Hospital Pharmacists Interventions to Drug-Related Problems at Tertiary Critical Care Pediatric Settings in Jazan, Saudi Arabia.

التفاصيل البيبلوغرافية
العنوان:	Hospital Pharmacists Interventions to Drug-Related Problems at Tertiary Critical Care Pediatric Settings in Jazan, Saudi Arabia.
المؤلفون:	Tawhari MM; Pharmaceutical Care Deprtment, King Fahad Central Hospital, Jazan Health Affairs, Ministry of Health, Jazan, Saudi Arabia., Tawhari MA; Pharmaceutical Care Deprtment, King Fahad Central Hospital, Jazan Health Affairs, Ministry of Health, Jazan, Saudi Arabia., Noshily MA; Pharmaceutical Care Deprtment, King Fahad Central Hospital, Jazan Health Affairs, Ministry of Health, Jazan, Saudi Arabia., Mathkur MH; Pharmaceutical Care Deprtment, King Fahad Central Hospital, Jazan Health Affairs, Ministry of Health, Jazan, Saudi Arabia., Abutaleb MH; Pharmaceutical Care Deprtment, King Fahad Central Hospital, Jazan Health Affairs, Ministry of Health, Jazan, Saudi Arabia.
المصدر:	Hospital pharmacy [Hosp Pharm] 2022 Feb; Vol. 57 (1), pp. 146-153. Date of Electronic Publication: 2021 Feb 06.
نوع المنشور:	Journal Article
اللغة:	English
بيانات الدورية:	Publisher: Sage Publications Country of Publication: United States NLM ID: 0043175 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0018-5787 (Print) Linking ISSN: 00185787 NLM ISO Abbreviation: Hosp Pharm Subsets: PubMed not MEDLINE
أسماء مطبوعة:	Publication: <2017-> : Thousand Oaks, CA : Sage Publications Original Publication: [Philadelphia] : Lippincott
مستخلص:	Background: While drug-related problems (DRPs) have been recognized as a major concern in pediatric wards, the role of hospital pharmacy in improving medication safety has been rarely studied. Objectives: To investigate the frequency, nature, and severity of DRPs and associated pharmacist interventions (PIs). Methods: This is a prospective study carried out using direct observation over a year (2019-2020) in 3 pediatric wards (pediatric emergency department (PED), pediatric intensive care unit (PICU), and neonatal intensive care unit (NICU) in Jazan, Saudi Arabia. A validated data reporting form was developed to include comprehensive clinical data about the prescribed medications, characteristics of patients, and PIs upon DRPs. Clinical significance of DRPs was evaluated by an expert panel, which comprised a clinical pharmacist, a pediatrician, and an internist. Data analysis was conducted using SPSS V26. Results: The overall incidence of DRPs was 6.6%. The highest rate of DRPs 15.2% was detected in the pediatric ICU. Of the 596 DRPs detected, 10.2% were inappropriate drug choice, 5.2% were rated major DRPs, and one-third 33.2% were related to the digestive system and metabolism. Dosing problems were the most predominant DRPs across the included wards. A higher proportion of clinically major and moderate DRPs were detected in pediatric ED. Telephone-delivered interventions [OR: 1.72: 95%CI: 0.78-2.57: P = .001], too high dose [OR: 2.64: 95%CI: 1.33-4.56: P = .01], and major DRPs [OR: 3.21: 95%CI: 2.15-6.42: P = .04] were significant predictors for acceptance of PIs. Conclusion: DRPs are common in Saudi pediatric wards and many of these incidents were clinically major and moderate. Telephone-delivered interventions, too high dose, and major DRPs were major predictors for physician acceptance of PIs. Competing Interests: Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. (© The Author(s) 2021.)
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فهرسة مساهمة:	Keywords: Drug-related problems; pediatric; pharmacist
تواريخ الأحداث:	Date Created: 20220506 Latest Revision: 20230202
رمز التحديث:	20231215
مُعرف محوري في PubMed:	PMC9065537
DOI:	10.1177/0018578721990889
PMID:	35521004
قاعدة البيانات:	MEDLINE

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تدمد:	0018-5787
DOI:	10.1177/0018578721990889