دورية أكاديمية
Anti-viral activity of thiazole derivatives: an updated patent review.
| العنوان: | Anti-viral activity of thiazole derivatives: an updated patent review. |
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| المؤلفون: | Farghaly TA; Department of Chemistry, Faculty of Science, Cairo University, Giza, Egypt., Alsaedi AMR; Department of Chemistry, College of Science, Taif University, Taif, Saudi Arabia., Alenazi NA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia., Harras MF; Department of Pharmaceutical Medicinal Chemistry, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt. |
| المصدر: | Expert opinion on therapeutic patents [Expert Opin Ther Pat] 2022 Jul; Vol. 32 (7), pp. 791-815. Date of Electronic Publication: 2022 Apr 27. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Informa Healthcare Country of Publication: England NLM ID: 9516419 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-7674 (Electronic) Linking ISSN: 13543776 NLM ISO Abbreviation: Expert Opin Ther Pat Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: London : Informa Healthcare Original Publication: London : Ashley Pub. Ltd., c1994- |
| مواضيع طبية MeSH: | Thiazoles*/chemistry , Thiazoles*/pharmacology , Thiazoles*/therapeutic use , Virus Diseases*/drug therapy, Antiviral Agents/pharmacology ; Antiviral Agents/therapeutic use ; Humans ; Patents as Topic |
| مستخلص: | Introduction: Several viral infections cause life-threatening consequences in humans, making them the most serious public health concerns. Despite the fact that several antiviral medicines are available on the market, there is no full treatment for many important viral infections. To date, antiviral medicines have significantly reduced the spread of epidemics, but their continued use has resulted in the creation of drug-resistant variants throughout time. As a result, the development of new, safe, and efficient antiviral drugs is critical. Areas Covered: This review covered reports in the patent literature in the period 2014 to the first quarter of 2021 on the antiviral activities of thiazole derivatives. These molecules were reported to inhibit a wide range of viruses including influenza viruses, coronaviruses, herpes viruses, hepatitis B and C, bovine viral diarrhea virus, chikungunya virus and human immunodeficiency viruses. Expert Opinion: The most bioactive molecules can be used as lead structures for the development of new thiazole compounds with potent and selective antiviral activity. In addition, more efforts are needed to better understand the host-virus interactions for the discovery and development of new therapeutic agents and creative treatment strategies that are supposed to improve rates of clinical cure of the serious viruses. |
| فهرسة مساهمة: | Keywords: anti-HBV; anti-HCV; anti-viral; biological activity; thiazoles |
| المشرفين على المادة: | 0 (Antiviral Agents) 0 (Thiazoles) |
| تواريخ الأحداث: | Date Created: 20220415 Date Completed: 20220620 Latest Revision: 20220620 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1080/13543776.2022.2067477 |
| PMID: | 35427454 |
| قاعدة البيانات: | MEDLINE |
PDF full text from Publisher | تدمد: | 1744-7674 |
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| DOI: | 10.1080/13543776.2022.2067477 |