دورية أكاديمية
[A clinical study of thunder-fire moxibustion combined with meibomian gland massage in treatment of meibomian gand dysfunction].
| العنوان: | [A clinical study of thunder-fire moxibustion combined with meibomian gland massage in treatment of meibomian gand dysfunction]. |
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| المؤلفون: | Qian LJ; Nanjing University of Chinese Medicine, Nanjing 210029,China; Jinhua Hospital of Traditional Chinese Medicine Affiliated to Zhejiang Chinese Medical University, Jinhua 321017, Zhejiang Province., Ying WM; Jinhua Hospital of Traditional Chinese Medicine Affiliated to Zhejiang Chinese Medical University, Jinhua 321017, Zhejiang Province., Zhou GZ; Jinhua Hospital of Traditional Chinese Medicine Affiliated to Zhejiang Chinese Medical University, Jinhua 321017, Zhejiang Province., Wei W; Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029. |
| المصدر: | Zhen ci yan jiu = Acupuncture research [Zhen Ci Yan Jiu] 2022 Apr 25; Vol. 47 (4), pp. 349-53. |
| نوع المنشور: | Journal Article; Randomized Controlled Trial |
| اللغة: | Chinese |
| بيانات الدورية: | Publisher: Institute Of Acupuncture And Moxibustion Country of Publication: China NLM ID: 8507710 Publication Model: Print Cited Medium: Print ISSN: 1000-0607 (Print) Linking ISSN: 10000607 NLM ISO Abbreviation: Zhen Ci Yan Jiu Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Beijing : Institute Of Acupuncture And Moxibustion Original Publication: Beijing, China : Published and distributed by World Books, [1980- |
| مواضيع طبية MeSH: | Meibomian Glands* , Moxibustion*, Dinoprostone ; Humans ; Interleukin-6 ; Massage ; Ophthalmic Solutions ; Prospective Studies |
| مستخلص: | Objective: To observe the effect of thunder-fire moxibustion combined with meibomian gland massage in improving meibomian gland dysfunction (MGD) and explore its mechanism. Methods: Seventy-two MGD patients with 144 eyes in the Jinhua Hospital of Traditional Chinese Medicine from February 2019 to January 2021 were selected and randomly divided into an experimental group ( n =36,72 eyes) and a control group ( n =36, 72 eyes). Patients in the control group received 0.1% fluo-rometholone eye drops and 0.1% sodium hyaluronate eye drops, 1-2 drops per time, four times per day, and the meibomian glands were massaged once per day. Patients in the experimental group received additional thunder-fire moxibustion on the basis of the treatment of the control group, 10 cones per time, once per day. One month after treatment, meibomian gland function was assessed, and the levels of interleukin-6 (IL-6) and prostaglandin E2(PGE2) in tears were detected. Results: After treatment, the scores of Ocular Surface Disease Index, meibomian hyperemia, meibomian gland opening, meibomian gland loss, and meibomian gland secretion function were lower than those before treatment in the two groups, and the scores of the experimental group were lower than those of the control group ( P <0.05). After treatment, the tear break-up time and tear meniscus height were higher than those before treatment in the two groups, which were higher in the experimental group than those in the control group ( P <0.05). The post-treatment levels of IL-6 and PGE2 were lower than those before treatment in the two groups, and the levels in the experimental group were lower than those in the control group ( P <0.05). Conclusion: Thunder-fire moxibustion combined with meibomian gland massage can significantly improve the function of the meibomian glands and lower the levels of IL-6 and PGE |
| فهرسة مساهمة: | Keywords: Interleukin-6 (IL-6); Meibomian gland dysfunction (MGD); Meibomian gland massage; Prostaglandin E2(PGE2); Thunder-fire moxibustion Local Abstract: [Publisher, Chinese] 目的： 观察雷火灸联合睑板腺按摩对睑板腺功能障碍(MGD)的改善作用，分析其作用机制。 方法： MGD患者72例144眼随机分为试验组和对照组，各36例72眼。对照组患者给予0.1%氟米龙滴眼液+0.1%玻璃酸钠滴眼液，4次/d，1～2滴/次，并每日1次按摩睑板腺；在对照组治疗的基础上，对试验组患者双眼进行雷火灸，每次灸10壮，每日1次。治疗1个月后，评估睑板腺功能，检测泪液白细胞介素-6(IL-6)与前列腺素E |
| المشرفين على المادة: | 0 (Interleukin-6) 0 (Ophthalmic Solutions) K7Q1JQR04M (Dinoprostone) |
| تواريخ الأحداث: | Date Created: 20220429 Date Completed: 20220503 Latest Revision: 20220531 |
| رمز التحديث: | 20231215 |
| DOI: | 10.13702/j.1000-0607.20210963 |
| PMID: | 35486015 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1000-0607 |
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| DOI: | 10.13702/j.1000-0607.20210963 |