دورية أكاديمية
Research Advances on Matrine.
| العنوان: | Research Advances on Matrine. |
|---|---|
| المؤلفون: | Sun XY; College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China., Jia LY; College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China., Rong Z; College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China., Zhou X; Xi'an Key Laboratory of Basic and Translation of Cardiovascular Metabolic Disease, Shaanxi Key Laboratory of Ischemic Cardiovascular Disease, Institute of Basic and Translational Medicine, Xi'an Medical University, Xi'an, China., Cao LQ; Xi'an Key Laboratory of Basic and Translation of Cardiovascular Metabolic Disease, Shaanxi Key Laboratory of Ischemic Cardiovascular Disease, Institute of Basic and Translational Medicine, Xi'an Medical University, Xi'an, China., Li AH; Shaanxi Key Laboratory of Chinese Herb and Natural Drug Development, Medicine Research Institute, Shaanxi Pharmaceutical Holding Group Co., LTD, Xi'an, China., Guo M; College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China., Jin J; College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China., Wang YD; College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China., Huang L; College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China., Li YH; College of Life Sciences, Northwest University, Xi'an, China., He ZJ; College of Life Sciences, Northwest University, Xi'an, China., Li L; Xi'an Key Laboratory of Basic and Translation of Cardiovascular Metabolic Disease, Shaanxi Key Laboratory of Ischemic Cardiovascular Disease, Institute of Basic and Translational Medicine, Xi'an Medical University, Xi'an, China., Ma RK; Xi'an Key Laboratory of Basic and Translation of Cardiovascular Metabolic Disease, Shaanxi Key Laboratory of Ischemic Cardiovascular Disease, Institute of Basic and Translational Medicine, Xi'an Medical University, Xi'an, China., Lv YF; Xi'an Key Laboratory of Basic and Translation of Cardiovascular Metabolic Disease, Shaanxi Key Laboratory of Ischemic Cardiovascular Disease, Institute of Basic and Translational Medicine, Xi'an Medical University, Xi'an, China., Shao KK; Xi'an Key Laboratory of Basic and Translation of Cardiovascular Metabolic Disease, Shaanxi Key Laboratory of Ischemic Cardiovascular Disease, Institute of Basic and Translational Medicine, Xi'an Medical University, Xi'an, China., Zhang J; College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China., Cao HL; College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China.; Xi'an Key Laboratory of Basic and Translation of Cardiovascular Metabolic Disease, Shaanxi Key Laboratory of Ischemic Cardiovascular Disease, Institute of Basic and Translational Medicine, Xi'an Medical University, Xi'an, China.; Shaanxi Key Laboratory of Chinese Herb and Natural Drug Development, Medicine Research Institute, Shaanxi Pharmaceutical Holding Group Co., LTD, Xi'an, China.; College of Life Sciences, Northwest University, Xi'an, China. |
| المصدر: | Frontiers in chemistry [Front Chem] 2022 Apr 01; Vol. 10, pp. 867318. Date of Electronic Publication: 2022 Apr 01 (Print Publication: 2022). |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101627988 Publication Model: eCollection Cited Medium: Print ISSN: 2296-2646 (Print) Linking ISSN: 22962646 NLM ISO Abbreviation: Front Chem Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Lausanne : Frontiers Media S.A., [2013]- |
| مستخلص: | Matrine is an alkaloid extracted from traditional Chinese herbs including Sophora flavescentis , Sophora alopecuroides , Sophora root, etc. It has the dual advantages of traditional Chinese herbs and chemotherapy drugs. It exhibits distinct benefits in preventing and improving chronic diseases such as cardiovascular disease and tumors. The review introduced recent research progresses on extraction, synthesis and derivatization of Matrine. The summary focused on the latest research advances of Matrine on anti-atherosclerosis, anti-hypertension, anti-ischemia reperfusion injury, anti-arrhythmia, anti-diabetic cardiovascular complications, anti-tumor, anti-inflammatory, anti-bacterium, anti-virus, which would provide new core structures and new insights for new drug development in related fields. Competing Interests: Authors A-HL and H-LC are employed by Shaanxi Pharmaceutical Holding Group Co., LTD, China. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2022 Sun, Jia, Rong, Zhou, Cao, Li, Guo, Jin, Wang, Huang, Li, He, Li, Ma, Lv, Shao, Zhang and Cao.) |
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| فهرسة مساهمة: | Keywords: derivatization; extraction; matrine; molecular mechanism; pharmacological effects; synthesis |
| تواريخ الأحداث: | Date Created: 20220418 Latest Revision: 20220716 |
| رمز التحديث: | 20221213 |
| مُعرف محوري في PubMed: | PMC9010661 |
| DOI: | 10.3389/fchem.2022.867318 |
| PMID: | 35433636 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2296-2646 |
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| DOI: | 10.3389/fchem.2022.867318 |