دورية أكاديمية
Long-term outcomes with the On-X bileaflet mitral valve: clinical events up to 17 years in 661 patients.
| العنوان: | Long-term outcomes with the On-X bileaflet mitral valve: clinical events up to 17 years in 661 patients. |
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| المؤلفون: | Reyes G; Cardiac Surgery Department, Hospital Universitario La Princesa, c/Diego de León 62; 28006, Madrid, Spain., Muñoz D; Cardiac Surgery Department, Hospital Universitario La Princesa, c/Diego de León 62; 28006, Madrid, Spain., Monguio E; Cardiac Surgery Department, Hospital Universitario La Princesa, c/Diego de León 62; 28006, Madrid, Spain., Berastegui E; Cardiac Surgery Department, Hospital Universitario Germans Trias i Pujol, Crta.Canyet; 08916 Badalona; Barcelona, Spain., Camara ML; Cardiac Surgery Department, Hospital Universitario Germans Trias i Pujol, Crta.Canyet; 08916 Badalona; Barcelona, Spain., de Antonio N; Cardiac Surgery Department, Hospital Universitario La Princesa, c/Diego de León 62; 28006, Madrid, Spain., Julia I; Cardiac Surgery Department, Hospital Universitario Germans Trias i Pujol, Crta.Canyet; 08916 Badalona; Barcelona, Spain., Aguirre MF; Cardiac Surgery Department, Hospital Universitario La Princesa, c/Diego de León 62; 28006, Madrid, Spain., Fernandez C; Cardiac Surgery Department, Hospital Universitario Germans Trias i Pujol, Crta.Canyet; 08916 Badalona; Barcelona, Spain., Badia S; Cardiac Surgery Department, Hospital Universitario Germans Trias i Pujol, Crta.Canyet; 08916 Badalona; Barcelona, Spain., Muñoz-Guijosa C; Cardiac Surgery Department, Hospital Universitario Germans Trias i Pujol, Crta.Canyet; 08916 Badalona; Barcelona, Spain. |
| المصدر: | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery [Eur J Cardiothorac Surg] 2022 Oct 04; Vol. 62 (5). |
| نوع المنشور: | Observational Study; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Oxford University Press Country of Publication: Germany NLM ID: 8804069 Publication Model: Print Cited Medium: Internet ISSN: 1873-734X (Electronic) Linking ISSN: 10107940 NLM ISO Abbreviation: Eur J Cardiothorac Surg Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2012-: Oxford, England : Oxford University Press Original Publication: [Berlin] : Springer International ; [Secaucus, NJ, USA : Springer-Verlag New York Inc., distributor, c1987- |
| مواضيع طبية MeSH: | Heart Valve Prosthesis Implantation*/adverse effects , Mitral Valve Insufficiency*/surgery , Heart Valve Prosthesis*/adverse effects, Humans ; Female ; Middle Aged ; Aged ; Male ; Mitral Valve/surgery ; Treatment Outcome ; Reoperation/adverse effects ; Retrospective Studies ; Postoperative Complications/etiology |
| مستخلص: | Objectives: This study reports long-term clinical outcomes-up to 17 years-among patients undergoing mitral valve replacement with the On-X bileaflet mechanical valve. Prior data regarding long-term outcomes with the On-X mitral valve have been limited. Methods: This retrospective observational study included all patients who underwent mitral valve replacement with the On-X (Standard or Conform-X) valve at 2 major Spanish cardiac surgery centres between 2001 and 2018. The primary study end point was freedom from death. The secondary study end points included surgical mortality and freedom from any valve-related events. Data were obtained from an institutional database, medical records review, direct telephone interviews or the Spanish population registry. Statistical and Kaplan-Meier analyses were performed. Results: A total of 661 patients (mean age 63.1 ± 10.9 years, 63% female) were followed for a mean of 5.6 years (range, 0-17.4 years). Survival at 5, 10 and 15 years was 85%, 71% and 63%, respectively. Surgical mortality was 7.3% (48/661). The linearized rate of global mortality was 1.3% patient-year. Freedom from reoperation was 97%, 95% and 92% at 5, 10 and 15 years, respectively; freedom from anticoagulation-related events was 94%, 89% and 89%, respectively. Multivariable analysis showed that mortality increased with total length of stay, age, smoking history, severe pulmonary hypertension and a permanent pacemaker. Patients who received the On-X 25 -mm valve had decreased long-term survival relative to patients who received other On-X valve sizes, possibly due to underlying risk factors. Conclusions: Patients in this study showed good long-term survival and freedom from valve-related events. (© The Author(s) 2022. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Long-term outcomes; Mitral valve replacement; Mitral valve surgery; On-X mitral valve; Surgical outcomes; Survival |
| تواريخ الأحداث: | Date Created: 20220329 Date Completed: 20221101 Latest Revision: 20221116 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1093/ejcts/ezac157 |
| PMID: | 35348660 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1873-734X |
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| DOI: | 10.1093/ejcts/ezac157 |