function or non-functioning of the graft. The objective of this study was to provide information on heat shock protein mechanisms in ischemia-reperfusion injuries in abdominal organ transplantations, and to indicate the possible factors involved that may influence the graft outcome. Several classes of heat shock proteins are part of the ischemia and reperfusion process, both as inflammatory agonists and in protecting the process. Studies involving heat shock proteins enhance knowledge on ischemia-reperfusion injury mitigation processes and the mechanisms involved in the survival of abdominal grafts, and open space to support therapeutic future clinical studies, minimizing ischemia and reperfusion injuries in abdominal organ transplantations. Expression of heat shock proteins is associated with inflammatory manifestations and ischemia-reperfusion injuries in abdominal organ transplantations and may influence graft outcomes. |
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| المشرفين على المادة: | 0 (Heat-Shock Proteins) |
| تواريخ الأحداث: | Date Created: 20220316 Date Completed: 20220317 Latest Revision: 20220318 |
| رمز التحديث: | 20221213 |
| مُعرف محوري في PubMed: | PMC8909122 |
| DOI: | 10.31744/einstein_journal/2022RB6181 |
| PMID: | 35293529 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2317-6385 |
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| DOI: | 10.31744/einstein_journal/2022RB6181 |