دورية أكاديمية
Randomized, double-blind clinical trial comparing the healing of stasis ulcers in lower limbs with standard hydrocolloid gel dressings and with dressings with Syzygium cumini extract.
| العنوان: | Randomized, double-blind clinical trial comparing the healing of stasis ulcers in lower limbs with standard hydrocolloid gel dressings and with dressings with Syzygium cumini extract. |
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| المؤلفون: | Araújo GR; Faculty of Health Science, Federal District Health Department, Vascular Surgery, 28127University of Brasília, Brasília, Brazil., Teles BSBS; Faculty of Health Science, Federal District Health Department, Vascular Surgery, 28127University of Brasília, Brasília, Brazil., Xoteslem GC; Vascular Surgery, 67839Secretary of State for Health of the Federal District, Brasília, Brazil., Gratieri T; Laboratory of Food, Drugs, and Cosmetics (LTMAC), 28127University of Brasília, Brasília, Brazil., Fortes RC; School of Health Sciences (ESCS), 67839Secretary of State for Health of the Federal District, Brasília, Brazil., Novaes MR; Faculty of Health Science, Federal District Health Department, Vascular Surgery, 28127University of Brasília, Brasília, Brazil. |
| المصدر: | Phlebology [Phlebology] 2022 Jul; Vol. 37 (6), pp. 460-468. Date of Electronic Publication: 2022 Apr 25. |
| نوع المنشور: | Journal Article; Randomized Controlled Trial |
| اللغة: | English |
| بيانات الدورية: | Publisher: Sage Country of Publication: England NLM ID: 9012921 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1758-1125 (Electronic) Linking ISSN: 02683555 NLM ISO Abbreviation: Phlebology Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Oct. 2012- : London : Sage Original Publication: [Houndmills, Basingstoke, Hampshire, UK] : Scientific & Medical, Macmillan Press, |
| مواضيع طبية MeSH: | Syzygium* , Varicose Ulcer*, Bandages, Hydrocolloid ; Colloids ; Humans ; Lower Extremity ; Occlusive Dressings ; Prospective Studies ; Quality of Life ; Wound Healing |
| مستخلص: | Objective: To evaluate the healing of venous ulcers in the lower limbs (VLU) using dressings with hydrocolloid gel associated with Syzygium cumini extract (SHG) compared to standard hydrocolloid gel dressings (HG). Method: This prospective, double-blind, randomized trial recruited 90 patients with VLU divided into: dressings with SHG ( n = 44) and dressings with HG ( n = 46). Primary endpoint was healing in the 14th visit. Secondary endpoints were healing rate, complete healing during follow-up, and improvement in the pain scale and in quality of life. Results: There were no significant between-group differences in healing ( p = 0.15). The wound area made healing difficult ( p = 0.008). Age, body mass index, and wound time demonstrated a tendency to worsen the healing. Positive culture for Pseudomonas aeruginosa resulted in 88% reduction in the healing risk ( p < 0.0001). Conclusion: There was no difference between the dressings evaluated. The presence of Pseudomonas aeruginosa significantly impaired wound healing. |
| فهرسة مساهمة: | Keywords: Leg ulcers; venous disease; venous ulceration; wound care |
| المشرفين على المادة: | 0 (Colloids) |
| تواريخ الأحداث: | Date Created: 20220425 Date Completed: 20220706 Latest Revision: 20220706 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1177/02683555221088380 |
| PMID: | 35466808 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1758-1125 |
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| DOI: | 10.1177/02683555221088380 |