دورية أكاديمية
أعرض في EDS

Predicting Residual Angina After Chronic Total Occlusion Percutaneous Coronary Intervention: Insights from the OPEN-CTO Registry.

التفاصيل البيبلوغرافية
العنوان: Predicting Residual Angina After Chronic Total Occlusion Percutaneous Coronary Intervention: Insights from the OPEN-CTO Registry.
المؤلفون: Butala NM; Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology Division of Cardiology Beth Israel Deaconess Medical Center Boston MA.; Division of Cardiology Massachusetts General Hospital Boston MA., Tamez H; Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology Division of Cardiology Beth Israel Deaconess Medical Center Boston MA., Secemsky EA; Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology Division of Cardiology Beth Israel Deaconess Medical Center Boston MA., Grantham JA; Saint Luke's Mid America Heart Institute/UMKC Kansas City MO., Spertus JA; Saint Luke's Mid America Heart Institute/UMKC Kansas City MO., Cohen DJ; Cardiovascular Research Foundation New York NY., Jones P; Saint Luke's Mid America Heart Institute/UMKC Kansas City MO., Salisbury AC; Saint Luke's Mid America Heart Institute/UMKC Kansas City MO., Arnold SV; Saint Luke's Mid America Heart Institute/UMKC Kansas City MO., Harrell F; Department of Biostatistics Vanderbilt University School of Medicine Nashville TN., Lombardi W; Division of Cardiology University of Washington Seattle WA., Karmpaliotis D; Columbia University Medical Center New York NY., Moses J; Columbia University Medical Center New York NY., Sapontis J; Monash Heart Melbourne Victoria Australia., Yeh RW; Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology Division of Cardiology Beth Israel Deaconess Medical Center Boston MA.
المصدر: Journal of the American Heart Association [J Am Heart Assoc] 2022 May 17; Vol. 11 (10), pp. e024056. Date of Electronic Publication: 2022 May 16.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-9980 (Electronic) Linking ISSN: 20479980 NLM ISO Abbreviation: J Am Heart Assoc Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Oxford : Wiley-Blackwell
مواضيع طبية MeSH: Coronary Occlusion*/complications , Coronary Occlusion*/diagnosis , Coronary Occlusion*/surgery , Percutaneous Coronary Intervention*/adverse effects, Angina Pectoris/etiology ; Chronic Disease ; Coronary Angiography ; Disease Progression ; Humans ; Nitroglycerin/therapeutic use ; Registries ; Risk Factors ; Time Factors ; Treatment Outcome
مستخلص: Background Given that percutaneous coronary intervention (PCI) of a chronic total occlusion (CTO) is indicated primarily for symptom relief, identifying patients most likely to benefit is critically important for patient selection and shared decision-making. Therefore, we identified factors associated with residual angina frequency after CTO PCI and developed a model to predict postprocedure anginal burden. Methods and Results Among patients in the OPEN-CTO (Outcomes, Patient Health Status, and Efficiency in Chronic Total Occlusion Hybrid Procedures) registry, we evaluated the association between patient characteristics and residual angina frequency at 6 months, as assessed by the Seattle Angina Questionnaire Angina Frequency Scale. We then constructed a prediction model for angina status after CTO PCI using ordinal regression. Among 901 patients undergoing CTO PCI, 28% had no angina, 31% had monthly angina, 30% had weekly angina, and 12% had daily angina at baseline. Six months later, 53% of patients had a ≥20-point increase in Seattle Angina Questionnaire Angina Frequency Scale score. The final model to predict residual angina after CTO PCI included baseline angina frequency, baseline nitroglycerin use frequency, dyspnea symptoms, depressive symptoms, number of antianginal medications, PCI indication, and presence of multiple CTO lesions and had a C index of 0.78. Baseline angina frequency and nitroglycerin use frequency explained 71% of the predictive power of the model, and the relationship between model components and angina improvement at 6 months varied by baseline angina status. Conclusions A 7-component OPEN-AP (OPEN-CTO Angina Prediction) score can predict angina improvement and residual angina after CTO PCI using variables commonly available before intervention. These findings have implications for appropriate patient selection and counseling for CTO PCI.
التعليقات: Comment in: J Am Heart Assoc. 2022 May 17;11(10):e026070. doi: 10.1161/JAHA.122.026070. (PMID: 35574966)
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معلومات مُعتمدة: K23 HL150290 United States HL NHLBI NIH HHS
فهرسة مساهمة: Keywords: angina; angina frequency; chronic total occlusion; patient selection; percutaneous coronary intervention; prediction; score
المشرفين على المادة: G59M7S0WS3 (Nitroglycerin)
تواريخ الأحداث: Date Created: 20220516 Date Completed: 20220519 Latest Revision: 20240725
رمز التحديث: 20240726
مُعرف محوري في PubMed: PMC9238547
DOI: 10.1161/JAHA.121.024056
PMID: 35574949
قاعدة البيانات: MEDLINE
الوصف
تدمد:2047-9980
DOI:10.1161/JAHA.121.024056