دورية أكاديمية
High Impact of Pediatric Inflammatory Bowel Disease on Caregivers' Work Productivity and Daily Activities: An International Prospective Study.
| العنوان: | High Impact of Pediatric Inflammatory Bowel Disease on Caregivers' Work Productivity and Daily Activities: An International Prospective Study. |
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| المؤلفون: | Klomberg RCW; Department of Pediatric Gastroenterology, Erasmus Medical Center, Sophia Children's Hospital, Rotterdam, The Netherlands. Electronic address: r.klomberg@erasmusmc.nl., Aardoom MA; Department of Pediatric Gastroenterology, Erasmus Medical Center, Sophia Children's Hospital, Rotterdam, The Netherlands., Kemos P; Pediatric Gastroenterology, Center for Immunobiology, Blizard Institute, Barts and the London School of Medicine, Queen Mary University of London, London, UK., Rizopoulos D; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands., Ruemmele FM; Department of Pediatric Gastroenterology, University of Paris Descartes, Sorbonne Paris City, APHP, Necker Hospital for Sick Children, Paris, France., Croft NM; Pediatric Gastroenterology, Center for Immunobiology, Blizard Institute, Barts and the London School of Medicine, Queen Mary University of London, London, UK., de Ridder L; Department of Pediatric Gastroenterology, Erasmus Medical Center, Sophia Children's Hospital, Rotterdam, The Netherlands., Neyt M; Medical Evaluation and Technology Assessment, Merendree, Belgium. |
| مؤلفون مشاركون: | PIBD-SET Quality consortium |
| المصدر: | The Journal of pediatrics [J Pediatr] 2022 Jul; Vol. 246, pp. 95-102.e4. Date of Electronic Publication: 2022 Apr 14. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Mosby Country of Publication: United States NLM ID: 0375410 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6833 (Electronic) Linking ISSN: 00223476 NLM ISO Abbreviation: J Pediatr Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: St. Louis, MO : Mosby |
| مواضيع طبية MeSH: | Caregivers* , Inflammatory Bowel Diseases*/therapy, Child ; Chronic Disease ; Efficiency ; Humans ; Prospective Studies ; Quality of Life ; Surveys and Questionnaires |
| مستخلص: | Objectives: To evaluate the longitudinal evolution of work productivity loss and activity impairment in caregivers of children with inflammatory bowel disease (IBD). We also evaluated the associations between these impairments, IBD-related factors, and caregivers' health-related quality of life (HRQOL) and estimated the indirect costs related to work absenteeism. Study Design: Since January 2017, children with newly diagnosed IBD were enrolled prospectively in the Pediatric Inflammatory Bowel Disease Network for Safety, Efficacy, Treatment and Quality improvement of care study. The impact of pediatric-onset IBD on caregivers' socioeconomic functioning (work and daily activities) and HRQOL was assessed using the Work Productivity and Activity Impairment for caregivers questionnaire and the European Quality of Life Five Dimension Five Level questionnaire, at diagnosis and 3 and 12 months of age. Generalized estimating equation models were applied to evaluate outcomes longitudinally, adjusted for IBD type, disease activity, and child's age at diagnosis. Results: Up to July 2021, 491 children with IBD were eligible for analysis of caregivers' Work Productivity and Activity Impairment questionnaire. At diagnosis, the mean caregivers' employment rate was 78.4%; the adjusted mean work productivity loss was 44.6% (95% CI, 40.2%-49.0%), and the adjusted mean activity impairment was 34.3% (95% CI, 30.8%-37.7%). Work productivity loss and activity impairment significantly decreased over time and were associated with disease activity, but not with IBD type or child's age. Caregivers' HRQOL was associated with both impairments. Costs related to work absenteeism were at least €6272 ($7276) per patient during the first year after diagnosis. Conclusions: Caregivers of children with IBD experience significant impairments in work and daily activities, especially at diagnosis. The impact decreases thereafter and is associated with disease activity and caregivers' HRQOL. Work absenteeism results in high indirect costs. (Crown Copyright © 2022. Published by Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Investigator: D Turner; G Focht; J Samsom; G Veereman; S Koletzko; A Brückner; A Levine; R Russell; A Griffiths; M Aloi; T Walters; M Walker Keywords: Crohn's disease; children; employment; health economics; parents; socioeconomic; ulcerative colitis |
| تواريخ الأحداث: | Date Created: 20220416 Date Completed: 20220628 Latest Revision: 20220726 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1016/j.jpeds.2022.04.014 |
| PMID: | 35429506 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1097-6833 |
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| DOI: | 10.1016/j.jpeds.2022.04.014 |