تقرير
A case series of mucormycosis after covid infection in two hospitals.
| العنوان: | A case series of mucormycosis after covid infection in two hospitals. |
|---|---|
| المؤلفون: | Martins HDD; Post Graduation Program in Dentistry, Universidade Federal da Paraíba (UFPB), Campus I - Cidade Universitária, João Pessoa, Paraíba 58033-455, Brazil. Electronic address: helderdomiciano@hotmail.com., Pares AR; Universidad Autónoma de Nuevo León, Mexico., Martínez AT; Oral and Maxillofacial Surgeon, Benemérita Universidad Autonoma de Puebla, Mexico., Guevara RAP; Oral and Maxillofacial Surgeon, School of Dentistry, Torreon Unit, Universidad Autonoma de Coahuila, Mexico., Inaoka SD; Oral and Maxillofacial Surgeon, Hospital Universitário Lauro Wanderley, Universidade Federal da Paraíba, João Pessoa, Paraíba, Brazil., Costa DFN; Oral and Maxillofacial Surgeon, Hospital Universitário Lauro Wanderley, Universidade Federal da Paraíba, João Pessoa, Paraíba, Brazil., Leal CB; Oral and Maxillofacial Surgeon, Hospital Universitário Lauro Wanderley, Universidade Federal da Paraíba, João Pessoa, Paraíba, Brazil., Soares CD; Immunohistochemistry and Histopathology Group / International Research Group, Natal, Brazil., da Paz AR; Pathological Anatomy Service, Hospital Universitário Lauro Wanderley, Universidade Federal da Paraíba, João Pessoa, Paraíba, Brazil., Perez DEDC; Department of Clinical and Preventive Dentistry, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil., Pedraza RM; Universidad Autónoma de Nuevo León, Mexico., Bonan PRF; Post Graduation Program in Dentistry, Universidade Federal da Paraíba (UFPB), Campus I - Cidade Universitária, João Pessoa, Paraíba 58033-455, Brazil. |
| المصدر: | Journal of stomatology, oral and maxillofacial surgery [J Stomatol Oral Maxillofac Surg] 2022 Nov; Vol. 123 (6), pp. e757-e759. Date of Electronic Publication: 2022 Jun 11. |
| نوع المنشور: | Case Reports |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Masson SAS Country of Publication: France NLM ID: 101701089 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2468-7855 (Electronic) Linking ISSN: 24687855 NLM ISO Abbreviation: J Stomatol Oral Maxillofac Surg Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Issy les Moulineaux Cedex : Elsevier Masson SAS, [2017]- |
| مواضيع طبية MeSH: | Mucormycosis*/diagnosis , Mucormycosis*/etiology , Mucormycosis*/therapy , COVID-19*/complications , COVID-19*/therapy, Male ; Female ; Humans ; Adult ; Middle Aged ; Antifungal Agents/therapeutic use ; Pandemics ; Debridement ; Hospitals |
| مستخلص: | This paper aims to discuss clinical aspects of mucormycosis. This case series was conducted in two services, comprising six mucormycosis cases during COVID-19 pandemic. About gender, there are 4 (66.7%) males and 2 (33.3%) females with mean age (48.7 ± 9.4) years. All cases presented complaints of pain and swelling in oral cavity and had an aggressive clinical presentation. Five patients had diabetes and one had a nasal non-Hodgkin lymphoma. Histologically, large, branched, hyphae associated with necrotic areas were observed, confirming microscopically such as mucormycosis through PAS and GMS stains. In four cases, treatment consisted in surgical debridement associated with antifungal therapy. All patients were submitted to debridement and received antifungal treatment (amphotericin B). Five patients were followed up without clinical recurrence, but unfortunately one patient died. Diagnosis of mucormycosis should be early because it is related to high mortality. The treatment consists of surgical debridement associated with antifungal therapy. Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2022 Elsevier Masson SAS. All rights reserved.) |
| References: | Int J Infect Dis. 2020 Aug;97:326-328. (PMID: 32526392) J Oral Maxillofac Pathol. 2021 May-Aug;25(2):219-222. (PMID: 34703112) J Oral Microbiol. 2021 Aug 26;13(1):1967699. (PMID: 34527182) Front Med (Lausanne). 2021 Jan 14;7:571214. (PMID: 33521007) Oral Maxillofac Surg. 2022 Sep;26(3):357-363. (PMID: 34622312) Oral Dis. 2022 Nov;28 Suppl 2:2591-2592. (PMID: 34289206) J Dent Res. 2021 Feb;100(2):141-154. (PMID: 32914677) Lancet Infect Dis. 2019 Dec;19(12):e405-e421. (PMID: 31699664) Lancet Respir Med. 2021 Aug;9(8):e77. (PMID: 34090607) J Maxillofac Oral Surg. 2021 Jun;20(2):165-166. (PMID: 33814812) |
| فهرسة مساهمة: | Keywords: Coronavirus; Infections; Mucormycosis; Oral diagnosis |
| المشرفين على المادة: | 0 (Antifungal Agents) |
| تواريخ الأحداث: | Date Created: 20220614 Date Completed: 20221101 Latest Revision: 20230424 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC9188452 |
| DOI: | 10.1016/j.jormas.2022.06.003 |
| PMID: | 35700951 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2468-7855 |
|---|---|
| DOI: | 10.1016/j.jormas.2022.06.003 |