دورية أكاديمية
أعرض في EDS

Ulcerative Colitis-Induced Colorectal Carcinoma: A Deleterious Concatenation.

التفاصيل البيبلوغرافية
العنوان: Ulcerative Colitis-Induced Colorectal Carcinoma: A Deleterious Concatenation.
المؤلفون: Rivera AP; Research, Universidad Americana (UAM) Facultad de Medicina, Managua, NIC., Flores Monar GV; Research, Universidad Central del Ecuador, Quito, ECU., Islam H; Research, Faisalabad Medical University, Faisalabad, PAK., Puttagunta SM; Research, Dr. P.S.I. (Pinnamaneni Siddhartha Institute) Medical College, Chinoutpalli, IND., Islam R; Research, Faisalabad Medical University, Faisalabad, PAK., Kundu S; Research, R G Kar Medical College, Kolkata, IND., Jha SB; Research, Jinan University School of Medicine, Guangzhou, CHN., Sange I; Research, K. J. Somaiya Medical College, Hospital and Research Center, Mumbai, IND.
المصدر: Cureus [Cureus] 2022 Feb 26; Vol. 14 (2), pp. e22636. Date of Electronic Publication: 2022 Feb 26 (Print Publication: 2022).
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Cureus, Inc Country of Publication: United States NLM ID: 101596737 Publication Model: eCollection Cited Medium: Print ISSN: 2168-8184 (Print) Linking ISSN: 21688184 NLM ISO Abbreviation: Cureus Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Palo Alto, CA : Cureus, Inc.
مستخلص: Inflammatory bowel disease (IBD) is a chronic inflammatory gastrointestinal ailment that encompasses Crohn's disease (CD) and ulcerative colitis (UC). UC is an idiopathic, chronic inflammatory condition of the colonic mucosa that begins in the rectum and progresses proximally in a continuous way over a portion of the entire colon. Chronic inflammation is linked to cancer, and IBD-related chronic colonic inflammation raises the risk of colorectal cancer. Chronic inflammation has been linked to cancer, and chronic colonic inflammation caused by IBD increases the risk of colorectal cancer (CRC). When CRC arises in people with IBD, unlike sporadic CRC, the lesions are difficult to identify due to mucosal alterations produced by inflammation. The total prevalence of IBD-associated CRC is increasing due to the rapidly increasing frequency of IBD. Screening and surveillance colonoscopy in IBD patients is considered to allow for the early diagnosis of dysplasia and cancer, improving the prognosis of IBD-related CRC by giving patients proactive therapy. This article has reviewed literature pertaining to the mechanisms related to CRC development in UC and its clinical and therapeutic implications.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2022, Rivera et al.)
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فهرسة مساهمة: Keywords: colon cancer; colon cancer screening; colon cancer surveillance; colonoscopy; colorectal carcinoma; ibd; ibd associated cancer; inflammatory bowel disease; uc; ulcerative colitis
تواريخ الأحداث: Date Created: 20220404 Latest Revision: 20220405
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC8959421
DOI: 10.7759/cureus.22636
PMID: 35371788
قاعدة البيانات: MEDLINE
الوصف
تدمد:2168-8184
DOI:10.7759/cureus.22636