دورية أكاديمية
Temporal trends in intraventricular hemorrhage in preterm infants: A Brazilian multicenter cohort.
| العنوان: | Temporal trends in intraventricular hemorrhage in preterm infants: A Brazilian multicenter cohort. |
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| المؤلفون: | de Figueiredo Vinagre LE; Womens' Hospital, State University of Campinas, Unicamp 101, Alexander Fleming St, Barao Geraldo, Campinas, Sao Paulo, Brazil 13083-881. Electronic address: bovinagre@uol.com.br., de Siqueira Caldas JP; Departament of Pediatrics, School of Medical Sciences, State University of Campinas - Unicamp, 60, Vital Brasil, St. Cidade Universitaria Zeferino Vaz, Campinas, Sao Paulo, Brazil 13083-888. Electronic address: jamil_pedro@uol.com.br., Martins Marba ST; Departament of Pediatrics, School of Medical Sciences, State University of Campinas - Unicamp, 60, Vital Brasil, St. Cidade Universitaria Zeferino Vaz, Campinas, Sao Paulo, Brazil 13083-888. Electronic address: sergiomarba@gmail.com., Procianoy RS; Department of Pediatrics, School of Medicine, Universidade Federal do Rio Grande do Sul, 2350, Ramiro Barcelos St. - Santa Cecília, Porto Alegre, Rio Grande do Sul, 90035-903, Brazil. Electronic address: rprocianoy@hcpa.edu.br., de Cássia Silveira R; Department of Pediatrics, School of Medicine, Universidade Federal do Rio Grande do Sul, 2350, Ramiro Barcelos St. - Santa Cecília, Porto Alegre, Rio Grande do Sul, 90035-903, Brazil. Electronic address: drarita.c.s@gmail.com., Santiago Rego MA; Department of Pediatrics, Faculty of Medicine, Federal University of Minas Gerais, 190, Prof. Alfredo Balena, Av. - Santa Efigenia, Belo Horizonte, Minas Gerais, 30130-100, Brazil. Electronic address: albertinarego@gmail.com., de Lima Mota Ferreira DM; Departament of Pediatrics, Universidade Federal de Uberlandia, 1720, Para Av, sector 2U - Umuarama, Uberlandia, Minas Gerais, 38400-902, Brazil. Electronic address: daniela.marques@ufu.com.br., Sales Alves Junior JM; Departament of Pediatrics, Faculdade de Ciencias Medicas de Minas Gerais, 275, Ezequiel Dias St, - Centro, Belo Horizonte, Minas Gerais, 30130-110, Brazil. Electronic address: mariano.corumi@gmail.com., Dos Santos JPF; Neonatal Intensive Care Unit, Hospital Estadual de Sumare Dr. Leandro Francheschini, 2400, Amizade Av. - Jardim Bela Vista, Sumare, Sao Paulo, CEP 13175-490, Brazil. Electronic address: jupferraz@gmail.com., Gimenes CB; Neonatal Intensive Care Unit, Hospital Geral de Pirajussara, 1214, Ibirama av. - Jardim Sao Judas Tadeu, Taboao da Serra, São Paulo, 06785-300, Brazil. Electronic address: carolboschi@hotmail.com., de Mello E Silva NM; Neonatal Intensive Care Unit, Hospital Estadual de Diadema, 1641, Jose Bonifacio St. - Serraria, Diadema, São Paulo, 09960-120, Brazil. Electronic address: nathaliamelloesilva@yahoo.com.br., Conde Gonzalez MR; Department of Pediatrics, Hospital Universitario, Universidade Estadual de Londrina, Rodovia Celso Garcia Cid, PR-445, Km 380 - Campus Universitario, Londrina, Parana, 86057-970, Brazil. Electronic address: mrafaelacg@uol.com.br., da Silva RPGVC; Department of Pediatrics, Hospital de Clinicas, Universidade Federal do Paraná, 1299, XV de Novembro st, - Centro, Curitiba, Parana, 80060-000, Brazil. Electronic address: reginavieiracavalcante@gmail.com., do Amaral Gomez DBC; Neonatal Intensive Care Unit, Instituto de Medicina Integral Professor Fernando Figueira - lMIP, 300, Coelhos St, - Boa Vista, Recife, Pernambuco, 50070-550, Brazil. Electronic address: barcala.dafne@gmail.com., do Vale MS; Hospital Universitario da Universidade Federal do Maranhao, 227, Barao de Itapari St, - Centro, Sao Luís, Maranhao, 65020-070, Brazil. Electronic address: maryneavale@gmail.com., de Souza Rugolo LMS; Departament of Pediatrics, Faculdade de Medicina de Botucatu da Universidade Estadual Paulista Julio de Mesquita Filho, Professor Mário Rubens Guimarães Montenegro St, UNESP Campus de Botucatu, Botucatu, Sao Paulo, 18618-687, Brazil. Electronic address: ligia.rugolo@unesp.br., Meneguel Ogata JF; Division of Neonatal Medicine, Department of Pediatrics at Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo. 740, Botucatu St. - Vila Clementino, Sao Paulo, São Paulo, 04023-062, Brazil. Electronic address: joice.meneguel@unifesp.br., de Albuquerque