دورية أكاديمية
أعرض في EDS

Comparison of Salivary Electrolytes Profile in Oral Potentially Malignant Disorders and Oral Squamous Cell Carcinoma.

التفاصيل البيبلوغرافية
العنوان: Comparison of Salivary Electrolytes Profile in Oral Potentially Malignant Disorders and Oral Squamous Cell Carcinoma.
المؤلفون: Saavedra JA; Department of Oral Pathology and Medicine, Faculty of Dentistry, University of Chile, Santiago, Chile.; Graduate Program in Dentistry, Federal University of Pelotas, Pelotas, RS, Brazil., Novo DR; Center of Chemical, Pharmaceutical and Food Sciences, Federal University of Pelotas. Capão do Leão, RS, Brazil., Mesko MF; Center of Chemical, Pharmaceutical and Food Sciences, Federal University of Pelotas. Capão do Leão, RS, Brazil., Uchoa Vasconcellos AC; Diagnostic Center for Oral Diseases, Federal University of Pelotas. Pelotas, RS, Brazil., Duarte Da Silva K; Centro Universitário Ritter dos Reis, UniRitter, Porto Alegre, Rio Grande do Sul, Brazil., Rojas Zuñiga G; Department of Oral Pathology and Medicine, Faculty of Dentistry, University of Chile, Santiago, Chile., Ramires RF; Centro de Oncologia de Precisión-Universidad Mayo, Brazil., Tarquinio SBC; Diagnostic Center for Oral Diseases, Federal University of Pelotas. Pelotas, RS, Brazil.
المصدر: Asian Pacific journal of cancer prevention : APJCP [Asian Pac J Cancer Prev] 2022 Mar 01; Vol. 23 (3), pp. 1031-1039. Date of Electronic Publication: 2022 Mar 01.
نوع المنشور: Journal Article; Systematic Review
اللغة: English
بيانات الدورية: Publisher: Asian Pacific Organization for Cancer Prevention Country of Publication: Thailand NLM ID: 101130625 Publication Model: Electronic Cited Medium: Internet ISSN: 2476-762X (Electronic) Linking ISSN: 15137368 NLM ISO Abbreviation: Asian Pac J Cancer Prev Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Bangkok : Asian Pacific Organization for Cancer Prevention,
مواضيع طبية MeSH: Carcinoma, Squamous Cell*/pathology , Head and Neck Neoplasms* , Mouth Neoplasms*/pathology, Electrolytes ; Humans ; Observational Studies as Topic ; Squamous Cell Carcinoma of Head and Neck
مستخلص: Objectives: to determine salivary electrolyte concentration of oral potentially malignant disorders (OPMD) and oral squamous cell carcinoma (OSCC) patients. A related systematic review was performed.
Methods: Observational study. Unstimulated saliva from 18 patients with OSCC, 18 with OPMD, and 18 without oral lesions was collected. A biochemical analysis was performed to evaluate the salivary concentrations of potassium (K), phosphorus (P), sodium (Na), calcium (Ca), magnesium (Mg), zinc (Zn), copper (Cu), and iron (Fe). Kruskal-Wallis test was performed, and p < 0.05 was interpreted as statistically significant. The literature search for the systematic review retrieved 9 studies that associated salivary electrolyte levels with presence and progression of OSCC.
Results: A highly significant increase was found in the salivary Mg levels in the OPMD group (5.41 µg/mL) in comparison with the OSCC (3.71µg/mL) and control group (3.51 µg/mL) (p = 0.041). No differences were observed in other salivary levels elements. The results of the systematic review revealed that one article indicated a decrease, and three papers reported an increase in salivary Na levels in patients with OPMD and OSCC. Two articles indicated a decrease in salivary K levels in OSCC, and the other two reported high Mg levels in OPMD and OSCC.
Conclusion: High salivary Mg levels can be a potential biomarker indicating the presence of OPMD, however, the evidence is still contradictory and more studies are required.
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فهرسة مساهمة: Keywords: Electrolytes; Precancerous Condition; Saliva; trace elements
المشرفين على المادة: 0 (Electrolytes)
تواريخ الأحداث: Date Created: 20220329 Date Completed: 20220330 Latest Revision: 20220811
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC9360961
DOI: 10.31557/APJCP.2022.23.3.1031
PMID: 35345377
قاعدة البيانات: MEDLINE
الوصف
تدمد:2476-762X
DOI:10.31557/APJCP.2022.23.3.1031