دورية أكاديمية
Synthesis of Optically Active Helical Polycarbenes through Helix-Sense-Selective Polymerization Strategy and Their Application in Chiral Separation.
| العنوان: | Synthesis of Optically Active Helical Polycarbenes through Helix-Sense-Selective Polymerization Strategy and Their Application in Chiral Separation. |
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| المؤلفون: | Gao BR; Department of Polymer Science and Engineering, School of Chemistry and Chemical Engineering, and Anhui Province Key Laboratory of Advanced Catalytic Materials and Reaction Engineering, Hefei University of Technology, 193 Tunxi Road, Hefei 230009, Anhui Province, China., Wu YJ; Department of Polymer Science and Engineering, School of Chemistry and Chemical Engineering, and Anhui Province Key Laboratory of Advanced Catalytic Materials and Reaction Engineering, Hefei University of Technology, 193 Tunxi Road, Hefei 230009, Anhui Province, China., Xu L; Department of Polymer Science and Engineering, School of Chemistry and Chemical Engineering, and Anhui Province Key Laboratory of Advanced Catalytic Materials and Reaction Engineering, Hefei University of Technology, 193 Tunxi Road, Hefei 230009, Anhui Province, China., Zou H; Department of Polymer Science and Engineering, School of Chemistry and Chemical Engineering, and Anhui Province Key Laboratory of Advanced Catalytic Materials and Reaction Engineering, Hefei University of Technology, 193 Tunxi Road, Hefei 230009, Anhui Province, China., Zhou L; Department of Polymer Science and Engineering, School of Chemistry and Chemical Engineering, and Anhui Province Key Laboratory of Advanced Catalytic Materials and Reaction Engineering, Hefei University of Technology, 193 Tunxi Road, Hefei 230009, Anhui Province, China., Liu N; Department of Polymer Science and Engineering, School of Chemistry and Chemical Engineering, and Anhui Province Key Laboratory of Advanced Catalytic Materials and Reaction Engineering, Hefei University of Technology, 193 Tunxi Road, Hefei 230009, Anhui Province, China., Wu ZQ; Department of Polymer Science and Engineering, School of Chemistry and Chemical Engineering, and Anhui Province Key Laboratory of Advanced Catalytic Materials and Reaction Engineering, Hefei University of Technology, 193 Tunxi Road, Hefei 230009, Anhui Province, China.; State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, China. |
| المصدر: | ACS macro letters [ACS Macro Lett] 2022 Jun 21; Vol. 11 (6), pp. 785-791. Date of Electronic Publication: 2022 Jun 02. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 101574672 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2161-1653 (Electronic) Linking ISSN: 21611653 NLM ISO Abbreviation: ACS Macro Lett Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Washington, D.C. : American Chemical Society, [2012]- |
| مواضيع طبية MeSH: | Polymers*/chemistry, Ligands ; Molecular Conformation ; Polymerization ; Stereoisomerism |
| مستخلص: | In this work, helical polycarbenes with optical activity were designed and facilely synthesized through the helix-sense-selective polymerization (HSSP) of the diazoacetate monomer with a dimethylbenzyl ester pendant catalyzed by π-allylPdCl with chiral phosphine ligands at room temperature. The polymerization was carried out in a living and controlled style, and a range of helical polycarbenes with the desired number-average molecular weights and narrow molecular weight distributions were obtained. Circular dichroism and UV-vis analyses revealed that these polycarbenes exhibited a stable helical conformation with a preferred handedness, and their helical directions were dependent on the chirality of the chiral phosphine ligands. Further studies showed that the helical conformation of the obtained polycarbenes was from the polymeric backbone rather than the intermolecular aggregation in the solutions. Moreover, the prepared, optically active, helical polycarbenes possessed excellent enantioselective crystallization ability for threonine racemates. The enantiomeric excess (e.e.) of the induced crystals could be up to 83% via utilizing the prepared helical polycarbenes as a chiral separation agent. |
| المشرفين على المادة: | 0 (Ligands) 0 (Polymers) |
| تواريخ الأحداث: | Date Created: 20220602 Date Completed: 20220622 Latest Revision: 20220623 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1021/acsmacrolett.2c00212 |
| PMID: | 35653295 |
| قاعدة البيانات: | MEDLINE |
Find this issue from the American Chemical Society | تدمد: | 2161-1653 |
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| DOI: | 10.1021/acsmacrolett.2c00212 |