دورية أكاديمية
أعرض في EDS

Expression Analysis of Genes Involved in Transport Processes in Mice with MPTP-Induced Model of Parkinson's Disease.

التفاصيل البيبلوغرافية
العنوان: Expression Analysis of Genes Involved in Transport Processes in Mice with MPTP-Induced Model of Parkinson's Disease.
المؤلفون: Rudenok MM; Institute of Molecular Genetics of National Research Centre 'Kurchatov Institute', 2 Kurchatova Sq., 123182 Moscow, Russia., Shadrina MI; Institute of Molecular Genetics of National Research Centre 'Kurchatov Institute', 2 Kurchatova Sq., 123182 Moscow, Russia., Filatova EV; Institute of Molecular Genetics of National Research Centre 'Kurchatov Institute', 2 Kurchatova Sq., 123182 Moscow, Russia., Rybolovlev IN; Institute of Molecular Genetics of National Research Centre 'Kurchatov Institute', 2 Kurchatova Sq., 123182 Moscow, Russia., Nesterov MS; Scientific Center of Biomedical Technologies of the Federal Medical and Biological Agency of Russia, Svetlye Gory Village, Post Office Otradnoe, Krasnogorsk District, 143442 Moscow, Russia., Abaimov DA; The Research Centre of Neurology, 80, Volokolamskoye Shosse, 125367 Moscow, Russia., Ageldinov RA; Scientific Center of Biomedical Technologies of the Federal Medical and Biological Agency of Russia, Svetlye Gory Village, Post Office Otradnoe, Krasnogorsk District, 143442 Moscow, Russia., Kolacheva AA; Koltsov Institute of Developmental Biology, Russian Academy of Sciences, 26 Vavilov Street, 119334 Moscow, Russia., Ugrumov MV; Koltsov Institute of Developmental Biology, Russian Academy of Sciences, 26 Vavilov Street, 119334 Moscow, Russia., Slominsky PA; Institute of Molecular Genetics of National Research Centre 'Kurchatov Institute', 2 Kurchatova Sq., 123182 Moscow, Russia., Alieva AK; Institute of Molecular Genetics of National Research Centre 'Kurchatov Institute', 2 Kurchatova Sq., 123182 Moscow, Russia.
المصدر: Life (Basel, Switzerland) [Life (Basel)] 2022 May 19; Vol. 12 (5). Date of Electronic Publication: 2022 May 19.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101580444 Publication Model: Electronic Cited Medium: Print ISSN: 2075-1729 (Print) Linking ISSN: 20751729 NLM ISO Abbreviation: Life (Basel) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI AG, 2011-
مستخلص: Processes of intracellular and extracellular transport play one of the most important roles in the functioning of cells. Changes to transport mechanisms in a neuron can lead to the disruption of many cellular processes and even to cell death. It was shown that disruption of the processes of vesicular, axonal, and synaptic transport can lead to a number of diseases of the central nervous system, including Parkinson's disease (PD). Here, we studied changes in the expression of genes whose protein products are involved in the transport processes ( Snca , Drd2 , Rab5a , Anxa2 , and Nsf ) in the brain tissues and peripheral blood of mice with MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine)-induced models of PD. We detected changes in the expressions of Drd2 , Anxa2 , and Nsf at the earliest modeling stages. Additionally, we have identified conspicuous changes in the expression level of Anxa2 in the striatum and substantia nigra of mice with MPTP-induced models of PD in its early stages. These data clearly suggest the involvement of protein products in these genes in the earliest stages of the pathogenesis of PD.
