دورية أكاديمية
Laboratory markers of adaptation to Arctic conditions: scientific search and prospects of implementation.
| العنوان: | Laboratory markers of adaptation to Arctic conditions: scientific search and prospects of implementation. |
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| عنوان ترانسليتريتد: | Лабораторные маркеры адаптации к условиям Арктики: научный поиск и перспективы внедрения. |
| المؤلفون: | Aleksanin SS; NRCERM, EMERCOM of Russia., Alkhutova NA; NRCERM, EMERCOM of Russia., Zhizhina OL; Saint-Petersburg Medical and Social Institute., Kovyazina NA; NRCERM, EMERCOM of Russia., Nesterenko NV; Department of Medical and Psychological Support, EMERCOM of Russia., Rybnikov VY; NRCERM, EMERCOM of Russia. |
| المصدر: | Klinicheskaia laboratornaia diagnostika [Klin Lab Diagn] 2022 May 21; Vol. 67 (5), pp. 267-270. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Meditsina Country of Publication: Russia (Federation) NLM ID: 9432021 Publication Model: Print Cited Medium: Print ISSN: 0869-2084 (Print) Linking ISSN: 08692084 NLM ISO Abbreviation: Klin Lab Diagn Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Moskva : "Meditsina", 1992- |
| مواضيع طبية MeSH: | Hydrocortisone* , Insulins*, Adaptation, Physiological ; Arctic Regions ; Biomarkers ; Humans |
| مستخلص: | The complex of climatic and geographical conditions of the Arctic determines the high intensity of the polysystem adaptive response of the organism, the duration of which is additionally influenced by individual genetic characteristics, social conditions, psychological and work loads. Taking into account the relevance of timely prevention and early diagnosis of stress-induced somatic pathology in EMERCOM employees working in unfavorable climatic and geographical zones, the authors evaluated the informative value of determining the level of steroid hormones and insulin as laboratory markers of adaptation to Arctic conditions. The expediency of developing objective criteria for the interpretation of the insulin/cortisol index and studying the informativeness of the 17ONprogesterone level as the earliest marker of adaptation to unfavorable climatic and geographical conditions of the Arctic is substantiated. Competing Interests: The authors declare no conflict of interest. |
| References: | Problems of health and social development of the Arctic zone of Russia. Russia’s contribution to the International Polar Year 2007/08 [Problemy zdravookhraneniya i social’nogo razvitiya Arkticheskoy zony Rossii]. Degteva G.N., ed. Мoscow: Paulsen; 2011. ISBN 9785987970492. (in Russian). Gora E.P. Human ecology [Ekologiya cheloveka]. Moscow: Drofa; 2007. (in Russian). Popkova V.A. Analysis of change in the endocrine profile in residents of Arkhangelsk for 20 years. Sovremennye problemy nauki i obrazovaniya. 2019; 6. Available from: https://science-education.ru/ru/article/view?id=29398 (accessed 20 September 2021). (in Russian). Zaichik A.Sh., Churilov L.P. General pathophysiology (with the basics of immunopathology) [Obshchaya patofiziologiya (s osnovami immunopatologii)]. Patofiziologiya. In 3 vol. 4th ed. St.Petersburg: ELBI-SPb; 2008. ISBN 9785939790314. (in Russian). Alkhutova N.A., Kovyazina N.A. The method for assessing the adaptive reserves of the human body. Patent RF № 2679906; 2019. (in Russian). Selyatitskaya V.G. Glucocorticoid hormones from adaptation processes to northern ecology factors up to metabolic disturbances at diabetes. Byulleten’ Sibirskogo otdeleniya RAMN. 2012; 32(1): 13-20. (in Russian). |
| فهرسة مساهمة: | Keywords: 17ON-progesterone; Arctic; DHEAS/cortisol index; adaptation markers; adaptive response; insulin/cortisol index |
| المشرفين على المادة: | 0 (Biomarkers) 0 (Insulins) WI4X0X7BPJ (Hydrocortisone) |
| تواريخ الأحداث: | Date Created: 20220525 Date Completed: 20220527 Latest Revision: 20220527 |
| رمز التحديث: | 20240829 |
| DOI: | 10.51620/0869-2084-2022-67-5-267-270 |
| PMID: | 35613344 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0869-2084 |
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| DOI: | 10.51620/0869-2084-2022-67-5-267-270 |