دورية أكاديمية
Clinical effectiveness of a pneumatic compression device combined with low-molecular-weight heparin for the prevention of deep vein thrombosis in trauma patients: A single-center retrospective cohort study.
| العنوان: | Clinical effectiveness of a pneumatic compression device combined with low-molecular-weight heparin for the prevention of deep vein thrombosis in trauma patients: A single-center retrospective cohort study. |
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| المؤلفون: | Guo PC; Emergency Department, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China., Li N; Plastic Surgery Department, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China., Zhong HM; Emergency Department, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China., Zhao GF; Emergency Department, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China. |
| المصدر: | World journal of emergency medicine [World J Emerg Med] 2022; Vol. 13 (3), pp. 189-195. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: World Journal of Emergency Medicine Press Country of Publication: China NLM ID: 101549691 Publication Model: Print Cited Medium: Print ISSN: 1920-8642 (Print) Linking ISSN: 19208642 NLM ISO Abbreviation: World J Emerg Med Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: [Hangzhou] : World Journal of Emergency Medicine Press |
| مستخلص: | Background: To investigate the clinical effectiveness of a pneumatic compression device (PCD) combined with low-molecular-weight heparin (LMWH) for the prevention and treatment of deep vein thrombosis (DVT) in trauma patients. Methods: This study retrospectively analyzed 286 patients with mild craniocerebral injury and clavicular fractures admitted to our department from January 2016 to February 2020. Patients treated with only LMWH served as the control group, and patients treated with a PCD combined with LMWH as the observation group. The incidence of DVT, postoperative changes in the visual analogue scale (VAS) score, and coagulation function were observed and compared between the two groups. Excluding the influence of other single factors, binary logistic regression analysis was used to evaluate the use of a PCD in the patient's postoperative coagulation function. Results: After excluding 34 patients who did not meet the inclusion criteria, 252 patients were were included. The incidence of DVT in the observation group was significantly lower than that in the control group (5.6% vs. 15.1%, χ 2 =4.605, P <0.05). The postoperative VAS scores of the two groups were lower than those before surgery ( P <0.05). The coagulation function of the observation group was significantly higher than that of the control group, with a better combined anticoagulant effect ( P <0.05). There were no significant differences between the two groups in preoperative or postoperative Glasgow Coma Scale scores, intraoperative blood loss, postoperative infection rate, or length of hospital stay ( P >0.05). According to logistic regression analysis, the postoperative risk of DVT in patients who received LMWH alone was 1.764 times that of patients who received LMWH+PCD ( P <0.05). The area under the receiver operating characteristic (AUROC) curve of partial thromboplastin time (APTT) and platelet (PLT) were greater than 0.5, indicating that they were the influence indicators of adding PCD to prevent DVT. Excluding the influence of other variables, LMWH+PCD effectively improved the coagulation function of patients. Conclusions: Compared with LMWH alone, LMWH+PCD could improve blood rheology and coagulation function in patients with traumatic brain injury and clavicular fracture, reduce the incidence of DVT, shorten the length of hospital stay, and improve the clinical effectiveness of treatment. Competing Interests: Conflicts of interest: No benefits in any form have been received or will be received from a commercial party related directly or indirectly to the subject of this article. (Copyright: © World Journal of Emergency Medicine.) |
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| فهرسة مساهمة: | Keywords: Deep vein thrombosis; Logistic regression analysis; Low-molecular-weight heparin; Pneumatic compression device; Trauma |
| تواريخ الأحداث: | Date Created: 20220601 Latest Revision: 20220716 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC9108905 |
| DOI: | 10.5847/wjem.j.1920-8642.2022.040 |
| PMID: | 35646216 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1920-8642 |
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| DOI: | 10.5847/wjem.j.1920-8642.2022.040 |