دورية أكاديمية
Surgical management of pediatric intracranial cerebral cavernous malformations: a 10-year single-center experience.
| العنوان: | Surgical management of pediatric intracranial cerebral cavernous malformations: a 10-year single-center experience. |
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| المؤلفون: | Calloni T; Department of Medicine and Surgery, School of Medicine, University of Milan-Bicocca, Milan, Italy.; Neurosurgery Unit, Department of Neurosciences, IRCCS Bambino Gesù Children's Hospital, Rome, Italy., Carai A; Neurosurgery Unit, Department of Neurosciences, IRCCS Bambino Gesù Children's Hospital, Rome, Italy - andrea.carai@opbg.net., Lioi F; Division of Neurosurgery, Department of Neurology and Psychiatry, Sapienza University, Rome, Italy., Cavaliere M; Department of Medicine and Surgery, School of Medicine, University of Milan-Bicocca, Milan, Italy.; Neurosurgery Unit, Department of Neurosciences, IRCCS Bambino Gesù Children's Hospital, Rome, Italy., DE Benedictis A; Neurosurgery Unit, Department of Neurosciences, IRCCS Bambino Gesù Children's Hospital, Rome, Italy., Rossi S; Pathology Unit, Department of Laboratories, IRCCS Bambino Gesù Children's Hospital, Rome, Italy., Randi F; Neurosurgery Unit, Department of Neurosciences, IRCCS Bambino Gesù Children's Hospital, Rome, Italy., Rossi Espagnet MC; Neuroradiology Unit, Imaging Department, IRCCS Bambino Gesù Children's Hospital, Rome, Italy., Trivisano M; Neurology Unit, Department of Neurosciences, IRCCS Bambino Gesù Children's Hospital, Rome, Italy., Cesario C; Translational Cytogenomics Research Unit, IRCCS Bambino Gesù Children's Hospital, Rome, Italy., Pisaneschi E; Translational Cytogenomics Research Unit, IRCCS Bambino Gesù Children's Hospital, Rome, Italy., Marasi A; Neurosurgery Unit, Department of Neurosciences, IRCCS Bambino Gesù Children's Hospital, Rome, Italy., Savioli A; Department of Anesthesia and Critical Care (ARCO), IRCCS Bambino Gesù Children's Hospital, Rome, Italy., Giussani CG; Department of Medicine and Surgery, School of Medicine, University of Milan-Bicocca, Milan, Italy.; Neurosurgery Unit, Department of Neurosciences, San Gerardo Hospital, Monza, Italy., Marras CE; Neurosurgery Unit, Department of Neurosciences, IRCCS Bambino Gesù Children's Hospital, Rome, Italy. |
| المصدر: | Journal of neurosurgical sciences [J Neurosurg Sci] 2024 Jun; Vol. 68 (3), pp. 278-286. Date of Electronic Publication: 2022 Apr 13. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Minerva Medica Country of Publication: Italy NLM ID: 0432557 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1827-1855 (Electronic) Linking ISSN: 03905616 NLM ISO Abbreviation: J Neurosurg Sci Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Milano : Minerva Medica Original Publication: Turin, Minerva medica. |
| مواضيع طبية MeSH: | Hemangioma, Cavernous, Central Nervous System*/surgery , Neurosurgical Procedures*/methods, Humans ; Child ; Female ; Male ; Child, Preschool ; Adolescent ; Infant ; Treatment Outcome |
| مستخلص: | Background: Cerebral cavernous malformations (CCMs) are low-flow vascular malformations made up of dilated vascular spaces without intervening parenchyma that can occur throughout the central nervous system. CCMs can occur sporadically or in familial forms. Presentation is diverse, ranging from incidental discovery of asymptomatic CCMs to drug-resistant epilepsy and hemorrhages. Methods: We describe the surgical management of CCMs in pediatric patients at Bambino Gesù Children's Hospital in Rome over the last 10 years. The cases have been stratified based on the clinical presentation and the relevant literature is discussed accordingly. Results: We discuss the rationale and technique used in these cases based on their presentation, as well as the generally positive outcomes we achieved with early surgical management, use of intraoperative ultrasound (ioUS) and intraoperative neuromonitoring. Conclusions: Surgical management of pediatric CCMs is a safe and effective strategy, low rates of postoperative morbidity and partial resection were observed. |
| تواريخ الأحداث: | Date Created: 20220413 Date Completed: 20240604 Latest Revision: 20240604 |
| رمز التحديث: | 20240604 |
| DOI: | 10.23736/S0390-5616.22.05574-6 |
| PMID: | 35416451 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1827-1855 |
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| DOI: | 10.23736/S0390-5616.22.05574-6 |