دورية أكاديمية
Metal-free S -arylation of 5-mercaptotetrazoles and 2-mercaptopyridine with unsymmetrical diaryliodonium salts.
| العنوان: | Metal-free S -arylation of 5-mercaptotetrazoles and 2-mercaptopyridine with unsymmetrical diaryliodonium salts. |
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| المؤلفون: | Saikia RA; Department of Chemical Sciences, Tezpur University, Napaam-784028, Assam, India. ashim@tezu.ernet.in., Hazarika N; Department of Chemistry, Indian Institute of Technology Guwahati, North Guwahati-781039, India., Biswakarma N; Department of Chemical Sciences, Tezpur University, Napaam-784028, Assam, India. ashim@tezu.ernet.in., Chandra Deka R; Department of Chemical Sciences, Tezpur University, Napaam-784028, Assam, India. ashim@tezu.ernet.in., Thakur AJ; Department of Chemical Sciences, Tezpur University, Napaam-784028, Assam, India. ashim@tezu.ernet.in. |
| المصدر: | Organic & biomolecular chemistry [Org Biomol Chem] 2022 May 18; Vol. 20 (19), pp. 3890-3896. Date of Electronic Publication: 2022 May 18. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101154995 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-0539 (Electronic) Linking ISSN: 14770520 NLM ISO Abbreviation: Org Biomol Chem Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Cambridge, UK : Royal Society of Chemistry, c2003- |
| مواضيع طبية MeSH: | Onium Compounds* , Salts*, Metals ; Molecular Structure ; Pyridines ; Sulfhydryl Compounds |
| مستخلص: | Herein, we demonstrate the application of unsymmetrical iodonium salts towards S -arylation of heterocyclic thiols (especially tetrazole-5-thiols and pyridine-2-thiol) under metal-free conditions, affording a diverse range of di(hetero)aryl thioethers in moderate to good yields. A detailed study on the effects of counter-anions and the auxiliary of iodonium salts was conducted. Suitable auxiliary selection of the unsymmetrical iodonium salt offers flexibility for a wide range of aryl moieties and its incorporation into S -arylation. The DFT study supports the experimental observations of chemoselective arylation. |
| المشرفين على المادة: | 0 (Metals) 0 (Onium Compounds) 0 (Pyridines) 0 (Salts) 0 (Sulfhydryl Compounds) EE982KT952 (2-thiopyridine) |
| تواريخ الأحداث: | Date Created: 20220428 Date Completed: 20220519 Latest Revision: 20220601 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1039/d2ob00406b |
| PMID: | 35481589 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1477-0539 |
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| DOI: | 10.1039/d2ob00406b |