Contribution of the anaerobic blood culture vial for the recovery of Candida glabrata: A retrospective multicentric study.

التفاصيل البيبلوغرافية
العنوان:	Contribution of the anaerobic blood culture vial for the recovery of Candida glabrata: A retrospective multicentric study.
المؤلفون:	Farfour E; Service de biologie clinique, Hôpital Foch, 92150 Suresnes, France., Le Brun C; Service de microbiologie, CHU Bretonneau, 37000 Tours, France., Mizrahi A; Service de biologie, GH Paris Saint-Joseph, 75015 Paris, France., Bargain P; Service de biologie, Hôpital A. Mignot, 78150 Le Chesnay-Rocquencourt, France., Durieux MF; service de parasitologie-mycologie, CHU Limoges, 87000 Limoges, France., Boquel F; Unité de parasitologie-mycologie, Département de Prévention, diagnostic et traitement des infections. CHU Henri Mondor, APHP, 94000 Créteil, France., Corvec S; Service de Bactériologie et des contrôles microbiologiques des produits de santé, CHU de Nantes, 44000 Nantes, France., Jeddi F; Laboratoire de Parasitologie et Mycologie Médicale, CHU de Nantes, 44000 Nantes, France., Muggeo A; UMR-S 1250 P3Cell, Inserm, Universitéde Reims-Champagne-Ardenne, SFR CAP-Santé, 51097 Reims, France; Laboratoire de microbiologie CHU Reims, Hôpital Robert Debré, 51100 Reims, France.; Laboratoire de Bactériologie-Virologie-Hygiène Hospitalière-Parasitologie-Mycologie, 51100, Reims, France., Huguenin A; Laboratoire de Bactériologie-Virologie-Hygiène Hospitalière-Parasitologie-Mycologie, 51100, Reims, France.; EA 7510, ESCAPE, Laboratoire de Parasitologie-Mycologie, Université de Reims Champagne-Ardenne, 51 rue Cognacq Jay, 51092 Reims CEDEX, France., Barraud O; Service de bactériologie- virologie-hygiène, CHU Limoges, 87000 Limoges, France., Amara M; Service de biologie, Hôpital A. Mignot, 78150 Le Chesnay-Rocquencourt, France., Fihman V; Bacteriology and Infection control Unit, Department of Prevention, Diagnosis, and Treatment of Infections, Henri-Mondor University Hospital, AP-HP, 94000 Créteil, France.; EA 7380 Dynamyc, EnvA, UPEC, Paris-Est University, 94000 Créteil, France., Bailly E; Service de Parasitologie-mycologie, CHU Bretonneau, 37000 Tours, France., Botterel F; Unité de parasitologie-mycologie, Département de Prévention, diagnostic et traitement des infections. CHU Henri Mondor, APHP, 94000 Créteil, France., Guillard T; UMR-S 1250 P3Cell, Inserm, Universitéde Reims-Champagne-Ardenne, SFR CAP-Santé, 51097 Reims, France; Laboratoire de microbiologie CHU Reims, Hôpital Robert Debré, 51100 Reims, France.; Laboratoire de Bactériologie-Virologie-Hygiène Hospitalière-Parasitologie-Mycologie, 51100, Reims, France., Vasse M; Service de biologie clinique, Hôpital Foch, 92150 Suresnes, France.
مؤلفون مشاركون:	GMC study group
المصدر:	Medical mycology [Med Mycol] 2022 Apr 29; Vol. 60 (4).
نوع المنشور:	Journal Article; Multicenter Study
اللغة:	English
بيانات الدورية:	Publisher: Oxford University Press Country of Publication: England NLM ID: 9815835 Publication Model: Print Cited Medium: Internet ISSN: 1460-2709 (Electronic) Linking ISSN: 13693786 NLM ISO Abbreviation: Med Mycol Subsets: MEDLINE
أسماء مطبوعة:	Publication: 2014- : Oxford : Oxford University Press Original Publication: Oxford : Blackwell Science, c1998-
مواضيع طبية MeSH:	Candidemia/diagnosis , Candidemia/veterinary, Anaerobiosis ; Animals ; Blood Culture/veterinary ; Candida ; Candida albicans ; Candida glabrata ; Humans ; Retrospective Studies
مستخلص:	Although Candida spp are aerobic microorganisms, some Candida strains, mainly Candida glabrata, can be recovered from anaerobic blood culture vials. We assessed the contribution of the anaerobic vials for the diagnosis of candidemia, especially for C. glabrata. We conducted a multicenter retrospective study including eight university or regional hospitals. A single episode of monomicrobial candidemia per patient was included from September 1st, 2016, to August 31st, 2019. The characteristics of all aerobic and anaerobic blood culture vials sampled within 2 h before and after the first positive blood culture vials were recorded (type of vials, result, and for positive vials time-to-positivity and Candida species). Overall, 509 episodes of candidemia were included. The main species were C. albicans (55.6%) followed by C. glabrata (17.1%), C. parapsilosis (4.9%), and C. tropicalis (4.5%). An anaerobic vial was positive in 76 (14.9%) of all episodes of which 56 (73.8%) were due to C. glabrata. The number of C. glabrata infections only positive in anaerobic vials was 1 (2.6%), 1 (11.1%), and 15 (37.5%) with the BACT/ALERT 3D the BACT/ALERT VIRTUO and the BACTEC FX instrument, respectively (P < 0.01). The initial positivity of an anaerobic vial was highly predictive of the isolation of C. glabrata with the BACTEC FX (sensitivity of 96.8%). C. glabrata time-to-positivity was shorter in anaerobic vial than aerobic vial with all instruments. Anaerobic blood culture vials improve the recovery of Candida spp mainly C. glabrata. This study could be completed by further analyses including mycological and pediatric vials. Lay Summary: Although Candida spp are aerobic microorganisms, C. glabrata is able to grow in anaerobic conditions. In blood culture, the time-to-positivity of C. glabrata is shorter in anaerobic than aerobic vials. Only the anaerobic vial was positive in up to 15 (37.5%) C. glabrata bloodstream infections. (© The Author(s) 2022. Published by Oxford University Press on behalf of The International Society for Human and Animal Mycology.)
فهرسة مساهمة:	Investigator: A Guillouzouic; LR d'Epenoux; P Bémer; ME Juvin; PL Woerther; F Foulet; NA Ammar; P Le Pape; I Villena; C Des Champs; L Mereghetti; G Desoubeaux; A Le Monnier; D Ajzenberg; B Maneglier Keywords: BACT/ALERT; Bactec; Candida; Virtuo; anaerobic blood culture; time-to-positivity
تواريخ الأحداث:	Date Created: 20220411 Date Completed: 20220502 Latest Revision: 20220502
رمز التحديث:	20240628
DOI:	10.1093/mmy/myac021
PMID:	35404411
قاعدة البيانات:	MEDLINE

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الوصف
تدمد:	1460-2709
DOI:	10.1093/mmy/myac021