دورية أكاديمية
أعرض في EDS

Pentazocine with rectal diclofenac versus pentazocine alone for pain relief following caesarean delivery in Enugu, Nigeria: A randomized controlled trial.

التفاصيل البيبلوغرافية
العنوان: Pentazocine with rectal diclofenac versus pentazocine alone for pain relief following caesarean delivery in Enugu, Nigeria: A randomized controlled trial.
المؤلفون: Ofor IJ; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology - Teaching Hospital, Parklane, Enugu, Nigeria., Enebe JT; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology - Teaching Hospital, Parklane, Enugu, Nigeria.; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology, College of Medicine, Government Residential Area, Parklane, Enugu, Nigeria., Ofor NE; Departments of Paediatrics, University of Nigeria Teaching Hospital (UNTH), Ituku-Ozalla, Enugu, Nigeria., Onyia CN; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology, College of Medicine, Government Residential Area, Parklane, Enugu, Nigeria., Omeke CA; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology - Teaching Hospital, Parklane, Enugu, Nigeria., Nevo CO; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology - Teaching Hospital, Parklane, Enugu, Nigeria., Enyinna PC; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology - Teaching Hospital, Parklane, Enugu, Nigeria., Awkadigwe FI; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology - Teaching Hospital, Parklane, Enugu, Nigeria., Eleje GU; Effective Care Research Unit, Departments of Obstetrics and Gynaecology, Faculty of Medicine, Nnamdi Azikiwe University, Nnewi Campus, Nigeria., Ezugwu FO; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology, College of Medicine, Government Residential Area, Parklane, Enugu, Nigeria.
المصدر: The Journal of international medical research [J Int Med Res] 2022 May; Vol. 50 (5), pp. 3000605221102092.
نوع المنشور: Journal Article; Randomized Controlled Trial
اللغة: English
بيانات الدورية: Publisher: Sage Publications Country of Publication: England NLM ID: 0346411 Publication Model: Print Cited Medium: Internet ISSN: 1473-2300 (Electronic) Linking ISSN: 03000605 NLM ISO Abbreviation: J Int Med Res Subsets: MEDLINE
أسماء مطبوعة: Publication: Nov. 2012- : London : Sage Publications
Original Publication: Northampton, Eng., Cambridge Medical Publications ltd.
مواضيع طبية MeSH: Diclofenac*/therapeutic use , Pentazocine*/therapeutic use, Analgesics, Opioid/therapeutic use ; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use ; Cesarean Section/adverse effects ; Female ; Humans ; Nigeria ; Pain, Postoperative/drug therapy ; Pain, Postoperative/etiology ; Pregnancy ; Single-Blind Method
مستخلص: Objective: To measure postoperative pain relief following the use of rectal diclofenac combined with intramuscular pentazocine compared with intramuscular pentazocine alone in patients undergoing a caesarean delivery.
Methods: This single-blind randomized controlled trial enrolled pregnant women that had a caesarean section at the Enugu State University of Science and Technology Teaching Hospital, Enugu, Nigeria. Study participants were randomized to receive either 100 mg of rectal diclofenac given every 12 h plus 30 mg of intramuscular pentazocine given every 6 h (group A) or 60 mg of intramuscular pentazocine given every 6 h (group B). The primary outcome was the level of pain as measured using a visual analogue scale. The secondary outcomes were the level of satisfaction with pain relief and need for rescue analgesia.
Results: A total of 200 participants were randomized equally into the two groups. Participants in group A had significantly better pain control and satisfaction over the 48 h after surgery compared with group B. Significantly more of group B required rescue analgesia for breakthrough pain compared with group A.
Conclusion: Rectal diclofenac combined with intramuscular pentazocine was significantly better at controlling pain compared with pentazocine alone in the first 48 h following caesarean section. Trial registration number: PACTR202107706925314 at www.pactr.org on 28 July 2021.
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فهرسة مساهمة: Keywords: Analgesia; Enugu; caesarean delivery; pentazocine; rectal diclofenac
المشرفين على المادة: 0 (Analgesics, Opioid)
0 (Anti-Inflammatory Agents, Non-Steroidal)
144O8QL0L1 (Diclofenac)
RP4A60D26L (Pentazocine)
تواريخ الأحداث: Date Created: 20220531 Date Completed: 20220602 Latest Revision: 20220716
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC9160910
DOI: 10.1177/03000605221102092
PMID: 35638533
قاعدة البيانات: MEDLINE
الوصف
تدمد:1473-2300
DOI:10.1177/03000605221102092