دورية أكاديمية
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Simulation of Mechanical Heart Valve Dysfunction and the Non-Newtonian Blood Model Approach.

التفاصيل البيبلوغرافية
العنوان: Simulation of Mechanical Heart Valve Dysfunction and the Non-Newtonian Blood Model Approach.
المؤلفون: Chen A; Faculty of Engineering, Universiti Putra Malaysia, Serdang, Selangor 43400, Malaysia., Basri AAB; Faculty of Engineering, Universiti Putra Malaysia, Serdang, Selangor 43400, Malaysia., Ismail NB; Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor 43400, Malaysia., Tamagawa M; Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology, Kitakyushu, Fukuoka 804-8550, Japan., Zhu D; Faculty of Engineering, Universiti Putra Malaysia, Serdang, Selangor 43400, Malaysia., Ahmad KA; Faculty of Engineering, Universiti Putra Malaysia, Serdang, Selangor 43400, Malaysia.
المصدر: Applied bionics and biomechanics [Appl Bionics Biomech] 2022 Apr 19; Vol. 2022, pp. 9612296. Date of Electronic Publication: 2022 Apr 19 (Print Publication: 2022).
نوع المنشور: Journal Article; Review; Retracted Publication
اللغة: English
بيانات الدورية: Publisher: Hindawi Publishing Corporation Country of Publication: Egypt NLM ID: 101208624 Publication Model: eCollection Cited Medium: Print ISSN: 1176-2322 (Print) Linking ISSN: 11762322 NLM ISO Abbreviation: Appl Bionics Biomech Subsets: PubMed not MEDLINE
أسماء مطبوعة: Publication: <2014-> : Cairo : Hindawi Publishing Corporation
Original Publication: 2003-2004: Auckland, N.Z. : Open Mind Journals
مستخلص: The mechanical heart valve (MHV) is commonly used for the treatment of cardiovascular diseases. Nonphysiological hemodynamic in the MHV may cause hemolysis, platelet activation, and an increased risk of thromboembolism. Thromboembolism may cause severe complications and valve dysfunction. This paper thoroughly reviewed the simulation of physical quantities (velocity distribution, vortex formation, and shear stress) in healthy and dysfunctional MHV and reviewed the non-Newtonian blood flow characteristics in MHV. In the MHV numerical study, the dysfunction will affect the simulation results, increase the pressure gradient and shear stress, and change the blood flow patterns, increasing the risks of hemolysis and platelet activation. The blood flow passes downstream and has obvious recirculation and stagnation region with the increased dysfunction severity. Due to the complex structure of the MHV, the non-Newtonian shear-thinning viscosity blood characteristics become apparent in MHV simulations. The comparative study between Newtonian and non-Newtonian always shows the difference. The shear-thinning blood viscosity model is the basics to build the blood, also the blood exhibiting viscoelastic properties. More details are needed to establish a complete and more realistic simulation.
Competing Interests: The authors declared that they have no conflicts of interest regarding this work.
(Copyright © 2022 Aolin Chen et al.)
التعليقات: Retraction in: Appl Bionics Biomech. 2023 Nov 29;2023:9896350. (PMID: 38075140)
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تواريخ الأحداث: Date Created: 20220502 Latest Revision: 20231211
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC9042627
DOI: 10.1155/2022/9612296
PMID: 35498142
قاعدة البيانات: MEDLINE
الوصف
تدمد:1176-2322
DOI:10.1155/2022/9612296