دورية أكاديمية
Nonplatelet thromboxane generation is associated with impaired cardiovascular performance and mortality in heart failure.
العنوان: | Nonplatelet thromboxane generation is associated with impaired cardiovascular performance and mortality in heart failure. |
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المؤلفون: | Hariri E; Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts.; Department of Medicine, Cleveland Clinic Foundation, Cleveland, Ohio., Kakouros N; Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts., Bunsick DA; Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts., Russell SD; Division of Cardiology, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland., Mudd JO; Division of Cardiology, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland., Laws K; Division of Cardiology, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland., Lake MW; Division of Cardiology, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland., Rade JJ; Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts.; Division of Cardiology, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland. |
المصدر: | American journal of physiology. Heart and circulatory physiology [Am J Physiol Heart Circ Physiol] 2022 Jul 01; Vol. 323 (1), pp. H248-H255. Date of Electronic Publication: 2022 Jun 17. |
نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural |
اللغة: | English |
بيانات الدورية: | Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901228 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1539 (Electronic) Linking ISSN: 03636135 NLM ISO Abbreviation: Am J Physiol Heart Circ Physiol Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Bethesda, Md. : American Physiological Society, |
مواضيع طبية MeSH: | Heart Failure*/diagnosis , Ventricular Function, Left*, Humans ; Stroke Volume ; Thromboxane B2/urine ; Thromboxanes |
مستخلص: | Nonplatelet thromboxane generation, stimulated largely by oxidative stress, is a novel mortality risk factor in individuals with coronary artery disease. Though inversely associated with left ventricular ejection fraction (LVEF), a potential role in the pathobiology of heart failure (HF) remains poorly defined. Nonplatelet thromboxane generation and oxidative stress were assessed by measuring urine thromboxane-B |
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معلومات مُعتمدة: | TL1 TR001454 United States TR NCATS NIH HHS |
فهرسة مساهمة: | Keywords: heart failure; hemodynamics; outcome; thromboxane |
سلسلة جزيئية: | figshare 10.6084/m9.figshare.20052125.v1 |
المشرفين على المادة: | 0 (Thromboxanes) 54397-85-2 (Thromboxane B2) |
تواريخ الأحداث: | Date Created: 20220617 Date Completed: 20220711 Latest Revision: 20230703 |
رمز التحديث: | 20240628 |
مُعرف محوري في PubMed: | PMC9273282 |
DOI: | 10.1152/ajpheart.00212.2022 |
PMID: | 35714178 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1522-1539 |
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DOI: | 10.1152/ajpheart.00212.2022 |