دورية أكاديمية
أعرض في EDS

Portable air cleaners and residential exposure to SARS-CoV-2 aerosols: A real-world study.

التفاصيل البيبلوغرافية
العنوان: Portable air cleaners and residential exposure to SARS-CoV-2 aerosols: A real-world study.
المؤلفون: Myers NT; Department of Environmental Sciences, Rutgers University, New Brunswick, New Jersey, USA.; Rutgers Environmental and Occupational Health Sciences Institute, Rutgers University, Piscataway, New Jersey, USA., Laumbach RJ; Rutgers Environmental and Occupational Health Sciences Institute, Rutgers University, Piscataway, New Jersey, USA.; Department of Environmental and Occupational Health and Justice, Rutgers University, Piscataway, New Jersey, USA., Black KG; Rutgers Environmental and Occupational Health Sciences Institute, Rutgers University, Piscataway, New Jersey, USA., Ohman-Strickland P; Rutgers Environmental and Occupational Health Sciences Institute, Rutgers University, Piscataway, New Jersey, USA.; Department of Biostatistics and Epidemiology, Rutgers School of Public Health, Rutgers University, Piscataway, New Jersey, USA., Alimokhtari S; Rutgers Environmental and Occupational Health Sciences Institute, Rutgers University, Piscataway, New Jersey, USA., Legard A; Rutgers Environmental and Occupational Health Sciences Institute, Rutgers University, Piscataway, New Jersey, USA., De Resende A; Rutgers Environmental and Occupational Health Sciences Institute, Rutgers University, Piscataway, New Jersey, USA., Calderón L; Department of Environmental Sciences, Rutgers University, New Brunswick, New Jersey, USA.; Rutgers Environmental and Occupational Health Sciences Institute, Rutgers University, Piscataway, New Jersey, USA., Lu FT; Rutgers Environmental and Occupational Health Sciences Institute, Rutgers University, Piscataway, New Jersey, USA., Mainelis G; Department of Environmental Sciences, Rutgers University, New Brunswick, New Jersey, USA.; Rutgers Environmental and Occupational Health Sciences Institute, Rutgers University, Piscataway, New Jersey, USA., Kipen HM; Rutgers Environmental and Occupational Health Sciences Institute, Rutgers University, Piscataway, New Jersey, USA.; Department of Environmental and Occupational Health and Justice, Rutgers University, Piscataway, New Jersey, USA.
المصدر: Indoor air [Indoor Air] 2022 Apr; Vol. 32 (4), pp. e13029.
نوع المنشور: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
اللغة: English
بيانات الدورية: Publisher: Blackwell Country of Publication: England NLM ID: 9423515 Publication Model: Print Cited Medium: Internet ISSN: 1600-0668 (Electronic) Linking ISSN: 09056947 NLM ISO Abbreviation: Indoor Air Subsets: MEDLINE
أسماء مطبوعة: Publication: Oxford : Blackwell
Original Publication: Copenhagen : Danish Technical Press, c1991-
مواضيع طبية MeSH: Air Pollution, Indoor*/analysis , COVID-19*, Aerosols ; Humans ; RNA, Viral ; SARS-CoV-2 ; Single-Blind Method
مستخلص: Individuals with COVID-19 who do not require hospitalization are instructed to self-isolate in their residences. Due to high secondary infection rates in household members, there is a need to understand airborne transmission of SARS-CoV-2 within residences. We report the first naturalistic intervention study suggesting a reduction of such transmission risk using portable air cleaners (PACs) with HEPA filters. Seventeen individuals with newly diagnosed COVID-19 infection completed this single-blind, crossover, randomized study. Total and size-fractionated aerosol samples were collected simultaneously in the self-isolation room with the PAC (primary) and another room (secondary) for two consecutive 24-h periods, one period with HEPA filtration and the other with the filter removed (sham). Seven out of sixteen (44%) air samples in primary rooms were positive for SARS-CoV-2 RNA during the sham period. With the PAC operated at its lowest setting (clean air delivery rate [CADR] = 263 cfm) to minimize noise, positive aerosol samples decreased to four out of sixteen residences (25%; p = 0.229). A slight decrease in positive aerosol samples was also observed in the secondary room. As the world confronts both new variants and limited vaccination rates, our study supports this practical intervention to reduce the presence of viral aerosols in a real-world setting.
(© 2022 The Authors. Indoor Air published by John Wiley & Sons Ltd.)
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معلومات مُعتمدة: T32 ES007148 United States ES NIEHS NIH HHS; T42OH008422 United States ACL ACL HHS; UL1TR003017 NIH/CATS
فهرسة مساهمة: Keywords: Air change rate; Airborne transmission; COVID-19 pandemic; COVID-19 symptoms; PTFE filter virus sampling; SARS-CoV-2 aerosols
المشرفين على المادة: 0 (Aerosols)
0 (RNA, Viral)
تواريخ الأحداث: Date Created: 20220428 Date Completed: 20220502 Latest Revision: 20230916
رمز التحديث: 20230916
مُعرف محوري في PubMed: PMC9111720
DOI: 10.1111/ina.13029
PMID: 35481935
قاعدة البيانات: MEDLINE
الوصف
تدمد:1600-0668
DOI:10.1111/ina.13029