دورية أكاديمية
أعرض في EDS

Re-excision within a radius of 2 cm in patients with melanoma of the skin - sufficient for local oncological radicalness.

التفاصيل البيبلوغرافية
العنوان: Re-excision within a radius of 2 cm in patients with melanoma of the skin - sufficient for local oncological radicalness.
المؤلفون: Strashilov SA; Department of Plastic Restorative, Reconstructive and Aesthetic Surgery, University Hospital 'Dr. Georgi Stranski', Medical University Pleven, Pleven, Bulgaria., Yordanov AD; Clinic of Gynecologic Oncology, University Hospital 'Dr. Georgi Stranski', Medical University Pleven, Pleven, Bulgaria., Vasileva-Slaveva MB; Tyrolean Cancer Research Institute, Innsbruck, Austria., Konsoulova AA; Complex Oncological Center Burgas, Burgas, Bulgaria.
المصدر: Archives of medical science : AMS [Arch Med Sci] 2020 Jul 08; Vol. 18 (3), pp. 690-695. Date of Electronic Publication: 2020 Jul 08 (Print Publication: 2022).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Termedia Pub. House Country of Publication: Poland NLM ID: 101258257 Publication Model: eCollection Cited Medium: Print ISSN: 1734-1922 (Print) Linking ISSN: 17341922 NLM ISO Abbreviation: Arch Med Sci Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: [Poznań, Poland] : Termedia Pub. House, [2005]-
مستخلص: Introduction: Malignant melanoma is one of the most malignant tumours in the human body. Radical re-excision of the tumour bed is a principal part of its surgical treatment. We aim to test the hypothesis that the re-excision with a 2 cm margin in all directions to the scar from the previous biopsy of the primary tumour provides sufficient local control in patients with this disease.
Material and Methods: This is a prospective descriptive study using STROBE methods, including all 151 patients with malignant melanoma of the skin, diagnosed and treated at the Department of Plastic, Reconstructive, and Aesthetic Surgery, Dr Georgi Stranski University Hospital, Medical University of Pleven, Bulgaria, in the period 2012-2016. Twenty-one cases were omitted from the study during the observation period due to lack of sufficient data. The re-excision was mainly within 2 cm margins in all directions to the scar from the previous biopsy of the primary tumour.
Results: Data of all 130 patients with malignant skin melanoma, diagnosed and treated at our single large centre, were prospectively registered and analysed. These were 67 male and 63 female patients with a mean age at diagnosis of 61.6 years (range: 17-91 years). Using the re-excision within 2 cm margins, we identified only 1 (0.77%) patient with a histologically confirmed residual tumour in the re-excised flap. Local recurrence was observed in 13 (10%) patients.
Conclusions: Re-excision with a 2 cm margin is sufficient to achieve local surgical radicalness in the treatment of this disease without compromising oncological survival.
Competing Interests: The authors declare no conflict of interest.
(Copyright: © 2020 Termedia & Banach.)
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فهرسة مساهمة: Keywords: local recurrence; malignant melanoma; re-excision
تواريخ الأحداث: Date Created: 20220520 Latest Revision: 20220716
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC9103401
DOI: 10.5114/aoms.2020.97056
PMID: 35591818
قاعدة البيانات: MEDLINE
الوصف
تدمد:1734-1922
DOI:10.5114/aoms.2020.97056