دورية أكاديمية
Prospectively Assessed Long-Term Outcomes of Patients with E-Cigarette- or Vaping-associated Lung Injury.
| العنوان: | Prospectively Assessed Long-Term Outcomes of Patients with E-Cigarette- or Vaping-associated Lung Injury. |
|---|---|
| المؤلفون: | Blagev DP; Pulmonary and Critical Care Medicine Division, Department of Medicine.; Department of Research.; Division of Pulmonary & Critical Care Medicine, Department of Medicine, University of Utah, Salt Lake City, Utah; and., Callahan SJ; Division of Pulmonary & Critical Care Medicine, Department of Medicine, University of Utah, Salt Lake City, Utah; and., Harris D; Pulmonary and Critical Care Medicine Division, Department of Medicine.; Telecritical Care Division, Department of Intermountain Telehealth, and., Collingridge DS; Department of Research., Hopkins RO; Neuroscience Center, Department of Psychology, Brigham Young University, Provo, Utah., Eve JR; Enterprise Analytics, Intermountain Healthcare, Salt Lake City, Utah., Waddoups L; Division of Pulmonary & Critical Care Medicine, Department of Medicine, University of Utah, Salt Lake City, Utah; and., Aston V; Department of Research., Brown S; Pulmonary and Critical Care Medicine Division, Department of Medicine.; Department of Research.; Division of Pulmonary & Critical Care Medicine, Department of Medicine, University of Utah, Salt Lake City, Utah; and., Lanspa MJ; Pulmonary and Critical Care Medicine Division, Department of Medicine.; Department of Research.; Division of Pulmonary & Critical Care Medicine, Department of Medicine, University of Utah, Salt Lake City, Utah; and. |
| المصدر: | Annals of the American Thoracic Society [Ann Am Thorac Soc] 2022 Nov; Vol. 19 (11), pp. 1892-1899. |
| نوع المنشور: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: American Thoracic Society Country of Publication: United States NLM ID: 101600811 Publication Model: Print Cited Medium: Internet ISSN: 2325-6621 (Electronic) Linking ISSN: 23256621 NLM ISO Abbreviation: Ann Am Thorac Soc Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: New York, NY : American Thoracic Society, [2013]- |
| مواضيع طبية MeSH: | Vaping*/adverse effects , Electronic Nicotine Delivery Systems* , Lung Injury*/etiology , COVID-19* , Respiration Disorders*, Adolescent ; Humans ; Male ; Young Adult ; Adult ; Female ; Lung |
| مستخلص: | Rationale: E-cigarette- or vaping-associated lung injury (EVALI) was first identified in 2019. The long-term respiratory, cognitive, mood disorder, and vaping behavior outcomes of patients with EVALI remain unknown. Objectives: To determine the long-term respiratory, cognitive, mood disorder, and vaping behavior outcomes of patients with EVALI. Methods: We prospectively enrolled patients with EVALI from two health systems. We assessed outcomes at 1 year after onset of EVALI using validated instruments measuring cognitive function, depression, anxiety, post-traumatic stress, respiratory disability, coronavirus disease (COVID-19) infection, pulmonary function, and vaping behaviors. We used multivariable regression to identify risk factors of post-EVALI vaping behaviors and to identify whether admission to the intensive care unit (ICU) was associated with cognitive, respiratory, or mood symptoms. Results: Seventy-three patients