دورية أكاديمية
Pentazocine with rectal diclofenac versus pentazocine alone for pain relief following caesarean delivery in Enugu, Nigeria: A randomized controlled trial.
العنوان: | Pentazocine with rectal diclofenac versus pentazocine alone for pain relief following caesarean delivery in Enugu, Nigeria: A randomized controlled trial. |
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المؤلفون: | Ofor IJ; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology - Teaching Hospital, Parklane, Enugu, Nigeria., Enebe JT; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology - Teaching Hospital, Parklane, Enugu, Nigeria.; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology, College of Medicine, Government Residential Area, Parklane, Enugu, Nigeria., Ofor NE; Departments of Paediatrics, University of Nigeria Teaching Hospital (UNTH), Ituku-Ozalla, Enugu, Nigeria., Onyia CN; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology, College of Medicine, Government Residential Area, Parklane, Enugu, Nigeria., Omeke CA; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology - Teaching Hospital, Parklane, Enugu, Nigeria., Nevo CO; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology - Teaching Hospital, Parklane, Enugu, Nigeria., Enyinna PC; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology - Teaching Hospital, Parklane, Enugu, Nigeria., Awkadigwe FI; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology - Teaching Hospital, Parklane, Enugu, Nigeria., Eleje GU; Effective Care Research Unit, Departments of Obstetrics and Gynaecology, Faculty of Medicine, Nnamdi Azikiwe University, Nnewi Campus, Nigeria., Ezugwu FO; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology, College of Medicine, Government Residential Area, Parklane, Enugu, Nigeria. |
المصدر: | The Journal of international medical research [J Int Med Res] 2022 May; Vol. 50 (5), pp. 3000605221102092. |
نوع المنشور: | Journal Article; Randomized Controlled Trial |
اللغة: | English |
بيانات الدورية: | Publisher: Sage Publications Country of Publication: England NLM ID: 0346411 Publication Model: Print Cited Medium: Internet ISSN: 1473-2300 (Electronic) Linking ISSN: 03000605 NLM ISO Abbreviation: J Int Med Res Subsets: MEDLINE |
أسماء مطبوعة: | Publication: Nov. 2012- : London : Sage Publications Original Publication: Northampton, Eng., Cambridge Medical Publications ltd. |
مواضيع طبية MeSH: | Diclofenac*/therapeutic use , Pentazocine*/therapeutic use, Analgesics, Opioid/therapeutic use ; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use ; Cesarean Section/adverse effects ; Female ; Humans ; Nigeria ; Pain, Postoperative/drug therapy ; Pain, Postoperative/etiology ; Pregnancy ; Single-Blind Method |
مستخلص: | Objective: To measure postoperative pain relief following the use of rectal diclofenac combined with intramuscular pentazocine compared with intramuscular pentazocine alone in patients undergoing a caesarean delivery. Methods: This single-blind randomized controlled trial enrolled pregnant women that had a caesarean section at the Enugu State University of Science and Technology Teaching Hospital, Enugu, Nigeria. Study participants were randomized to receive either 100 mg of rectal diclofenac given every 12 h plus 30 mg of intramuscular pentazocine given every 6 h (group A) or 60 mg of intramuscular pentazocine given every 6 h (group B). The primary outcome was the level of pain as measured using a visual analogue scale. The secondary outcomes were the level of satisfaction with pain relief and need for rescue analgesia. Results: A total of 200 participants were randomized equally into the two groups. Participants in group A had significantly better pain control and satisfaction over the 48 h after surgery compared with group B. Significantly more of group B required rescue analgesia for breakthrough pain compared with group A. Conclusion: Rectal diclofenac combined with intramuscular pentazocine was significantly better at controlling pain compared with pentazocine alone in the first 48 h following caesarean section. Trial registration number: PACTR202107706925314 at www.pactr.org on 28 July 2021. |
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فهرسة مساهمة: | Keywords: Analgesia; Enugu; caesarean delivery; pentazocine; rectal diclofenac |
المشرفين على المادة: | 0 (Analgesics, Opioid) 0 (Anti-Inflammatory Agents, Non-Steroidal) 144O8QL0L1 (Diclofenac) RP4A60D26L (Pentazocine) |
تواريخ الأحداث: | Date Created: 20220531 Date Completed: 20220602 Latest Revision: 20220716 |
رمز التحديث: | 20240628 |
مُعرف محوري في PubMed: | PMC9160910 |
DOI: | 10.1177/03000605221102092 |
PMID: | 35638533 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1473-2300 |
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DOI: | 10.1177/03000605221102092 |