References: Neurobiol Dis. 2006 Feb;21(2):305-13. (PMID: 16143538)
Cell. 2004 Sep 3;118(5):607-17. (PMID: 15339665)
Annu Rev Cell Dev Biol. 2012;28:279-308. (PMID: 23057743)
Mol Neurobiol. 2021 Jul;58(7):3119-3140. (PMID: 33629273)
Neurology. 2012 Sep 18;79(12):1288-95. (PMID: 22987743)
J Neurobiol. 2004 Feb 5;58(2):164-74. (PMID: 14704949)
Trends Neurosci. 2011 Jun;34(6):326-37. (PMID: 21596448)
Physiol Rev. 1980 Oct;60(4):1167-283. (PMID: 6159657)
Nature. 2016 Nov 09;539(7628):207-216. (PMID: 27830778)
Mol Psychiatry. 2003 Sep;8(9):797-810. (PMID: 12931207)
J Physiol. 1967 Sep;192(2):407-36. (PMID: 4383089)
Drug Alcohol Depend. 1998 Jun-Jul;51(1-2):73-85. (PMID: 9716931)
Neurology. 1996 Mar;46(3):791-5. (PMID: 8618685)
Neurobiol Dis. 2017 Sep;105:321-327. (PMID: 27956085)
PeerJ. 2018 May 09;6:e4719. (PMID: 29761043)
Dev Neurobiol. 2007 Aug;67(9):1183-203. (PMID: 17514710)
Biochim Biophys Acta. 2006 Nov-Dec;1762(11-12):1094-108. (PMID: 16730956)
Mov Disord. 1999 Sep;14(5):764-71. (PMID: 10495037)
Exp Cell Res. 2014 Oct 15;328(1):1-19. (PMID: 25088255)
Restor Neurol Neurosci. 2000;16(2):135-142. (PMID: 12671216)
Dokl Biol Sci. 2014 May;456(1):160-4. (PMID: 24985505)
Mov Disord. 2015 May;30(6):770-9. (PMID: 25900096)
Eur J Pharmacol. 1971 Oct;16(2):176-80. (PMID: 4405780)
Prog Neurobiol. 2003 Aug;70(5):387-407. (PMID: 14511698)
Brain Res. 2005 Jun 7;1046(1-2):195-206. (PMID: 15882845)
Biochem Pharmacol. 2011 Jan 1;81(1):144-56. (PMID: 20858461)
Am J Hum Genet. 2003 Mar;72(3):722-7. (PMID: 12545426)
Neuroscience. 2011 May 5;181:175-88. (PMID: 21382448)
PLoS One. 2014 Dec 08;9(12):e114216. (PMID: 25486126)
Mol Genet Metab Rep. 2020 Apr 06;23:100584. (PMID: 32280590)
Exp Neurol. 2002 Jun;175(2):303-17. (PMID: 12061862)
Mol Biol Cell. 2006 Nov;17(11):4709-19. (PMID: 16914524)
Brain Res. 1991 Jul 12;553(2):275-83. (PMID: 1681983)
Anal Biochem. 2004 Dec 1;335(1):30-41. (PMID: 15519568)
Neuron. 2015 Feb 4;85(3):484-96. (PMID: 25654254)
PLoS One. 2016 Feb 26;11(2):e0149621. (PMID: 26919047)
Curr Neuropharmacol. 2017;15(1):157-165. (PMID: 27568544)
J Neurochem. 2017 Nov;143(4):409-417. (PMID: 28267200)
Ergeb Physiol. 1961;51:299-430. (PMID: 13889060)
Am J Med Genet B Neuropsychiatr Genet. 2003 Jan 1;116B(1):103-25. (PMID: 12497624)
Parkinsonism Relat Disord. 2008;14 Suppl 2:S112-5. (PMID: 18585085)
Mol Neurobiol. 2018 Sep;55(9):7229-7241. (PMID: 29397556)
Hum Mol Genet. 2014 Sep 1;23(17):4621-38. (PMID: 24740878)
J Parkinsons Dis. 2014;4(1):77-87. (PMID: 24366928)
Curr Biol. 1998 Mar 12;8(6):R199-201. (PMID: 9606091)
Neurobiol Dis. 2018 Jan;109(Pt B):219-225. (PMID: 28323023)
Int Rev Cell Mol Biol. 2012;299:27-115. (PMID: 22959301)
Brain Res. 2002 Oct 11;952(1):122-7. (PMID: 12363411)
ACS Chem Neurosci. 2010 Jan 8;1(4):306-314. (PMID: 20495672)
J Neural Transm (Vienna). 2011 May;118(5):727-35. (PMID: 21533607)
Mol Autism. 2018 Nov 6;9:56. (PMID: 30443311)
Elife. 2016 Jan 29;5:. (PMID: 26824392)
Science. 1989 Jan 20;243(4889):398-400. (PMID: 2563176)
Neurosci Lett. 2006 Apr 3;396(3):187-91. (PMID: 16386370)
Annu Rev Neurosci. 2000;23:39-71. (PMID: 10845058)
Annu Rev Cell Dev Biol. 1999;15:733-98. (PMID: 10611977)