Diniz EM; Division of Neonatology, University of São Paulo, Hospital Universitário, 2565, Prof. Lineu Prestes Av. Butanta, Sao Paulo, Sao Paulo, 05508-000, Brazil. Electronic address: edna.diniz@hc.fm.usp.br., Luz JH; Department of Pediatrics, Hospital São Lucas, Faculdade de Medicina da Pontifícia Universidade Catolica do Rio Grande do Sul, 6690, Ipiranga Av. - Jardim Botânico, Porto Alegre, Rio Grande do Sul, 90619-900, Brazil. Electronic address: jorgeluz@terra.com.br., de Almeida JHCL; Division of Neonatology, Instituto Nacional de Saude da Criança, Mulher e Adolescente Fernandes Figueira, Fundacao Oswaldo Cruz, Rio de Janeiro, Brazil. 716, Rui Barbosa Av., - Flamengo, Rio de Janeiro, Rio de Janeiro, 22250020, Brazil. Electronic address: jhcleme@gmail.com., de Souza MPA; Neonatal Division, Hospital Pedro Ernesto, Universidade Estadual do Rio de Janeiro, 77, 28 de Setembro Blvd, - Vila Isabel, Rio de Janeiro, Rio de Janeiro, 20551-030, Brazil. Electronic address: mrcalvesdesouza@gmail.com., Goncalves Ferri WA; Department of Pediatrics, Faculdade de Medicina de Ribeirão Preto, University of São Paulo. 3900, Bandeirantes Av. - Campus da USP, Ribeirao Preto, São Paulo, 14049-900, Brazil. Electronic address: walusa@fmrp.usp.br. |
| المصدر: | European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society [Eur J Paediatr Neurol] 2022 Jul; Vol. 39, pp. 65-73. Date of Electronic Publication: 2022 May 23. |
| نوع المنشور: | Journal Article; Multicenter Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: Saunders Country of Publication: England NLM ID: 9715169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2130 (Electronic) Linking ISSN: 10903798 NLM ISO Abbreviation: Eur J Paediatr Neurol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: London ; Philadelphia : Saunders, c1997- |
| مواضيع طبية MeSH: | Infant, Premature* , Infant, Premature, Diseases*/epidemiology, Brazil/epidemiology ; Cerebral Hemorrhage/epidemiology ; Cerebral Hemorrhage/etiology ; Cohort Studies ; Female ; Gestational Age ; Humans ; Infant ; Infant, Newborn ; Pregnancy ; Prospective Studies |
| مستخلص: | Background: Intraventricular hemorrhage (IVH) is a serious problem in preterm infants. Brazilian national data are unknown. Objective: To evaluate the incidence and temporal trend of IVH in very low birth weight (VLBW) preterm infants of 18 centers of the Brazilian Network on Neonatal Research. Study Design: National prospective multicenter cohort study including inborn VLBW preterm infants aged 23 0/7 - 33 6/7 weeks' gestation, admitted between 2013 and 2018. The center with the mean incidence rate was used as reference. We applied two adjustments models using perinatal variables, and perinatal + neonatal diseases. Results: Of 6,420 infants, 1951/30.4% (range 27.1-33.8%) had IVH and the disease showed a significant trend towards an overall increase in incidence over time (p = 0.003), especially in three centers. Severe IVH (grade III or IV) occurred in 32.2% (range 29.2-34.5%) of those affected by IVH, with a stable incidence. After adjustments for perinatal variables, the differences persisted among centers: for global IVH, 7 centers had significantly lower rates (OR ranging from 0.31 to 0.62), and 2 presented rates higher than the reference center (OR ranging from 2.00 to 12.46) for severe HIV. Considering perinatal and neonatal variables, 6 centers had significantly lower rates (OR ranging from 0.36 to 0.60) for global IVH than the reference center and 3 had statistically higher rates (OR 1.72, 1.86 and 11.78) for severe forms. Conclusion: The incidence rate of IVH in this Brazilian cohort was high and it revealed an increasing trend towards over time. The severe IVH rate was also worrisome. (© 2022 Published by Elsevier Ltd on behalf of European Paediatric Neurology Society.) |
| فهرسة مساهمة: | Keywords: Corticosteroids; Intraventricular hemorrhage; Multicenter study; Outcome assessments; Premature infant |
| تواريخ الأحداث: | Date Created: 20220613 Date Completed: 20220719 Latest Revision: 20220719 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1016/j.ejpn.2022.05.003 |
| PMID: | 35696888 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1532-2130 |
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| DOI: | 10.1016/j.ejpn.2022.05.003 |