دورية أكاديمية
أعرض في EDS

α-Hydroxy acid as an aldehyde surrogate: metal-free synthesis of pyrrolo[1,2- a ]quinoxalines, quinazolinones, and other N-heterocycles via decarboxylative oxidative annulation reaction.

التفاصيل البيبلوغرافية
العنوان: α-Hydroxy acid as an aldehyde surrogate: metal-free synthesis of pyrrolo[1,2- a ]quinoxalines, quinazolinones, and other N-heterocycles via decarboxylative oxidative annulation reaction.
المؤلفون: Viji M; College of Pharmacy, Medicinal Research Center (MRC), Chungbuk National University Cheongju 28160 Republic of Korea orgjkjung@chungbuk.ac.kr +82-43-268-2732 +82-43-261-2635., Vishwanath M; College of Pharmacy, Medicinal Research Center (MRC), Chungbuk National University Cheongju 28160 Republic of Korea orgjkjung@chungbuk.ac.kr +82-43-268-2732 +82-43-261-2635., Sim J; College of Pharmacy, Medicinal Research Center (MRC), Chungbuk National University Cheongju 28160 Republic of Korea orgjkjung@chungbuk.ac.kr +82-43-268-2732 +82-43-261-2635., Park Y; College of Pharmacy, Medicinal Research Center (MRC), Chungbuk National University Cheongju 28160 Republic of Korea orgjkjung@chungbuk.ac.kr +82-43-268-2732 +82-43-261-2635., Jung C; College of Pharmacy, Medicinal Research Center (MRC), Chungbuk National University Cheongju 28160 Republic of Korea orgjkjung@chungbuk.ac.kr +82-43-268-2732 +82-43-261-2635., Lee S; College of Pharmacy, Medicinal Research Center (MRC), Chungbuk National University Cheongju 28160 Republic of Korea orgjkjung@chungbuk.ac.kr +82-43-268-2732 +82-43-261-2635., Lee H; College of Pharmacy, Medicinal Research Center (MRC), Chungbuk National University Cheongju 28160 Republic of Korea orgjkjung@chungbuk.ac.kr +82-43-268-2732 +82-43-261-2635., Lee K; College of Pharmacy, Korea University Sejong 30019 Republic of Korea., Jung JK; College of Pharmacy, Medicinal Research Center (MRC), Chungbuk National University Cheongju 28160 Republic of Korea orgjkjung@chungbuk.ac.kr +82-43-268-2732 +82-43-261-2635.
المصدر: RSC advances [RSC Adv] 2020 Oct 07; Vol. 10 (61), pp. 37202-37208. Date of Electronic Publication: 2020 Oct 07 (Print Publication: 2020).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101581657 Publication Model: eCollection Cited Medium: Internet ISSN: 2046-2069 (Electronic) Linking ISSN: 20462069 NLM ISO Abbreviation: RSC Adv Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Cambridge [England] : Royal Society of Chemistry, [2011]-
مستخلص: A metal-free and efficient procedure for the synthesis of pyrrolo[1,2- a ]quinoxalines, quinazolinones, and indolo[1,2- a ]quinoxaline has been developed. The key features of our method include the in situ generation of aldehyde from α-hydroxy acid in the presence of TBHP ( tert -butyl hydrogen peroxide), and further condensation with various amines, followed by intramolecular cyclization and subsequent oxidation to afford the corresponding quinoxalines, quinazolinones derivatives in moderate to high yields.
Competing Interests: There are no conflicts to declare.
(This journal is © The Royal Society of Chemistry.)
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تواريخ الأحداث: Date Created: 20220506 Latest Revision: 20220716
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC9057147
DOI: 10.1039/d0ra07093a
PMID: 35521290
قاعدة البيانات: MEDLINE
الوصف
تدمد:2046-2069
DOI:10.1039/d0ra07093a