دورية أكاديمية
Amoebae: Hiding in Plain Sight: Unappreciated Hosts for the Very Large Viruses.
| العنوان: | Amoebae: Hiding in Plain Sight: Unappreciated Hosts for the Very Large Viruses. |
|---|---|
| المؤلفون: | Queiroz VF; Laboratório de Vírus, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; email: jonatas.abrahao@gmail.com., Rodrigues RAL; Laboratório de Vírus, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; email: jonatas.abrahao@gmail.com., de Miranda Boratto PV; Laboratório de Vírus, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; email: jonatas.abrahao@gmail.com., La Scola B; Department of Microbes, Evolution, Phylogeny and Infection, Institut de Recherche pour le Développement, Assistance Publique-Hôpitaux de Marseille, Aix-Marseille Université, Marseille, France; email: bernard.la-scola@univ-amu.fr.; Institut Hospitalo-Universitaire Méditerranée Infection, Marseille, France., Andreani J; Department of Microbes, Evolution, Phylogeny and Infection, Institut de Recherche pour le Développement, Assistance Publique-Hôpitaux de Marseille, Aix-Marseille Université, Marseille, France; email: bernard.la-scola@univ-amu.fr.; Institut Hospitalo-Universitaire Méditerranée Infection, Marseille, France.; Laboratoire de Virologie, Centre Hospitalier Universitaire Grenoble-Alpes, Grenoble, France., Abrahão JS; Laboratório de Vírus, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; email: jonatas.abrahao@gmail.com. |
| المصدر: | Annual review of virology [Annu Rev Virol] 2022 Sep 29; Vol. 9 (1), pp. 79-98. Date of Electronic Publication: 2022 Jun 02. |
| نوع المنشور: | Journal Article; Review; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Annual Reviews Country of Publication: United States NLM ID: 101625721 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2327-0578 (Electronic) Linking ISSN: 2327056X NLM ISO Abbreviation: Annu Rev Virol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Palo Alto, California : Annual Reviews, 2014- |
| مواضيع طبية MeSH: | Amoeba* , Giant Viruses*/genetics , Viruses*/genetics, DNA Viruses/genetics ; Genome, Viral ; Humans ; Metagenomics ; Phylogeny |
| مستخلص: | For decades, viruses have been isolated primarily from humans and other organisms. Interestingly, one of the most complex sides of the virosphere was discovered using free-living amoebae as hosts. The discovery of giant viruses in the early twenty-first century opened a new chapter in the field of virology. Giant viruses are included in the phylum Nucleocytoviricota and harbor large and complex DNA genomes (up to 2.7 Mb) encoding genes never before seen in the virosphere and presenting gigantic particles (up to 1.5 μm). Different amoebae have been used to isolate and characterize a plethora of new viruses with exciting details about novel viral biology. Through distinct isolation techniques and metagenomics, the diversity and complexity of giant viruses have astonished the scientific community. Here, we discuss the latest findings on amoeba viruses and how using these single-celled organisms as hosts has revealed entities that have remained hidden in plain sight for ages. |
| فهرسة مساهمة: | Keywords: NCLDV; Nucleocytoviricota; amoebae; genome complexity; giant virus; viral diversity |
| تواريخ الأحداث: | Date Created: 20220602 Date Completed: 20221003 Latest Revision: 20221222 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1146/annurev-virology-100520-125832 |
| PMID: | 35655338 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 2327-0578 |
|---|---|
| DOI: | 10.1146/annurev-virology-100520-125832 |