Mol Neurobiol. 2013 Apr;47(2):460-5. (PMID: 23180276)
Brain Pathol. 2009 Jan;19(1):91-107. (PMID: 18462474)
Int Rev Cytol. 2001;207:71-112. (PMID: 11352269)
Lancet. 2015 Aug 29;386(9996):896-912. (PMID: 25904081)
J Biol Chem. 2000 Jun 30;275(26):20179-87. (PMID: 10770933)
World J Gastroenterol. 2016 Jul 7;22(25):5742-52. (PMID: 27433087)
Mov Disord. 2011 Jul;26(8):1386-97. (PMID: 21538530)
Exp Physiol. 2013 Jan;98(1):233-44. (PMID: 22636255)
J Parkinsons Dis. 2015;5(4):749-63. (PMID: 26577653)
Curr Opin Neurobiol. 2014 Aug;27:165-70. (PMID: 24762653)
Exp Neurol. 2014 Nov;261:206-16. (PMID: 24907399)
Hum Mol Genet. 2017 Aug 1;26(15):2933-2948. (PMID: 28482024)
Science. 2010 Sep 24;329(5999):1663-7. (PMID: 20798282)
Hum Mol Genet. 2017 May 1;26(9):1656-1669. (PMID: 28334751)
J Biol Chem. 2001 Feb 16;276(7):5310-5. (PMID: 11067857)
J Pharmacol Exp Ther. 1976 Nov;199(2):336-52. (PMID: 185360)
J Neural Transm (Vienna). 1996;103(8-9):987-1041. (PMID: 9013391)
Mol Neurobiol. 2017 Nov;54(9):6775-6784. (PMID: 27757834)
Neurosci Lett. 2011 Jun 8;496(3):157-62. (PMID: 21514359)
Arch Neurol. 2005 Jun;62(6):917-21. (PMID: 15956162)
Genome Med. 2014 Jun 30;6(6):48. (PMID: 25061481)
J Biol Chem. 2001 May 4;276(18):15249-55. (PMID: 11278971)
Physiol Genomics. 2000 Apr 27;2(3):143-7. (PMID: 11015593)
Science. 1983 Feb 25;219(4587):979-80. (PMID: 6823561)
Int J Mol Sci. 2013 Mar 19;14(3):6259-305. (PMID: 23519104)
Curr Opin Neurobiol. 2000 Jun;10(3):293-302. (PMID: 10851178)
Am J Pathol. 2007 Mar;170(3):951-66. (PMID: 17322380)
Brain Pathol. 2017 Jan;27(1):3-12. (PMID: 26667592)
Biochem Soc Trans. 2011 Oct;39(5):1211-5. (PMID: 21936791)
Annu Rev Biochem. 1978;47:933-65. (PMID: 150255)
Semin Thromb Hemost. 2013 Jun;39(4):338-46. (PMID: 23483454)
Curr Neurol Neurosci Rep. 2013 Jul;13(7):362. (PMID: 23690026)
Neurol Res. 2009 Sep;31(7):687-91. (PMID: 19061540)
Bioessays. 2002 Apr;24(4):308-18. (PMID: 11948617)
Prog Neurobiol. 2001 Oct;65(2):135-72. (PMID: 11403877)
Physiol Res. 2019 Mar 6;68(1):17-24. (PMID: 30433804)
J Neurophysiol. 2010 Dec;104(6):3009-20. (PMID: 20926611)
Neurodegeneration. 1996 Dec;5(4):299-312. (PMID: 9117541)
J Neurol Sci. 1973 Dec;20(4):415-55. (PMID: 4272516)
Biol Psychiatry. 1996 Jan 15;39(2):82-91. (PMID: 8717605)
Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):15918-23. (PMID: 23019375)
J Neurosci. 2007 Oct 3;27(40):10685-94. (PMID: 17913902)
Biochem Biophys Res Commun. 2011 Feb 11;405(2):192-6. (PMID: 21216236)
Mol Neurodegener. 2009 Nov 23;4:48. (PMID: 19930651)
معلومات مُعتمدة: 20-15-00262 Russian Science Foundation; 2022 № 0088-2021-0018 the IDB RAS Government basic research program; 075-15-2021-135 the Ministry of Science and Higher Education of the Russian Federation
فهرسة مساهمة: Keywords: MPTP; Parkinson’s disease; early diagnostics; gene expression; molecular mechanisms; neurodegeneration; neurological diseases; transport processes
تواريخ الأحداث: Date Created: 20220528 Latest Revision: 20220716
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC9146539
DOI: 10.3390/life12050751
PMID: 35629417
قاعدة البيانات: MEDLINE
الوصف
تدمد:2075-1729
DOI:10.3390/life12050751