دورية أكاديمية

High Asymptomatic Carriage With the Omicron Variant in South Africa.

التفاصيل البيبلوغرافية
العنوان: High Asymptomatic Carriage With the Omicron Variant in South Africa.
المؤلفون: Garrett N; Centre for the AIDS Programme of Research in South Africa, University of KwaZulu-Natal, Durban, South Africa., Tapley A; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.; University of Washington School of Medicine, Seattle, Washington, USA., Andriesen J; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Seocharan I; South African Medical Research Council, Cape Town, South Africa., Fisher LH; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Bunts L; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Espy N; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Wallis CL; Bio Analytical Research Corporation South Africa and Lancet Laboratories, Johannesburg, South Africa., Randhawa AK; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Miner MD; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Ketter N; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Yacovone M; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA., Goga A; South African Medical Research Council, Cape Town, South Africa.; University of Pretoria, Pretoria, South Africaand., Huang Y; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.; Department of Global Health, University of Washington, Seattle, Washington, USA., Hural J; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Kotze P; Qhakaza Mbokodo Research Clinic, Ladysmith, South Africa., Bekker LG; Desmond Tutu HIV Centre, University of Cape Town, Cape Town, South Africa., Gray GE; South African Medical Research Council, Cape Town, South Africa., Corey L; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
مؤلفون مشاركون: Ubuntu Study Team
المصدر: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2022 Aug 24; Vol. 75 (1), pp. e289-e292.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9203213 Publication Model: Print Cited Medium: Internet ISSN: 1537-6591 (Electronic) Linking ISSN: 10584838 NLM ISO Abbreviation: Clin Infect Dis Subsets: MEDLINE
أسماء مطبوعة: Publication: Jan. 2011- : Oxford : Oxford University Press
Original Publication: Chicago, IL : The University of Chicago Press, c1992-
مواضيع طبية MeSH: COVID-19* , SARS-CoV-2*, Humans ; Polymerase Chain Reaction ; South Africa/epidemiology
مستخلص: We report a 23% asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) Omicron carriage rate in participants being enrolled into a clinical trial in South Africa, 15-fold higher than in trials before Omicron. We also found lower CD4 + T-cell counts in persons with human immunodeficiency virus (HIV) strongly correlated with increased odds of being SARS-CoV-2 polymerase chain reaction (PCR) positive.
(© The Author(s) 2022. Published by Oxford University Press for the Infectious Diseases Society of America.)
معلومات مُعتمدة: UM1 AI069432 United States AI NIAID NIH HHS; T32 AI007044 United States AI NIAID NIH HHS; UM1 AI069469 United States AI NIAID NIH HHS; UM1 AI068618 United States AI NIAID NIH HHS; U01 AI068636 United States AI NIAID NIH HHS; UM1 AI069463 United States AI NIAID NIH HHS; UM1 AI068614 United States AI NIAID NIH HHS; UM1 AI068635 United States AI NIAID NIH HHS; INV-030342 United States GATES Bill & Melinda Gates Foundation
فهرسة مساهمة: Investigator: K Ahmed; S Badal-Faesen; S Barnabas; W Brumskine; K Comline; A Diacon; T Dubula; K Gill; C Grobbelaar; C Innes; S Kassim; S Kotze; E Lazarus; J Lombaard; A Luabeya; RM Maboa; S Mahoney; D Mahkaza; M Malahleha; D Malan; K Mngadi; N Naicker; V Naicker; L Naidoo; M Nchabeleng; M Rassool; E Spooner; H Tempelman; N Mgodi; S Dadabhai; J Makhema; H Nuwagaba-Biribonwoha; T Samandari; PJ Elyanu; R Chilengi; Z Chirenje; J McElrath; M Cohen; J Kublin; P Gilbert; M Peda; E Andersen-Nissen; G Ferrari; M Villaran; A Takalani; M Gildea; M Nebergall; C Sopher; L Proulx-Burns; D Govender; L Sanders; J Hanke; K Baepanye; BL Roux; H Wilvich; S Sripathy; D Margineantu; V Brown; K Linton; H Howell; B Noronha; S Nikles; A Toledano; J May; J El-Khorazaty; K Naidoo; A Takalani; K Khuto; F Mayat; L Fairall; I Sanne
Keywords: Omicron variant; PWH; SARS-CoV-2; South Africa; asymptomatic carriage
SCR Organism: SARS-CoV-2 variants
تواريخ الأحداث: Date Created: 20220330 Date Completed: 20220829 Latest Revision: 20240827
رمز التحديث: 20240827
مُعرف محوري في PubMed: PMC9383623
DOI: 10.1093/cid/ciac237
PMID: 35353885
قاعدة البيانات: MEDLINE
الوصف
تدمد:1537-6591
DOI:10.1093/cid/ciac237