دورية أكاديمية

Endovascular treatment of intracranial aneurysms using the Derivo Embolization Device: a multicenter experience.

التفاصيل البيبلوغرافية
العنوان: Endovascular treatment of intracranial aneurysms using the Derivo Embolization Device: a multicenter experience.
المؤلفون: Chagas Lourenço G; Department of Interventional Neuroradiology, Biocor Instituto, Nova Lima, Minas Gerais, Brazil galileucl@gmail.com., Dantas F; Department of Interventional Neuroradiology, Biocor Instituto, Nova Lima, Minas Gerais, Brazil., Silva E Carvalho T; Department of Interventional Neuroradiology, Biocor Instituto, Nova Lima, Minas Gerais, Brazil., Firmino RUR; Department of Interventional Neuroradiology, Biocor Instituto, Nova Lima, Minas Gerais, Brazil., Quesado Filgueiras Filho M; Department of Interventional Neuroradiology, Biocor Instituto, Nova Lima, Minas Gerais, Brazil., Tosello RT; Centro de Neuro-Angiografia, Hospital Beneficencia Portuguesa de Sao Paulo, Sao Paulo, Brazil., José Leão C; Department of Interventional Neuroradiology, Hospital Geral de Goiânia Dr Alberto Rassi, Goiania, Brazil., Leo Piske R; Department of Interventional Neuroradiology, Beneficência Portuguesa de São Paulo, Sao Paulo, Brazil., Zenóbio Darwich R; Department of Interventional Neuroradiology, Biocor Instituto, Nova Lima, Minas Gerais, Brazil.
المصدر: Journal of neurointerventional surgery [J Neurointerv Surg] 2023 Aug; Vol. 15 (8), pp. 776-780. Date of Electronic Publication: 2022 Jun 15.
نوع المنشور: Multicenter Study; Journal Article
اللغة: English
بيانات الدورية: Publisher: BMJ Publishing Group Country of Publication: England NLM ID: 101517079 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1759-8486 (Electronic) Linking ISSN: 17598478 NLM ISO Abbreviation: J Neurointerv Surg Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BMJ Publishing Group, c2009-
مواضيع طبية MeSH: Intracranial Aneurysm*/diagnostic imaging , Intracranial Aneurysm*/therapy , Intracranial Aneurysm*/complications , Embolization, Therapeutic*/methods , Endovascular Procedures*, Humans ; Retrospective Studies ; Cerebral Angiography/methods ; Treatment Outcome ; Stents ; Follow-Up Studies
مستخلص: Background: Flow diversion is the first-line treatment for several types of intracranial aneurysms. We report on a large series of patients treated with the Derivo Embolization Device who underwent a 1-year angiographic control follow-up.
Methods: We performed a multicenter retrospective analysis of prospectively collected data, designed to evaluate the clinical and angiographic results of treatment of intracranial aneurysms with the Derivo Flow Diverter. The primary endpoint was complete occlusion of the aneurysm within 12 months, which was evaluated using DSA. The secondary endpoint was the absence of any serious adverse events. Univariate and multivariate logistic regression analyses were performed to analyze the data.
Results: The study was conducted from December 2016 to September 2019 and enrolled 127 patients with 177 intracranial aneurysms, treated at three different centers. Efficacy at 6 months was 70.1% (122/174) for total occlusion and 87.3% (152/174) for favorable occlusion and, at 12 months, it was 83.3% (145/174) for total occlusion and 97.7% (170/174) for favorable occlusion. Regarding safety concerns, 97.6% (124/127) of patients did not experience severe adverse effects during the follow-up period of 12 months, and there was no procedure-related mortality.
Conclusions: The Derivo Embolization Device, achieving a total occlusion rate of 83.3% and a favorable occlusion rate of 97.7% in a 1-year angiographic control study of 174 aneurysms with minor morbidity and no intervention-related mortality, is a safe and effective treatment for intracranial aneurysms.
Competing Interests: Competing interests: None declared.
(© Author(s) (or their employer(s)) 2023. No commercial re-use. See rights and permissions. Published by BMJ.)
فهرسة مساهمة: Keywords: aneurysm; flow diverter; stent; stroke
تواريخ الأحداث: Date Created: 20220615 Date Completed: 20230717 Latest Revision: 20230718
رمز التحديث: 20231215
DOI: 10.1136/neurintsurg-2022-018648
PMID: 35705359
قاعدة البيانات: MEDLINE
الوصف
تدمد:1759-8486
DOI:10.1136/neurintsurg-2022-018648