دورية أكاديمية
Infection profile of patients with extracorporeal membrane oxygenation in paediatric cardiac surgery ICU.
| العنوان: | Infection profile of patients with extracorporeal membrane oxygenation in paediatric cardiac surgery ICU. |
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| المؤلفون: | Işık ME; Department of Infectious Diseases, Kartal Kosuyolu Training and Research Hospital, İstanbul, Turkey., Arslanoğlu E; Department of Pediatric Cardiovascular Surgery, Kartal Kosuyolu Training and Research Hospital, İstanbul, Turkey., Menekşe Ş; Department of Infectious Diseases, Kartal Kosuyolu Training and Research Hospital, İstanbul, Turkey., Uygun-Kızmaz Y; Department of Infectious Diseases, Kartal Kosuyolu Training and Research Hospital, İstanbul, Turkey., Şavluk ÖF; Department of Anesthesiology and Reanimation, Kartal Kosuyolu Training and Research Hospital, İstanbul, Turkey., Kara KA; Department of Pediatric Cardiovascular Surgery, Kartal Kosuyolu Training and Research Hospital, İstanbul, Turkey., Türkmen-Karaağaç A; Department of Pediatric, Kartal Kosuyolu Training and Research Hospital, İstanbul, Turkey., Ceyran H; Department of Pediatric Cardiovascular Surgery, Kartal Kosuyolu Training and Research Hospital, İstanbul, Turkey. |
| المصدر: | Cardiology in the young [Cardiol Young] 2022 Nov; Vol. 32 (11), pp. 1833-1838. Date of Electronic Publication: 2022 Apr 28. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Cambridge University Press Country of Publication: England NLM ID: 9200019 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1467-1107 (Electronic) Linking ISSN: 10479511 NLM ISO Abbreviation: Cardiol Young Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2005->: Cambridge : Cambridge University Press Original Publication: Chapel Hill, NC : World Publishers, c1991- |
| مواضيع طبية MeSH: | Extracorporeal Membrane Oxygenation*/adverse effects , Extracorporeal Membrane Oxygenation*/methods , Cardiac Surgical Procedures*/adverse effects , Cross Infection*/etiology , Cross Infection*/microbiology, Humans ; Child ; Retrospective Studies ; Intensive Care Units, Pediatric ; Length of Stay ; Risk Factors |
| مستخلص: | Aim: We investigated the risk of increased nosocomial infections and the associated pathogens in patients who underwent paediatric cardiovascular surgery and were put on extracorporeal membrane oxygenation support. We studied the duration of extracorporeal membrane oxygenation use and other variables that may be associated with increased nosocomial infection risk. Methods: Patients who were treated with an extracorporeal membrane oxygenation in paediatric cardiovascular surgery ICU between 2010 and 2020 were included in this retrospective study. We analysed the site of infection and microbiological profile of infections occurring in these patients according to CDC and National Healthcare Safety Network criteria. Results: The onset of infection development in patients after extracorporeal membrane oxygenation was found to be median 8 (3-15, 25-75 IQR) days in the whole group, and median 11 (3-16, 25-75 IQR) days in those who developed infection without being put on extracorporeal membrane oxygenation. When patients were divided into those with and without infection, duration of ICU was found to be 19 (16-28, IQR 25-75) days in patients with infection vs. 8 (2-16, IQR 25-75; p: <0.001) days in patients without infection. Duration of extracorporeal membrane oxygenation support was found to be 14 (10-25, IQR 25-75) days in patients with infection versus 5 (2-10, IQR 25-75; p: <0.001) days in patients without infection and total hospital stay was 26 (18-33, IQR 25-75) days in patients with infection versus 8 (2-23, IQR 25-75) days in those without infection. A total of 24 patients out of the 70 patients experienced 32 infectious episodes during extracorporeal membrane oxygenation support. Culture-positive infections were detected at a single site in 19 patients, and multiple sites in 5 patients. Conclusion: We propose that prolonged extracorporeal membrane oxygenation support is associated with an increased risk of infection. Although extracorporeal membrane oxygenation is a life-saving treatment method, prolonged extracorporeal membrane oxygenation may increase the development of infectious complications and the associated mortality and morbidity of the patient. |
| فهرسة مساهمة: | Keywords: Extracorporeal membrane oxygenation; nosocomial infections; pediatric cardiovascular surgery |
| تواريخ الأحداث: | Date Created: 20220428 Date Completed: 20221115 Latest Revision: 20221115 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1017/S1047951122001263 |
| PMID: | 35481466 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1467-1107 |
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| DOI: | 10.1017/S1047951122001263 |