completed 12-month follow-up. Most patients were male (66.7%), young (mean age, 31 ± 11 yr), and White (85%) and did not need admission to the ICU (59%). At 12 months, 39% (25 of 64) had cognitive impairment, whereas 48% (30 of 62) reported respiratory limitations. Mood disorders were common, with 59% (38 of 64) reporting anxiety and/or depression and 62% (39 of 63) having post-traumatic stress. Four (6.4%) of 64 reported a history of COVID-19 infection. Despite the history of EVALI, many people continued to vape. Only 38% (24 of 64) reported quitting all vaping and smoking behaviors. Younger age was associated with reduced vaping behavior after EVALI (odds ratio, 0.93; P = 0.02). ICU admission was not associated with cognitive impairment, dyspnea, or mood symptoms. Conclusions: Patients with EVALI, despite their youth, commonly have significant long-term respiratory disability; cognitive impairment; symptoms of depression, anxiety, post-traumatic stress; and persistent vaping. |
| التعليقات: | Comment in: Ann Am Thorac Soc. 2022 Nov;19(11):1805-1807. (PMID: 36318078) |
| References: | J Cancer Surviv. 2011 Sep;5(3):305-14. (PMID: 21274648) JAMA. 1999 Jan 27;281(4):354-60. (PMID: 9929089) Int J Chron Obstruct Pulmon Dis. 2016 May 18;11:1045-52. (PMID: 27274226) Am J Respir Crit Care Med. 2003 Mar 1;167(5):690-4. (PMID: 12493646) JAMA. 2021 Apr 20;325(15):1525-1534. (PMID: 33729425) Am J Respir Crit Care Med. 2017 Nov 1;196(9):1122-1130. (PMID: 28537429) N Engl J Med. 2020 Feb 20;382(8):697-705. (PMID: 31860793) Crit Care. 2019 Aug 7;23(1):276. (PMID: 31391069) MMWR Morb Mortal Wkly Rep. 2019 Nov 29;68(47):1096-1100. (PMID: 31774740) MMWR Morb Mortal Wkly Rep. 2019 Nov 15;68(45):1040-1041. (PMID: 31725707) N Engl J Med. 2020 Mar 19;382(12):1175-1177. (PMID: 32101656) Am J Respir Crit Care Med. 2012 Jun 15;185(12):1307-15. (PMID: 22492988) Respir Med. 1991 Sep;85 Suppl B:25-31; discussion 33-7. (PMID: 1759018) JAMA Netw Open. 2021 Oct 1;4(10):e2128810. (PMID: 34665239) Lancet. 2019 Dec 7;394(10214):2073-2083. (PMID: 31711629) N Engl J Med. 2019 Oct 10;381(15):1488-1489. (PMID: 31491073) MMWR Morb Mortal Wkly Rep. 2019 Sep 13;68(36):787-790. (PMID: 31513561) N Engl J Med. 2013 Oct 3;369(14):1306-16. (PMID: 24088092) Crit Care Med. 2012 Feb;40(2):502-9. (PMID: 21946660) N Engl J Med. 2020 Mar 5;382(10):903-916. (PMID: 31491072) N Engl J Med. 2019 Oct 10;381(15):1486-1487. (PMID: 31491070) Intensive Care Med. 2018 Jan;44(1):38-47. (PMID: 29279973) Lancet Respir Med. 2021 Dec;9(12):e112-e113. (PMID: 34710356) Crit Care. 2019 Nov 19;23(1):362. (PMID: 31744551) JAMA. 2020 Nov 10;324(18):1835-1837. (PMID: 33170225) Ann Am Thorac Soc. 2018 Sep;15(9):1108-1110. (PMID: 30168744) |
| معلومات مُعتمدة: | U01 HL123018 United States HL NHLBI NIH HHS; UL1 TR002538 United States TR NCATS NIH HHS |
| فهرسة مساهمة: | Keywords: EVALI; e-cigarettes; e-cigarette– or vaping-associated lung injury; long-term outcome; vaping |
| تواريخ الأحداث: | Date Created: 20220509 Date Completed: 20221103 Latest Revision: 20231123 |
| رمز التحديث: | 20231123 |
| مُعرف محوري في PubMed: | PMC9667811 |
| DOI: | 10.1513/AnnalsATS.202201-049OC |
| PMID: | 35533314 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 2325-6621 |
|---|---|
| DOI: | 10.1513/AnnalsATS.202201-049OC |