دورية أكاديمية
أعرض في EDS

Thiol redox switches regulate the oligomeric state of cyanobacterial Rre1, RpaA and RpaB response regulators.

التفاصيل البيبلوغرافية
العنوان: Thiol redox switches regulate the oligomeric state of cyanobacterial Rre1, RpaA and RpaB response regulators.
المؤلفون: Ibrahim IM; Department of Biochemistry and Center for Plant Biology, Purdue University, West Lafayette, IN, USA., Rowden SJL; Department of Biochemistry, University of Cambridge, UK., Cramer WA; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA., Howe CJ; Department of Biochemistry, University of Cambridge, UK., Puthiyaveetil S; Department of Biochemistry and Center for Plant Biology, Purdue University, West Lafayette, IN, USA.
المصدر: FEBS letters [FEBS Lett] 2022 Jun; Vol. 596 (12), pp. 1533-1543. Date of Electronic Publication: 2022 Apr 11.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
اللغة: English
بيانات الدورية: Publisher: John Wiley & Sons Ltd Country of Publication: England NLM ID: 0155157 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3468 (Electronic) Linking ISSN: 00145793 NLM ISO Abbreviation: FEBS Lett Subsets: MEDLINE
أسماء مطبوعة: Publication: Jan. 2016- : West Sussex : John Wiley & Sons Ltd.
Original Publication: Amsterdam, North-Holland on behalf of the Federation of European Biochemical Societies.
مواضيع طبية MeSH: Synechocystis*/genetics , Synechocystis*/metabolism, Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Cyanobacteria/genetics ; Cyanobacteria/metabolism ; Gene Expression Regulation, Bacterial/genetics ; Oxidation-Reduction ; Sulfhydryl Compounds ; Thioredoxins/genetics ; Thioredoxins/metabolism
مستخلص: Cyanobacteria employ two-component sensor-response regulator systems to monitor and respond to environmental challenges. The response regulators RpaA, RpaB, Rre1 and RppA are integral to circadian clock function and abiotic stress acclimation in cyanobacteria. RpaA, RpaB and Rre1 are known to interact with ferredoxin or thioredoxin, raising the possibility of their thiol regulation. Here, we report that Synechocystis sp. PCC 6803 Rre1, RpaA and RpaB exist as higher-order oligomers under oxidising conditions and that reduced thioredoxin A converts them to monomers. We further show that these response regulators contain redox-responsive cysteine residues with an E m7 around -300 mV. These findings suggest a direct thiol modulation of the activity of these response regulators, independent of their cognate sensor kinases.
(© 2022 The Authors. FEBS Letters published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies.)
References: Commun Biol. 2020 Jan 8;3(1):13. (PMID: 31925322)
Plant Cell Physiol. 2022 Feb 15;63(2):176-188. (PMID: 34750635)
Proc Biol Sci. 2009 Jun 22;276(1665):2133-45. (PMID: 19324807)
Microbiol Mol Biol Rev. 2006 Jun;70(2):472-509. (PMID: 16760311)
Science. 2011 Jan 14;331(6014):220-3. (PMID: 21233390)
Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):2198-203. (PMID: 25653337)
J Biol Chem. 1991 Mar 5;266(7):4056-66. (PMID: 1999401)
Annu Rev Genet. 2007;41:121-45. (PMID: 18076326)
Biochemistry. 1989 Jun 13;28(12):5282-7. (PMID: 2669972)
DNA Res. 2007 Oct 31;14(5):207-16. (PMID: 18000013)
Front Plant Sci. 2016 Feb 12;7:137. (PMID: 26904089)
Antioxid Redox Signal. 2010 Jan;12(1):53-91. (PMID: 19634988)
Mol Syst Biol. 2008;4:165. (PMID: 18277381)
FEMS Microbiol Lett. 2003 Sep 12;226(1):135-44. (PMID: 13129619)
Mol Microbiol. 2002 Jan;43(1):247-56. (PMID: 11849552)
Mol Plant. 2009 Mar;2(2):270-83. (PMID: 19825613)
PLoS One. 2015 Mar 16;10(3):e0119107. (PMID: 25774906)
Proteomics. 2007 Nov;7(21):3953-63. (PMID: 17922517)
Proc Natl Acad Sci U S A. 2008 Jul 22;105(29):10061-6. (PMID: 18632566)
J Biol Chem. 2015 Aug 7;290(32):19540. (PMID: 26254269)
J Bacteriol. 2000 Aug;182(15):4268-77. (PMID: 10894737)
FEMS Microbiol Lett. 2002 Aug 27;214(1):25-30. (PMID: 12204368)
Adv Genet. 2011;74:13-53. (PMID: 21924974)
Biochim Biophys Acta. 2011 Feb;1814(2):366-74. (PMID: 20869472)
Science. 1998 Sep 4;281(5382):1519-23. (PMID: 9727980)
Fold Des. 1998;3(3):161-71. (PMID: 9562546)
Mol Microbiol. 2017 Apr;104(2):260-277. (PMID: 28106321)
J Mol Biol. 1993 Oct 20;233(4):559-66. (PMID: 8411164)
Genome Biol Evol. 2010;2:888-96. (PMID: 21071627)
FEMS Microbiol Lett. 1999 Dec 15;181(2):253-60. (PMID: 10585546)
Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):12109-14. (PMID: 16882723)
J Biol Chem. 2004 Dec 17;279(51):53078-86. (PMID: 15471853)
J Mol Biol. 2005 May 27;349(1):11-26. (PMID: 15876365)
Philos Trans R Soc Lond B Biol Sci. 2013 Jun 10;368(1622):20120260. (PMID: 23754813)
Cell. 2000 Apr 14;101(2):223-33. (PMID: 10786837)
J Exp Bot. 2020 Mar 25;71(6):2018-2027. (PMID: 31863668)
Adv Enzymol Relat Areas Mol Biol. 1990;63:69-172. (PMID: 2407068)
Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):E580-E589. (PMID: 28074036)
FEBS Lett. 2021 May;595(10):1480-1492. (PMID: 33728661)
معلومات مُعتمدة: BB/L014130/1 United Kingdom BB_ Biotechnology and Biological Sciences Research Council; BB/T010525/1 United Kingdom BB_ Biotechnology and Biological Sciences Research Council
فهرسة مساهمة: Keywords: Hik2; RpaA; RpaB; Rre1; TrxA; thiol regulation
المشرفين على المادة: 0 (Bacterial Proteins)
0 (Sulfhydryl Compounds)
52500-60-4 (Thioredoxins)
تواريخ الأحداث: Date Created: 20220330 Date Completed: 20220629 Latest Revision: 20221025
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC9321951
DOI: 10.1002/1873-3468.14340
PMID: 35353903
قاعدة البيانات: MEDLINE
الوصف
تدمد:1873-3468
DOI:10.1002/1873-3468.14340